Protein Alignment CG6414 and Ache

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_036020624.1
• Gene: Ache / 11423
• MGIID: 87876
• Length: 616
• Species: Mus musculus
• Alignment Length: 620
• Identity: 202/620 - (32%)
• Similarity: 278/620 - (44%)
• Gaps: 120/620 - (19%)

  Fly    22 SDGRNSQCLHVRLSHGGWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLA 86
            ::||....|.||: .||.|.|..|....| .:.||:|:|:||||:...||.||.||.||.|...|
Mouse    31 AEGREDPQLLVRV-RGGQLRGIRLKAPGG-PVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDA 93

  Fly    87 IKDAPICLQR--------------DPFRRDMILEGSEDCLYLNVYTPERPRTNGSLPVMVWFHGG 137
            .....:|.|.              :|.|     |.|||||||||:|| .||.....||::|.:||
Mouse    94 TTFQNVCYQYVDTLYPGFEGTEMWNPNR-----ELSEDCLYLNVWTP-YPRPASPTPVLIWIYGG 152

  Fly   138 GWQCGSGISSFYGPDFLLD-HDIVLVSANFRLGPLGFLSTE-TLDCPGNNGLKDQLEVLHWVRAN 200
            |:..|:.....|...||.. ...||||.|:|:|..|||:.. :.:.|||.||.||...|.||:.|
Mouse   153 GFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217

  Fly   201 IASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQPAHKGVAAGRATK 265
            ||:|||||.|||:||||||.|||..|:||..||.|.||.:.||||...||| ....|.|..|||.
Mouse   218 IAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWA-TVSAGEARRRATL 281

  Fly   266 LAQIVGC---GNAGEWPEKLECLRKKPAEDIVASLYDMFVWDFDPMIPFPPVVEPEHDGAFLTVA 327
            ||::|||   |..|...|.:.|||.:||:|:|...:.:...:......|.|||    ||.||:..
Mouse   282 LARLVGCPPGGAGGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVV----DGDFLSDT 342

  Fly   328 PRQAAKPHGLQ-LPLMVGATAEEG-----------------LLKTAALL-----NLPQ---LLAE 366
            |.........| |.::||...:||                 |:..|..|     .:||   |.||
Mouse   343 PEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAE 407

  Fly   367 FKSQFEQVLPVVLNYD---HHDDSVRQTITQRIESFYFKSGHDYDKANHQNLTDLISDGWFVAGI 428
                     .|||:|.   |.:|..                |..|.     ::.::.|...|..:
Mouse   408 ---------AVVLHYTDWLHPEDPT----------------HLRDA-----MSAVVGDHNVVCPV 442

  Fly   429 DEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGRELFVSAVP 493
            .: |..|::.:. |..|.|:|:|:.:.....:       :.|..|..|::::|  |..|..|...
Mouse   443 AQ-LAGRLAAQG-ARVYAYIFEHRASTLTWPL-------WMGVPHGYEIEFIF--GLPLDPSLNY 496

  Fly   494 TQKDLELRELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGTKMEDSASIFRLENE 558
            |.::....:.::..|.:||:||:||....| ..|.|.|.::...::..|..|.      ..:...
Mouse   497 TTEERIFAQRLMKYWTNFARTGDPNDPRDS-KSPQWPPYTTAAQQYVSLNLKP------LEVRRG 554

  Fly   559 LMQHRVDFWRDLQPHLPA-----------SHAHNE 582
            |......||....|.|.:           |.||.|
Mouse   555 LRAQTCAFWNRFLPKLLSATATEAPCTCPSPAHGE 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	192/586 (33%)
Ache	XP_036020624.1	COesterase	37..563	CDD:395084	192/586 (33%)