Protein Alignment CG6414 and Ces1d

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_444430.2
• Gene: Ces1d / 104158
• MGIID: 2148202
• Length: 565
• Species: Mus musculus
• Alignment Length: 620
• Identity: 173/620 - (27%)
• Similarity: 278/620 - (44%)
• Gaps: 98/620 - (15%)

  Fly     6 GLWSIRVILLCICIQWSDGRNSQCLHVRLSHGGWLIGRHLTTHN-GRHMRAFMGVPYAEPPLDDL 69
            ||:.:..:.|..|..|....:...::   :..|.::|:::.... .:.:..|:|||:|:|||..|
Mouse     2 GLYPLIWLSLAACTAWGYPSSPPVVN---TVKGKVLGKYVNLEGFTQPVAVFLGVPFAKPPLGSL 63

  Fly    70 RFRPPVPKAPWEGERLAIKDAPICLQ--------RDPF--RRDMI-LEGSEDCLYLNVYTPERPR 123
            ||.||.|..||...:......|:|.|        .:.|  |::.| |:.||||||||:|||....
Mouse    64 RFAPPQPAEPWSFVKNTTSYPPMCSQDAVGGQVLSELFTNRKENIPLQFSEDCLYLNIYTPADLT 128

  Fly   124 TNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLDHDIVLVSANFRLGPLGFLSTETLDCPGNNGLK 188
            .|..||||||.||||...| |.|::.|.......::|:|:..:|||..||.||......||.|..
Mouse   129 KNSRLPVMVWIHGGGLVVG-GASTYDGLALSAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192

  Fly   189 DQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQP 253
            ||:..|.||:.|||:|||:|.|||:|||||||.||:..:||..::.|.||.|::||.........
Mouse   193 DQVAALRWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNLFHRAISESGVSLTAALIT 257

  Fly   254 AHKGVAAGRATKLAQIVGCGNAGEWPEKLECLRKKPAEDIVASLYDMFVWDFDPM------IPFP 312
            ......||   .:|.:.||..... ...:.|||:|..::::.:...:.::..|.:      .||.
Mouse   258 TDVKPIAG---LVATLSGCKTTTS-AVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFL 318

  Fly   313 PVVEPEHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPV 377
            |.|   .||..|..||                    |.:|...:...:|.::...|.:|..::|.
Mouse   319 PTV---IDGVVLPKAP--------------------EEILAEKSFSTVPYIVGINKQEFGWIIPT 360

  Fly   378 VLNYDHHDDSVRQTITQRIESFYFKS-------------------GHDYDKANHQNL-TDLISDG 422
            ::.|...:..:.|   :...|..:||                   |...|....::| .||::|
Mouse   361 LMGYPLAEGKLDQ---KTANSLLWKSYPTLKISENMIPVVAEKYLGGTDDLTKKKDLFQDLMAD- 421

  Fly   423 WFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGREL 487
             .|.|:...:..|..::..|.||:|.|:::  .||....   |.:.....|.:|   :|.:....
Mouse   422 -VVFGVPSVIVSRSHRDAGASTYMYEFEYR--PSFVSAM---RPKAVIGDHGDE---IFSVFGSP 477

  Fly   488 FVSAVPTQKDLELRELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGTKMEDSASI 552
            |:....::::..|.::::..|.:||:.||||...    ||:| |.......:.::|...:.:
Mouse   478 FLKDGASEEETNLSKMVMKFWANFARNGNPNGGG----LPHW-PEYDQKEGYLKIGASTQAA--- 534

  Fly   553 FRLENELMQHRVDFWRDLQ----PHLPASHAHNEL 583
                ..|....|.||.:|:    ...|:...|.||
Mouse   535 ----QRLKDKEVSFWAELRAKESAQRPSHREHVEL 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	161/576 (28%)
Ces1d	NP_444430.2	COesterase	22..545	CDD:395084	161/578 (28%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565		1/2 (50%)