Protein Alignment CG6414 and Ces2

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001177298.1
• Gene: Ces2 / 100910144
• RGDID: 6504334
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 584
• Identity: 188/584 - (32%)
• Similarity: 272/584 - (46%)
• Gaps: 78/584 - (13%)

  Fly    12 VILLCICIQWSDGRNSQCLHVRLSHGGWLIGR--HL-TTHNGRHMRAFMGVPYAEPPLDDLRFRP 73
            ::||.|.:|..|...|.  .:|.:|.|.:.|:  |: .|..|.|  .|:|:|:|:||:..|||.|
  Rat    17 LLLLLIHVQGQDSPESS--PIRTTHTGQVQGKLDHVKDTKAGVH--TFLGIPFAKPPVGPLRFAP 77

  Fly    74 PVPKAPWEGERLAIKDAPICLQRDPFRRD-------MILEG---SEDCLYLNVYTPERPRTNGSL 128
            |.|..||.|.|.|.....:|||......:       |||..   ||||||||||.|...|...:|
  Rat    78 PEPPEPWSGVRDATSQPAMCLQNLDILDEVGLLDMKMILSSISMSEDCLYLNVYAPAHAREGSNL 142

  Fly   129 PVMVWFHGGGWQCGSGISSFYGPDFL-LDHDIVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLE 192
            |||||.|||....  |::|.|....| ::.|:|:|:..:|||.|||.||......||.|..||:.
  Rat   143 PVMVWIHGGALVV--GMASMYDGSLLTVNEDLVVVTIQYRLGVLGFFSTGDEHARGNWGYLDQVA 205

  Fly   193 VLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQPAHKG 257
            .|.||:.|||.|||:||.||:|||||||.||:.|::|..|:||.|..|.:||....|   .....
  Rat   206 ALRWVQQNIAHFGGNPNRVTIFGESAGGTSVSSHVISPMSQGLFHGAIMESGVALLP---DLISE 267

  Fly   258 VAAGRATKLAQIVGCGNAGEWPEKLECLRKKPAEDI--VASLYDMFVWDFDPMIPFPPVVEPEHD 320
            .:...:|.:|::.|| .|.:....:.|||.|...:|  :..::.|          .|.||    |
  Rat   268 TSETVSTTVAKLSGC-EAMDSEALVRCLRAKSGAEILVINKVFKM----------IPAVV----D 317

  Fly   321 GAFLTVAPRQAAKPHGLQ-LPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVVLNYDHH 384
            |.||...|::........ :|.::|...:|.......::...|::.|..   .:.|..||.
  Rat   318 GEFLPRHPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKELS---RENLQAVLK---- 375

  Fly   385 DDSVRQTITQRIESFYFKS--GHDYDKANHQ-NLTDLISDGWFVAGIDEYLRLRMSQEDVAPTYV 446
            |.:.:..:.........:.  |:..|....| ..|:::.|..||.   ..|::...|...||.|.
  Rat   376 DTAAQMMLPPECGDLLMEEYMGNTDDSQTLQIQYTEMMGDFLFVI---PALQVAHFQRSHAPVYF 437

  Fly   447 YLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGRELFVSAVP---TQKDLELRELMLHLW 508
            |.|.|  |.|:   ||..|.....|.||:|:.::|    ..|.|.:.   |:::..|...|:..|
  Rat   438 YEFQH--APSY---FKNVRPPHVKADHADEVPFVF----GSFFSGMKLDFTEEERLLSRRMMKYW 493

  Fly   509 VSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGTKMEDSASIFRLENELMQHRVDFWRDLQP 572
            .:||:.||||    |..||.| ||..:..::.:|.|..       .::..|...|:.||....|
  Rat   494 ANFARQGNPN----SEGLPYW-PALDHDEQYLQLDTHP-------AVDRALKARRLQFWTKTLP 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	179/561 (32%)
Ces2	NP_001177298.1	COesterase	32..540	CDD:395084	180/562 (32%)