DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6414 and bche

DIOPT Version :9

Sequence 1:	NP_001303565.1	Gene:	CG6414 / 31352	FlyBaseID:	FBgn0029690	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_002931610.1	Gene:	bche / 100495889	XenbaseID:	XB-GENE-980117	Length:	602	Species:	Xenopus tropicalis

Alignment Length:	603	Identity:	188/603 - (31%)
Similarity:	277/603 - (45%)	Gaps:	95/603 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LWSIRVILLCICIQWSDGRNSQCLHVRLSHGGWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRF 71
            :::|...::|||....:|...    :..:..|.:.|..::..:| .:.||:|:||||||:.||||
Frog    11 IFTICFTVVCICCVNCNGETD----IVDTKYGKVTGVQISVFSG-IITAFLGIPYAEPPIGDLRF 70

  Fly    72 RPPVPKAPWEGERLAIKDAPICLQRDPFRRDMILEG-------------SEDCLYLNVYTPERPR 123
            :.|||..||.....|.:....|.|    ..|.|..|             ||||||||::.|....
Frog    71 KKPVPHKPWSEIWNASQYGNSCYQ----TVDQIFPGFSGAEMWNPNTQLSEDCLYLNIWIPTPKP 131

  Fly   124 TNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLDHD-IVLVSANFRLGPLGFLS-TETLDCPGNNG 186
            .|.|  ||||.:||.::.|:.....|...||...: :::||.|:|||.||||: ....:.|||.|
Frog   132 RNAS--VMVWIYGGSFETGTSSLDLYDGKFLARTERVIVVSMNYRLGALGFLAFPGNNEAPGNVG 194

  Fly   187 LKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWA 251
            |.||...|.||..|||:|||:|.|:|:||||||||||:|||||.||.|...|.|.||.|...|||
Frog   195 LFDQRLALQWVYENIAAFGGNPKSITIFGESAGGASVSYHMLSPKSHGFFTRAIMQSATANAPWA 259

  Fly   252 QPAHKGVAAGRATKLAQIVGCGNAGEWPEKLECLRKKPAEDIVASLYDMFVWDFDPMIPFPPVVE 316
             ...|..|:.||..||.::.|....| .|.:.|||.|..|:|......:........:.|||.|
Frog   260 -VITKAEASNRALTLANLLNCFYRNE-TEIIACLRNKSPEEIFEKAVSVLPHRSVIEVNFPPTV- 321

  Fly   317 PEHDGAFLTVAPR------QAAKPHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVL 375
               ||.||...|.      |..|    :..::.|...:||  ....:..||....:.:|
Frog   322 ---DGDFLIEMPEILMQLGQLKK----KTQILTGVNKDEG--SYFLVYGLPGFSKDHES------ 371

  Fly   376 PVVLNYDHHDDSVRQTITQRIE------SFYFKSGHDYDKANHQN--LTDLISDGWFVAGIDEYL 432
              .:|......||:....:..|      .|::.:..|....:|..  :.|::.|..|:..:.|:.
Frog   372 --FINRTQFHKSVKLAFPKATELAIDSVLFHYTNWEDEQNPSHNRDAMDDIVGDYNFICPLLEFT 434

  Fly   433 RLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLF--PIGRELFVSAVPTQ 495
            :......:.|  |:|.|.|: ::..|  :.|    :.|..|..|::::|  |:.|.|..    |:
Frog   435 KWNSELGNNA--YLYYFHHR-SSKLT--WPG----WMGVMHGYEIEFVFGIPMYRRLNY----TK 486

  Fly   496 KDLELRELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPV------EFARLGTKMEDSASIFR 554
            .:..|...::..|.:||||||||...        |..:.:||      .:..|||  |||    :
Frog   487 AEETLSRTLMRYWANFAKTGNPNGAQ--------SSENRWPVFTLDEQHYLMLGT--EDS----K 537

  Fly   555 LENELMQHRVDFWRDLQP 572
            ...::...:..||.:..|
Frog   538 TNRKMRAKQCRFWNNFYP 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	180/567 (32%)
CG6414	NP_001303565.1	Aes	<116..>254	CDD:223730	68/139 (49%)
bche	XP_002931610.1	COesterase	32..550	CDD:365897	180/571 (32%)
bche	XP_002931610.1	AChE_tetra	565..599	CDD:370053
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D379826at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020