Protein Alignment CG6414 and ache

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_002940088.1
• Gene: ache / 100490673
• XenbaseID: XB-GENE-923160
• Length: 600
• Species: Xenopus tropicalis
• Alignment Length: 640
• Identity: 181/640 - (28%)
• Similarity: 266/640 - (41%)
• Gaps: 162/640 - (25%)

  Fly    10 IRVILLCICIQWSDGRNSQCLHVRL------SHGGWLIGRHLTTHNGR-----------HMRAFM 57
            :.:..||:|          .|.:.|      |.||.|:    :|.:|:           |:.||:
 Frog     4 VPIAQLCLC----------TLSLLLVPALTQSDGGLLV----STRSGKVRGLRQPVLSTHVSAFL 54

  Fly    58 GVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDPFRRDMILEG-------------SE 109
            |:|:||||:|.:|||...||.||.....|......|.|    ..|.:..|             ||
 Frog    55 GIPFAEPPVDKMRFRRSEPKKPWTDVWDATAYPNACYQ----YFDTLYPGFPGMEMWNPNRPMSE 115

  Fly   110 DCLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLD-HDIVLVSANFRLGPLGF 173
            ||||||::.| .||.:.: .||||.:|||:..||.....|...:|.. .::::||.|:|:|..||
 Frog   116 DCLYLNIWVP-HPRPSNA-TVMVWIYGGGFYSGSSSLDVYDGRYLCHAENVIVVSMNYRVGAFGF 178

  Fly   174 LSTE--TLDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLL 236
            |:..  ::|.|||.||.||...|.||:.|||.|||||.:||:||||||..||..|:||..|..|.
 Frog   179 LTLTPGSVDAPGNVGLFDQRLALQWVQDNIAFFGGDPRTVTIFGESAGAVSVGMHVLSPGSHHLF 243

  Fly   237 HRGIAQSGTYFNPWA----QPAHKGVAAGRATKLAQIVGCGNAGEWPEKLECLRKKPAEDIVASL 297
            .:...|||:...|||    |.|.:     |...|.:.:.| ..|...|.|.|||.|..::::...
 Frog   244 SKAALQSGSPNTPWATITPQEARR-----RTELLGKFLDC-RMGNDTELLNCLRVKQPQELIDHE 302

  Fly   298 YDMFVWDFDPMIPFPPVVE----PEHDGAFLTVAPR-----QAAKPHGLQLPLMVGATAEEG--- 350
            :.        ::|.|.|..    |..|..|....|.     ...||    .||::|....||
 Frog   303 FS--------VLPAPSVFRFAFVPVPDADFFPEPPEILMNMGRFKP----CPLIMGVNQNEGSYF 355

  Fly   351 LLKTA--------ALLNLPQLLAEFKSQFEQ-----VLPVVLNY-----DHHDDSVRQTITQRIE 397
            ||..|        :|:...:.|...|....|     :..||:.|     :|.....|:.:.|.:
 Frog   356 LLYGAPGFSKNNESLITREEFLGGVKMSVPQANDIALEAVVMQYTDWADEHAGVKNREAMDQLV- 419

  Fly   398 SFYFKSGHDYDKANHQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPT----YVYLFDHKGAASFT 458
                        .:|..:..|.    :.||            .||.|    |.|.|||:.:
 Frog   420 ------------GDHNVICPLT----YFAG------------KVAETGNRVYTYFFDHRAS---- 452

  Fly   459 EIFKGGRN----EFYGACHAEELQYLFPIGRELFVSAVPTQKDLELRELMLHLWVSFAKTGNPNP 519
                   |    ::.|..|..|::::|.:..:..::..|.::.|..|  |:..|.:||:||:||.
 Frog   453 -------NLAWPQWMGVPHGYEIEFVFGLPLDANLNYTPQEEALSRR--MMRYWANFARTGDPNE 508

  Fly   520 TNVSFHLPNWSPASSYPVEFARLGTKMEDSASIFRLENELMQHRVDFWRDLQPHL 574
            .| ..|.|.|...::....:..|..|........|::..:      ||....|.|
 Frog   509 GN-DAHQPRWPLYTASEQRYMALNNKPYQELQGIRVQTCM------FWNRFLPKL 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	171/599 (29%)
		Aes	<116..>254	CDD:223730	63/144 (44%)
ache	XP_002940088.1	COesterase	31..549	CDD:395084	168/594 (28%)
		AChE_tetra	564..597	CDD:400834

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910