Protein Alignment CG6414 and nlgn1

DIOPT Version :9

• Sequence 1: NP_001303565.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_017213657.1
• Gene: nlgn1 / 100002610
• ZFINID: ZDB-GENE-090918-1
• Length: 867
• Species: Danio rerio
• Alignment Length: 642
• Identity: 192/642 - (29%)
• Similarity: 267/642 - (41%)
• Gaps: 176/642 - (27%)

  Fly    56 FMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDPFRRDMILEG------------- 107
            |:|||||.||..:.||:||.|...|...|.|.:.||:|.|       .:|||
Zfish    81 FLGVPYAAPPTGERRFQPPEPPISWSEIRNATQFAPVCPQ-------TLLEGRLPDVMLPVWFTN 138

  Fly   108 ------------SEDCLYLNVYTP----------------------------------------- 119
                        |||||:||:|.|
Zfish   139 SIEVVSSYVQDQSEDCLFLNIYVPTEDVKRISKECARKPGKKICRKGGPLSKKQNDDLADNDGAE 203

  Fly   120 -ERPRTNGS-LPVMVWFHGGGWQCGSG------ISSFYGPDFLLDHDIVLVSANFRLGPLGFLST 176
             |..|.:|| .||||:.|||.:..|:|      |.:.||       ::::::.|:|||.||||||
Zfish   204 DEDIRESGSPKPVMVFVHGGSYMEGTGNMFDGSILASYG-------NVIVITVNYRLGVLGFLST 261

  Fly   177 ETLDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKS--------- 232
            ......||.||.|.::.|.|...|||.|||||..:||||..||.:.|....||..|
Zfish   262 GDQAAKGNYGLLDLIQALRWTSENIAFFGGDPLRITVFGSGAGASCVNLLTLSHYSEGNRWSNST 326

  Fly   233 RGLLHRGIAQSGTYFNPWA---QPAHKGVAAGRATKLAQIVGCGNAGEWPEKLECLRKKPAEDIV 294
            :||..|.||||||..:.||   |||.      .|..||:.||| |..:..|.:|||:||..:::|
Zfish   327 KGLFQRAIAQSGTALSSWAVSFQPAK------YARMLAKKVGC-NLKDTVEMVECLQKKHYKELV 384

  Fly   295 ASLYDMFVWDFDPM---IPFPPVVEPEHDGAFLTVAPRQAAKPHG--LQLPLMVGATAEEGLLKT 354
            ..       |..|.   |.|.||:    ||..:...| |.....|  |...:|:|....|| ||.
Zfish   385 EQ-------DIQPARYHIAFGPVI----DGDVIPDDP-QILMEQGEFLNYDIMLGVNQGEG-LKF 436

  Fly   355 AALL--NLPQLLA-EFKSQFEQVLPVVLNYDHHDDSVRQTITQRIESFYFKSGHD--YDKANHQN 414
            ..|:  |...:.| :|.......:..:..|....|.:|:||     .|.:....|  ..:...:.
Zfish   437 VELIVDNENGVQANDFDYAVSSFVDDLYGYPEGKDILRETI-----KFMYTDWADRHNPETRRKT 496

  Fly   415 LTDLISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQY 479
            |..|.:|..:||.......|..|..  :|||.|.|.|........       .:..|.|.:|:.|
Zfish   497 LLALFTDHQWVAPAVATADLHSSFG--SPTYFYAFYHHCQTEQVP-------PWADAAHGDEIPY 552

  Fly   480 LF---PIG-RELFVSAVP---TQKDLELRELMLHLWVSFAKTGNPN---PTNVSF-HL-PN---- 528
            :|   .|| .|||    |   ::.|:.|..:::..|.:|||||:||   |.:..| |. ||
Zfish   553 VFGLPMIGPTELF----PCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEE 613

  Fly   529 --WSPASSYPVEFARLGTKMEDSASIFRLENELMQHRVDFWRDLQPHLPASHAHNEL 583
              |:..:.....:..:|.|.       |::.....::|:.|.:|.|||   |:.||:
Zfish   614 VAWTRYNQKDQLYLHIGLKP-------RVKEHYRANKVNLWLELVPHL---HSLNEV 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	184/624 (29%)
		Aes	<116..>254	CDD:223730	65/198 (33%)
nlgn1	XP_017213657.1	COesterase	53..647	CDD:306613	184/624 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810