Protein Alignment CG6414 and nlgn2b

DIOPT Version :10

• Sequence 1: NP_570089.1
• Gene: CG6414 / 31352
• FlyBaseID: FBgn0029690
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 666
• Identity: 190/666 - (28%)
• Similarity: 279/666 - (41%)
• Gaps: 173/666 - (25%)

  Fly    18 CIQWSDG-----RNSQCLHVRLSHGGWLIGRH--LTTHNGR--------------HMRAFMGVPY 61
            |:.|..|     ..|.|....|:     ..:|  :||..|:              .:..::||||
Zfish    25 CLVWLLGLALRLALSSCQRADLT-----TAKHPMVTTGYGKLRGVRKELNNEILGPVEQYLGVPY 84

  Fly    62 AEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDP-----------FRRDM------ILEGSE 109
            |.||:.:.||:||.....|:..|.|.:.||:|.|...           |..::      :...||
Zfish    85 ATPPVGERRFQPPEAPGSWQEIRNATQFAPVCPQNIHGVLPEIMLPVWFTDNLDAAAAYVQNQSE 149

  Fly   110 DCLYLNVYTP---------------ERPRTNG-----SLPVMVWFHGGGWQCGSG------ISSF 148
            ||||||||.|               .|||...     ..|||::.|||.:..|:|      :.:.
Zfish   150 DCLYLNVYVPTEDGPLTKKHDESSMNRPRDEDIRDRRKKPVMLFIHGGSFMEGTGNMFDASVLAA 214

  Fly   149 YGPDFLLDHDIVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTV 213
            ||       ::::|:.|:|||.|||||:......||.||.||::.|.|:..||..|||||..:|:
Zfish   215 YG-------NVIVVTMNYRLGVLGFLSSGDQSAKGNYGLLDQIQALRWLNENIGHFGGDPERITI 272

  Fly   214 FGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWA---QPAHKGVAAGRATK-LAQIVGCGN 274
            ||..||.:.|...:||..|.||..|.|||||:..:.|:   :|.       ..|| ||:.||| :
Zfish   273 FGSGAGASCVNLLILSHHSEGLFQRAIAQSGSAISSWSVNYRPL-------MYTKILAKKVGC-S 329

  Fly   275 AGEWPEKLECLRKKPAEDIVASLYDMFVWDFDPM---IPFPPVV-------EPE---HDGAFLT- 325
            ..:..:.::|||:|...::|..       |..|.   |.|.|||       :||   ..|.||.
Zfish   330 YSDTADLVDCLRRKSYRELVDQ-------DVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNY 387

  Fly   326 ---VAPRQAAKPHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVVLNYDHHDDS 387
               :...|     |..|..:.....|||:           ..|.|.......:..:..|....|.
Zfish   388 DILLGVNQ-----GEGLKFVDDNEGEEGI-----------SAASFDYTISNFVDNLYGYPEGKDI 436

  Fly   388 VRQTITQRIESFYFKSGHDYDKAN--HQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFD 450
            :|:||     .|.:....|.|..:  .:.|..|.:|..:||  ......::..|..:|.|.|.|.
Zfish   437 LRETI-----KFMYTDWADRDNGDMRRKTLLALFTDHQWVA--PAVATAKLHAEFQSPVYFYTFH 494

  Fly   451 HKGAASFTEIFKGGRNEFYGACHAEELQYLFPI----GRELFVSAVP---TQKDLELRELMLHLW 508
            |.   ..||    .|.|:..|.|.:|:.|:|.:    ..|||    |   ::.|:.|..:::..|
Zfish   495 HH---CQTE----ARPEWADAAHGDEIPYVFGVPMVGATELF----PCNFSKNDIMLSAVVMTYW 548

  Fly   509 VSFAKTGNPN---PTNVSF-HL-PN------WSPASSYPVEFARLGTKMEDSASIFRLENELMQH 562
            .:|||||:||   |.:..| |. ||      |:..||...::..:|.|.       |:.:....:
Zfish   549 TNFAKTGDPNIPVPQDTKFIHTKPNRFEEVIWTKFSSKDKQYLHIGLKP-------RIRDNYRAN 606

  Fly   563 RVDFWRDLQPHLPASH 578
            :|.||.:|.|||...|
Zfish   607 KVAFWLELVPHLHTIH 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6414	NP_570089.1	COesterase	28..567	CDD:395084	179/638 (28%)
nlgn2b	NP_001159808.1	COesterase	52..611	CDD:395084	176/621 (28%)