Protein Alignment CG6428 and ASPG

DIOPT Version :10

• Sequence 1: NP_570088.1
• Gene: CG6428 / 31351
• FlyBaseID: FBgn0029689
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: XP_016876754.1
• Gene: ASPG / 374569
• HGNCID: 20123
• Length: 670
• Species: Homo sapiens
• Alignment Length: 496
• Identity: 203/496 - (40%)
• Similarity: 290/496 - (58%)
• Gaps: 26/496 - (5%)

  Fly   116 DRRVIYQISEYTPLLDSSNMTMNDWARIASDIQQSYEFFDGFVVLHGTDTLSYTASALSFMLENL 180
            ::|::|.:.|..||.|||:||:.:|..:|..|::.||.:.||||:|||||:::.||.||||||||
Human    97 NQRILYTVLECQPLFDSSDMTIAEWVCLAQTIKRHYEQYHGFVVIHGTDTMAFAASMLSFMLENL 161

  Fly   181 GKTVIITGSQIPIFETRTDGKDNFTSALIIAGNYIIPEVCIFFGHKLMRGNRTVKVSSNALDAFD 245
            .||||:||:|:||....:||::|...||::||.|:|||||:||.::|.||||..||.:....||.
Human   162 QKTVILTGAQVPIHALWSDGRENLLGALLMAGQYVIPEVCLFFQNQLFRGNRATKVDARRFAAFC 226

  Fly   246 SPNVPPLARIGIDVNVDYRLIFRPCTIERFCVHLNLDENVGLLRIFPSISHSTFRAFLAPPIRGV 310
            |||:.|||.:|.|:.::..|:.:........||.:::::|||||::|.|..:..||||.||::||
Human   227 SPNLLPLATVGADITINRELVRKVDGKAGLVVHSSMEQDVGLLRLYPGIPAALVRAFLQPPLKGV 291

  Fly   311 VLQSFGSGNIPSNRKDLIDELRAAGERGVIIINCTQCPNGTVAEIYDTGKVLCDVGVIPGFDMTP 375
            |:::|||||.|: :.||:.|||.|.|||::|:|||.|..|.|...|..|..:...|||.|||||.
Human   292 VMETFGSGNGPT-KPDLLQELRVATERGLVIVNCTHCLQGAVTTDYAAGMAMAGAGVISGFDMTS 355

  Fly   376 EAALAKLAYVIGKEEWSLDMKKQMMQSSLRGELT----SLKAPKMEDYDLVDAVARSLHLSSPQE 436
            |||||||:||:|:...|||::|:::...||||:|    ..:.|.::...|...|:..|.||..||
Human   356 EAALAKLSYVLGQPGLSLDVRKELLTKDLRGEMTPPSVEERRPSLQGNTLGGGVSWLLSLSGSQE 420

  Fly   437 LDQLGETLFPAMINAAVAEGDPKKINNLKAYGADLSGTNHDQRTALHLACQLGNVEIVKYLLQNG 501
            .|.|...|.|::..||...||.:.:..|...|:||...:.:.:|.||.|.:.|:.|.|..|||.|
Human   421 ADALRNALVPSLACAAAHAGDVEALQALVELGSDLGLVDFNGQTPLHAAARGGHTEAVTMLLQRG 485

  Fly   502 VSVHVRDRYDRTPLLEAV------------------ATDSHEIIQLLINC--GAHLTGSSRAVGE 546
            |.|:.||....:|||.||                  |....|...|.:.|  |..|:|.......
Human   486 VDVNTRDTDGFSPLLLAVRGRTRLTARPQPVSQPRSAARLPEAACLALLCLSGTPLSGCPAPTPT 550

  Fly   547 QLCAAAARGSMIRLKSYQYAGADLAQSDPSGRTALHVAALH 587
            |..:|......:||......|.|.......||:| |.:..|
Human   551 QGQSAGLIQCPLRLAEEVTTGCDQRLGVQWGRSA-HASGCH 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6428	NP_570088.1	L-asparaginase_like	51..409	CDD:469665	144/292 (49%)
		ANKYR	377..630	CDD:440430	76/235 (32%)
		ANK repeat	477..508	CDD:293786	13/30 (43%)
		ANK repeat	510..574	CDD:293786	18/83 (22%)
		ANK repeat	576..607	CDD:293786	5/12 (42%)
ASPG	XP_016876754.1	L-asparaginase_like	102..389	CDD:469665	143/287 (50%)
		ANKYR	<435..>504	CDD:440430	27/68 (40%)
		ANK repeat	461..492	CDD:293786	13/30 (43%)