DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vap33 and PVA12

DIOPT Version :9

Sequence 1:	NP_570087.1	Gene:	Vap33 / 31349	FlyBaseID:	FBgn0029687	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_182039.1	Gene:	PVA12 / 819122	AraportID:	AT2G45140	Length:	239	Species:	Arabidopsis thaliana

Alignment Length:	277	Identity:	69/277 - (24%)
Similarity:	121/277 - (43%)	Gaps:	56/277 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKSLFDLPLTIEPEHELRFVGPFTRPVVTIMTLRNNSALPLVFKIKTTAPKRYCVRPNIGKIIP 65
            ||..|    |||:|. :|:|.....:.:...:.|.|.:...:.||:|||.||:||||||.|.:.|
plant     1 MSNEL----LTIDPV-DLQFPFELKKQISCSLYLGNKTDNYVAFKVKTTNPKKYCVRPNTGVVHP 60

  Fly    66 FRSTQVEICLQPFVYDQQE-----KNKHKFMVQSVLAPMDADLSDL-NKLWKDLEPEQLMDAKLK 124
            ..|::|.:.:|.    |:|     :.|.||::|.|:|...|...|: ::::......::.:.||:
plant    61 RSSSEVLVTMQA----QKEAPADLQCKDKFLLQCVVASPGATPKDVTHEMFSKEAGHRVEETKLR 121

  Fly   125 CVF------EMPTAEANAENTSGGGAVGGGTGAAGGGSAGANTSSASAEALESKPKLSSEDKFKP 183
            .|:      ..|..|.:.|.:|...:|          |...|.|..:|....|..::.::|....
plant   122 VVYVAPPRPPSPVREGSEEGSSPRASV----------SDNGNASDFTAAPRFSADRVDAQDNSSE 176

  Fly   184 SNLLETSESLDLLSGEIKALRECNIELRRENLHLKDQITRFRSSPAVKQVNEPYAPVLAEKQIPV 248
            :..|.|.     |:.|..:..:.|..|::|...|:.:..|.:|.                 .||.
plant   177 ARALVTK-----LTEEKNSAVQLNNRLQQELDQLRRESKRSKSG-----------------GIPF 219

  Fly   249 FYIAVAIAAAIVSLLLG 265
            .|:   :...::.|:||
plant   220 MYV---LLVGLIGLILG 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vap33	NP_570087.1	Motile_Sperm	9..115	CDD:279029	36/111 (32%)
PVA12	NP_182039.1	Motile_Sperm	5..112	CDD:395510	37/115 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	58	1.000	Domainoid score	I3931
eggNOG	1	0.900	-	-		E1_COG5066
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1332028at2759
OrthoFinder	1	1.000	-	-		FOG0000705
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101143
Panther	1	1.100	-	-	LDO	PTHR10809
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X526
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.780