DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vap33 and MOSPD1

DIOPT Version :9

Sequence 1:	NP_570087.1	Gene:	Vap33 / 31349	FlyBaseID:	FBgn0029687	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_062456.1	Gene:	MOSPD1 / 56180	HGNCID:	25235	Length:	213	Species:	Homo sapiens

Alignment Length:	148	Identity:	35/148 - (23%)
Similarity:	59/148 - (39%)	Gaps:	17/148 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DLPLTIEPEHELRFVGPFTRPVVTIMTLRNNSALPLVFKIKTTAPKRYCVRPNIGKIIP------ 65
            :||:.:.|. ||.|..........::||.|.....|.||:..|.|.:|.|....|.:.|
Human    14 NLPVFVFPT-ELIFYADDQSTHKQVLTLYNPYEFALKFKVLCTTPNKYVVVDAAGAVKPQCCVDI 77

  Fly    66 -FRSTQVEIC----LQPFVYDQQEKNKHKFM-VQSVLAPMDADLSDLNKLWKDLEPEQLMDAKLK 124
             .|...|..|    :..|.....|:::.|.: .:.|:|.:   |....:..|:.|.::|.:...:
Human    78 VIRHRDVRSCHYGVIDKFRLQVSEQSQRKALGRKEVVATL---LPSAKEQQKEEEEKRLKEHLTE 139

  Fly   125 CV-FEMPTAEANAENTSG 141
            .: ||......|...:||
Human   140 SLFFEQSFQPENRAVSSG 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vap33	NP_570087.1	Motile_Sperm	9..115	CDD:279029	27/117 (23%)
MOSPD1	NP_062456.1	Motile_Sperm	16..115	CDD:334183	24/99 (24%)
MOSPD1	NP_062456.1	Nuclear export signal. /evidence=ECO:0000250\|UniProtKB:Q8VEL0	205..208
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5066
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900