DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vap33 and ZC196.2

DIOPT Version :9

Sequence 1:	NP_570087.1	Gene:	Vap33 / 31349	FlyBaseID:	FBgn0029687	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_505251.2	Gene:	ZC196.2 / 191101	WormBaseID:	WBGene00022546	Length:	345	Species:	Caenorhabditis elegans

Alignment Length:	263	Identity:	51/263 - (19%)
Similarity:	107/263 - (40%)	Gaps:	51/263 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 MTLRNNSALPLVFKIKTTAPKRYCVRPNIGKIIPFRSTQVEICLQPFVYDQQEKNKHKFMVQSVL 96
            :||:|.|..|:.||:||:.|..|..|||...:.|..:.|:.:..:...........:|..::|..
Worm    30 VTLKNISEKPVCFKVKTSVPNMYVSRPNPDLLKPGEARQLSVKFRSSDKVSLNAKSYKLKIESCE 94

  Fly    97 APMDADLSDLNKLWKDLEPEQLMDAKLKCVF---------------EMPTAEANAENTSGGGAVG 146
            ...: |:.||...|..:..|:::..|...:.               |.....:..:|.|..|...
Worm    95 FESE-DIDDLKSFWSSIPNEKILVHKSPIILGTGSSPDFRNDQIASESSRQSSPIQNVSDDGKSS 158

  Fly   147 GGTGAAGGGSAGANTSS-------------ASAEALESKPKLSSEDKFKPSNLLETS-ESLDLLS 197
            ..:.|........|:.|             .:.:|.::......:|:|:..|.||.. :.:|.:.
Worm   159 HHSTAKQLQENNENSKSLKYTKQLVEVPLGENQQADQTGTTCDKKDEFQKKNQLEVEIKFVDKIH 223

  Fly   198 GEIKALRECNIELRRENLHLK---------DQITRF------RSSPA----VKQVNEPYAPVLAE 243
             |||:..|.:.||:.:.:.::         .::|:|      .:||.    |.::::.:: ::|:
Worm   224 -EIKSQLEDSFELKLKEMEMRLEEKFEKRISRLTQFMETISLSNSPGNSRRVFELDDNFS-IVAK 286

  Fly   244 KQI 246
            |::
Worm   287 KEL 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vap33	NP_570087.1	Motile_Sperm	9..115	CDD:279029	22/82 (27%)
ZC196.2	NP_505251.2	Motile_Sperm	7..112	CDD:279029	22/82 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5066
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000705
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101143
Panther	1	1.100	-	-	O	PTHR10809
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.770