DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42541 and Rrad

DIOPT Version :9

Sequence 1:	NP_996345.3	Gene:	CG42541 / 31344	FlyBaseID:	FBgn0260658	Length:	1418	Species:	Drosophila melanogaster
Sequence 2:	NP_062636.2	Gene:	Rrad / 56437	MGIID:	1930943	Length:	307	Species:	Mus musculus

Alignment Length:	216	Identity:	69/216 - (31%)
Similarity:	97/216 - (44%)	Gaps:	35/216 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   973 SVTSTGTSNSG--VD----RHNSNASGASGEVIDGDPNVPAYKIAMLGASGVGKTTLTYQFTTSD 1031
            :.|:.||...|  :|    ..:|.:||.||.. :|     .||:.:|||.||||:.|...|.
Mouse    56 ATTAAGTRTQGQRLDWPEGSSDSLSSGGSGSE-EG-----VYKVLLLGAPGVGKSALARIFG--- 111

  Fly  1032 YICAYDLSLDDDYGQKTV------SVLVDNIETDLEIID----HPACEMSTEAFCATYNIDLFVV 1086
                   .::|....:..      |:.||..|..|.:.|    ...|.:  ...|.... |.:|:
Mouse   112 -------GIEDGPEAEAAGHTYDRSITVDGEEASLLVYDIWEQDGGCWL--PGHCMAMG-DAYVI 166

  Fly  1087 VYSVIDRNTFAAAERVLQYLKENEMLLSRGAILVANKTDLQRHRVVTRQMGRKVAKEIACKFIET 1151
            |||:.|:.:|..|..:...|:..........|||.||:||.|.|.|:...||..|....||||||
Mouse   167 VYSITDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIET 231

  Fly  1152 SSGLDHNVDELLVGIVAQVKL 1172
            |:.|.|||..|..|:|.|::|
Mouse   232 SAALHHNVQALFEGVVRQIRL 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42541	NP_996345.3	RGK	1008..>1175	CDD:206715	58/175 (33%)
CG42541	NP_996345.3	small_GTPase	1008..1171	CDD:197466	57/172 (33%)
Rrad	NP_062636.2	RGK	91..307	CDD:206715	58/175 (33%)
Rrad	NP_062636.2	Calmodulin-binding. /evidence=ECO:0000250	277..296
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D301527at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8675
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45775
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920