Protein Alignment CG42541 and REM2

DIOPT Version :9

• Sequence 1: NP_996345.3
• Gene: CG42541 / 31344
• FlyBaseID: FBgn0260658
• Length: 1418
• Species: Drosophila melanogaster
• Sequence 2: XP_016876547.1
• Gene: REM2 / 161253
• HGNCID: 20248
• Length: 373
• Species: Homo sapiens
• Alignment Length: 368
• Identity: 98/368 - (26%)
• Similarity: 150/368 - (40%)
• Gaps: 94/368 - (25%)

  Fly   827 GNGDSTDSPSPVSMIPSNQQKQQQQLLQLQLQQEQQHLPTHLPMKRERGVGESSGASTSGTAIAE 891
            |||.......|:.:        :|..|.|      .|:..|:|:.          ||.|..:...
Human    25 GNGHQVGVAGPLIL--------EQPGLSL------LHMVEHIPLI----------ASFSLPSHFI 65

  Fly   892 LASSVVLATQSGKPMTERQRLRTSSMPAESRRPRLAEMRRSAIHAGDPDMTYYRLRSFSITSHGI 956
            |.:...|..:|.|.:.|..|   |.:|:....||    ||     |...:.|         .|.:
Human    66 LEADATLLKKSEKLLAELDR---SGLPSAPGAPR----RR-----GSMPVPY---------KHQL 109

  Fly   957 CNLGDSLRSRRSRSINSVT-STGTSNSGVDRHNSNASGASGEVI----DGDPNVPAYKIAMLGAS 1016
                     ||:::::.:. ....|:||     |:.|..|||..    ||     .:|:.::|.|
Human   110 ---------RRAQAVDELDWPPQASSSG-----SSDSLGSGEAAPAQKDG-----IFKVMLVGES 155

  Fly  1017 GVGKTTL--TYQFTTSDYICAYDLSLDDDYGQKTVSVLVDNIETDLEIID-----------HPAC 1068
            ||||:||  |:.....|.....:...:|.|.::   ::||..|..|.:.|           ...|
Human   156 GVGKSTLAGTFGGLQGDSAHEPENPAEDTYERR---IMVDKEEVTLVVYDIWEQGDAGGWLRDHC 217

  Fly  1069 EMSTEAFCATYNIDLFVVVYSVIDRNTFAAAERVLQYLKENEMLLSRGAILVANKTDLQRHRVVT 1133
            ..:.:|         |::|:||.||.:|:.....|..|:..........|||.||:||.|.|.|:
Human   218 LQTGDA---------FLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVS 273

  Fly  1134 RQMGRKVAKEIACKFIETSSGLDHNVDELLVGIVAQVKLNPQR 1176
            .:.||.:|..::||.||||:.|.||..||..|.|.|::|...|
Human   274 LEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGR 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42541	NP_996345.3	RGK	1008..>1175	CDD:206715	57/179 (32%)
		small_GTPase	1008..1171	CDD:197466	56/175 (32%)
REM2	XP_016876547.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D301527at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45775
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920