Protein Alignment CG42541 and Rgk1

DIOPT Version :9

• Sequence 1: NP_996345.3
• Gene: CG42541 / 31344
• FlyBaseID: FBgn0260658
• Length: 1418
• Species: Drosophila melanogaster
• Sequence 2: NP_725875.3
• Gene: Rgk1 / 14462605
• FlyBaseID: FBgn0264753
• Length: 1379
• Species: Drosophila melanogaster
• Alignment Length: 1394
• Identity: 315/1394 - (22%)
• Similarity: 498/1394 - (35%)
• Gaps: 428/1394 - (30%)

  Fly    67 SGGDRSDRRGRTERQYQQQIQNHHHHHQQQQQQQQQHQQQQQHQGAQQQ---------------- 115
            :.|.|||:..:..|.....        |.|.|.|.|.|.|..|.||.::
  Fly   141 TSGGRSDKSPQAPRAASPA--------QSQSQSQSQSQSQSPHPGATRRLSNASSLPSNVSRSKP 197

  Fly   116 ---------------RVFQSRSRSGSGSSVDLYANRNVSFSTTTNRV--NSLRRNRSRGSLTTLS 163
                           .:|...|.| |||..|.::....|.:|...|:  .|.|..:::.:.:|.|
  Fly   198 STPTATRAAAQLNGSGLFSGGSNS-SGSDNDGFSASGSSAATALRRLYFKSGRSIKNKINASTTS 261

  Fly   164 SNGLNALGLGPVTLAPNVSSSSSGSVLDLTLPGGTGTGTVDGGGGGGGGGAGCGGQNVYPSPAKS 228
            |..||.|.|.||:.|  ..:|..|.:.::|..||.....|.|                     .|
  Fly   262 STPLNGLPLNPVSSA--YHNSVGGPMHNMTTAGGVPKLVVMG---------------------TS 303

  Fly   229 NLKPALKATNSSVDRGCALFVGVDGEFHCGHIKYCSLHHDNFADGLQQLQQQLKNQQLGSGQKHV 293
            :........|:|.|..|.|...|.   |....:.|        |.|........::.|.|..:..
  Fly   304 SASIPDTTINTSTDSACTLITNVT---HTDTSETC--------DSLDMGDNSCPSEPLFSSLEEP 357

  Fly   294 TMACC------ECVCGSGKAARSGPDGEDNCGANYLKGYSGGYMLPPTPKGKSIDKTSTFTSAEL 352
            .:...      |...|.| ..|.|.:|.   ||..|: .:.....||.|
  Fly   358 LLTAVHIDSEHEGFGGMG-GGRGGANGR---GATELE-LTSCSRYPPRP---------------- 401

  Fly   353 AASKNKDLQERQERQEKRGSVILERAFDFDASCDESDS----ISSSTHNPVPSPAPHQLAYNVLK 413
                :.:||:..|.||...|::          ..|..|    :||...:|....:|.
  Fly   402 ----DMNLQDSVESQESCLSIL----------TGEPSSTTPLLSSQRRHPTGGHSPG-------- 444

  Fly   414 PILKQPQQQQQQKAMLQ----------AQHQQVNVQQHQGVTQQQYQQATH---QQLGNQQHQVV 465
               .|.|::::::...:          .:|...:..|.....:...:..:|   :..||:..:..
  Fly   445 ---SQRQEERRERKEREPSTAPPPTRIREHFTFDPPQSPKSARSSEKSTSHFSFKNYGNESAKDA 506

  Fly   466 THQPHQQVTHQQHPGGGVHQ-----QHQVMVAHQA------HAHTQVSNQQPVLQVQLPTPGVHV 519
            .....:........|||...     .:.||.|.:.      .:...:.|:...|:.:...|. |:
  Fly   507 GVGSGKGTGSGAGVGGGGGSGSGVGGNGVMAASEGDEEDDERSGDSIGNRSKKLRPRERDPN-HI 570

  Fly   520 VHRLLPTPPTHSGKGAYHTRETALQRVQQQS---------GYYNQGPSTSASAYGYNQAMEQQQM 575
            ...:.|:          |:|..:.:|.::::         ...:..|.|...|..:..:.:|:|.
  Fly   571 SPSVSPS----------HSRRASPKREKRRTTPIASTGAISKVSSAPPTMKDANFFGSSGKQKQR 625

  Fly   576 QQQLHYDPHQELQFEQHQPHQSHQQ---------------------------QQLQHQ------- 606
            |.| :..|||.....|.:.:.|...                           :::|.:
  Fly   626 QSQ-NIPPHQLSPSSQQRKYSSSSSSGSSERCLREATGPGTMFPFDREALDYERIQRECFAPSST 689

  Fly   607 -----QQHQLQHQQQHQQQ------QQYQQQQHQQQQHQQYADDTELDYDTEWELDEEPAPQIVP 660
                 ...:.::...::::      |||.:..||:|..|.|.:      ..:||.|..|
  Fly   690 TASNSSDSEAENCSVYERKSGADIFQQYSRLSHQEQLQQHYQE------PRDWERDRPP------ 742

  Fly   661 PLTTFNDFVNAAQNPTGSRQSLRAQKSPILNRRRASSIAGNLLHSDYTYTRNSIGGAPIDSNDFQ 725
                             ||::.:        |.|..|:....:..:..|..        .|:.|.
  Fly   743 -----------------SRKNSK--------RIRPDSVIHTTIRENQQYVP--------QSDAFY 774

  Fly   726 RISHSSSARDRMSLAGVLTFQQAIS--GAVSPQYGTVG--------SLNSQVPATG--EAGKPG- 777
            ..:.|||:....|.|.:..|:...|  ..:.|::|:|.        :|:.::|:.|  .|..|.
  Fly   775 PQAKSSSSPSDHSYAELNKFEDIASKFEQIPPKHGSVSGSGSGSLLNLHHKMPSPGSESAVSPTD 839

  Fly   778 --------------------IVGSDGIGGGGGGLPGGSSHNLNLTVGLGFLGGSSTTLAAVAE-- 820
                                |...|..|...|..|      :|:|       .:....|||.:
  Fly   840 SARRRSFKNKQRHQKEEHFYIQTEDRSGTAAGNGP------INVT-------ANPLEAAAVCKQP 891

  Fly   821 ----VTSGPD-------------GNGDSTDSPSPVSMIPSNQQKQQ------------------- 849
                |...|.             ..||.........::...:..||
  Fly   892 RATIVVQQPSLSLDNTVETLLIKNEGDFISVEQGKELVARKRNSQQLAHPPAHLHHHTQNHAHNH 956

  Fly   850 --QQLLQLQLQQEQQHLPTHLPMKRERGVGESSGASTSGTAIAELASSVVLATQSGKPMTERQR- 911
              .|..|.|.||:|||       ||:..:.:.... |:...|.||..   ...:.|.|...|.:
  Fly   957 HTLQQQQHQQQQQQQH-------KRDENMRQLLDV-TNTLTIEELRD---FQMRYGSPHHSRSQS 1010

  Fly   912 -----LRTSSMPAE----SRRPRLAEMRRSAIHAGDPDMTYYRLRSFSITSHGICNLGDSLRSRR 967
                 .|.|..|.:    .:|.|:|.|..:.:     :..|||||.||||..|:.|.||||:|||
  Fly  1011 VKMPGSRASGRPNQLCLPQQRSRVASMPNTGV-----EEEYYRLRHFSITGKGVVNRGDSLKSRR 1070

  Fly   968 SRSINSVTSTGTSN------------SGVDRHNSNASGASGEVIDGDPNVPAYKIAMLGASGVGK 1020
            |||.|||.|:.:|.            :.|....|.||  |.|....:|....|::.|||...|||
  Fly  1071 SRSNNSVASSNSSTEHLTTQQQLSAPASVSARTSLAS--SRESSTSNPGNGPYRVLMLGGPAVGK 1133

  Fly  1021 TTLTYQFTTSDYICAYDLSLDDDYGQKTVSVLVDNIETDLEIIDHPACEMSTEAFCATYNIDLFV 1085
            ::|..||.||:|:.|||.|:||:.|:|.||||:...|::|..|||...||:.:.....|:...:.
  Fly  1134 SSLVSQFMTSEYLHAYDTSIDDESGEKAVSVLLSGEESELIFIDHGYTEMTPDECLTNYDPHGYC 1198

  Fly  1086 VVYSVIDRNTFAAAERVLQYLKENEMLLSRGAILVANKTDLQRHRVVTRQMGRKVAKEIACKFIE 1150
            |:||..||::|:.||:|||.|..|:.:..:..|||:||.||.|.|:||.:.|:.:|....|||||
  Fly  1199 VIYSAADRSSFSVAEQVLQVLWTNQNIAQKAVILVSNKADLARSRLVTSEEGKAMATAYDCKFIE 1263

  Fly  1151 TSSGLDHNVDELLVGIVAQVKL---NPQRLRLL--------------TELELQRLN--------- 1189
            ||.|::|||||||||:::|::|   ||::.|.|              :.|....||
  Fly  1264 TSVGINHNVDELLVGLLSQIRLKLENPEKSRDLFRKRSIRKSKRRACSPLNAGCLNANTPLGPLG 1328

  Fly  1190 ---------LQSTIQKHRGMHLQTRRMVR 1209
                     .||:.:|:||....|...|:
  Fly  1329 EAVATPPGSAQSSPRKYRGSRTSTSLKVK 1357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42541	NP_996345.3	RGK	1008..>1175	CDD:206715	79/169 (47%)
		small_GTPase	1008..1171	CDD:197466	77/162 (48%)
Rgk1	NP_725875.3	DUF2967	459..715	CDD:288079	32/267 (12%)
		P-loop_NTPase	1121..1379	CDD:304359	92/237 (39%)
		small_GTPase	1121..1286	CDD:197466	77/164 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I4492
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D301527at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8675
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45775
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.020