DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2930 and AT1G68570

DIOPT Version :9

Sequence 1:	NP_001284845.1	Gene:	CG2930 / 31341	FlyBaseID:	FBgn0028491	Length:	815	Species:	Drosophila melanogaster
Sequence 2:	NP_177024.1	Gene:	AT1G68570 / 843186	AraportID:	AT1G68570	Length:	596	Species:	Arabidopsis thaliana

Alignment Length:	792	Identity:	163/792 - (20%)
Similarity:	266/792 - (33%)	Gaps:	314/792 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 ETNDFKNVSETEGQQKKLP-YPK----SVFFIISNEFCERFNYYGMRTVLVLYLSRVLGYSDDTA 169
            |......:||.|.|....| .||    ::.||.:||.||:....|....::.||:..|......|
plant     2 EEQSKNKISEEEKQLHGRPNRPKGGLITMPFIFANEICEKLAVVGFHANMISYLTTQLHLPLTKA 66

  Fly   170 TVVFHIFTMFVYFLCVFGAIISDSWLGKFKTILYLSLVYICGSVLLTLGAIGPLNLP-------- 226
            ......|........:.||.|:||:.|:|.||.:.|::|..|..|||:.||.|...|
plant    67 ANTLTNFAGTSSLTPLLGAFIADSFAGRFWTITFASIIYQIGMTLLTISAIIPTLRPPPCKGEEV 131

  Fly   227 -----METFTMLGLALI--ALGSGGIKPCVSAFGGDQF--KVPEQVKQITSFFSLFYFSINAGSL 282
                 ....::|.:||:  |||||||:|||.|||.|||  ..|.|..:..::|:.:||.:.|..|
plant   132 CVVADTAQLSILYVALLLGALGSGGIRPCVVAFGADQFDESDPNQTTKTWNYFNWYYFCMGAAVL 196

  Fly   283 ISTTVTPILREDVSCFDDINCYPLAFGVPAVLMIVSVIIFVLGRSLYKMKPPAGN---------- 337
            ::.||...::::|.       :.|..|:|.|.|.:|||.||.|..||:...|||:
plant   197 LAVTVLVWIQDNVG-------WGLGLGIPTVAMFLSVIAFVGGFQLYRHLVPAGSPFTRLIQVGV 254

  Fly   338 --------MVVLVSSTIW--------------------------TALTTKCKEKKTNPRE---HW 365
                    .:|...|.::                          .|:.|  :|....|.:   ||
plant   255 AAFRKRKLRMVSDPSLLYFNDEIDAPISLGGKLTHTKHMSFLDKAAIVT--EEDNLKPGQIPNHW 317

  Fly   366 -LDYADKKYDRQLIDDVKVLMR--------VLFLYLPLPVFWALFDQQGSRWTFQATRMDGDM-G 420
             |....:      ::::|.::|        :|.:        ..:.|||:....||..|:..: .
plant   318 RLSTVHR------VEELKSVIRMGPIGASGILLI--------TAYAQQGTFSLQQAKTMNRHLTN 368

  Fly   421 SWDIKPDQLQVLNPLLILIFIPLYD-VALYPALKLVGIRRP---LQKLTMGGILAGIAFIISGVV 481
            |:.|....:.|...:.:|..|..|| |.:..|.|..|:.|.   |.::.:|.:::.||.:::|.|
plant   369 SFQIPAGSMSVFTTVAMLTTIIFYDRVFVKVARKFTGLERGITFLHRMGIGFVISIIATLVAGFV 433

  Fly   482 ELSLEKTYPDLPYSQNIQLRIFNADNCDYFFTSNIPGAENVTVTSLNAYTNKDIYAPGSLDVEFS 546
            |:..:                                                     |:.:|..
plant   434 EVKRK-----------------------------------------------------SVAIEHG 445

  Fly   547 LSSASEACTISADKIPKVLTDNTAWSLFLNPLNGSGYYWEEDFVDKPSQSHPLIRNVANVPQELS 611
            |                                          :|||   |.::
plant   446 L------------------------------------------LDKP---HTIV----------- 454

  Fly   612 IRWEKASTGEVVYDDLASKTLLTRVNSAEYVVMVGERNVGTFDVHTGGVYTLLIKDNNNIYEANL 676

plant   455 ----------------------------------------------------------------- 454

  Fly   677 EEVTSPNSVKILWLVPQYVVMTLGEVMFSVTGLEFSYAQAPPSMKSVLQACWLLTVAFGN-VIVV 740
                   .:..|||:|||.:..:.|...|:..|||.|.|||.||:|...|.:.:.::.|| |..:
plant   455 -------PISFLWLIPQYGLHGVAEAFMSIGHLEFFYDQAPESMRSTATALFWMAISIGNYVSTL 512

  Fly   741 VIAEAALFESQAS---------------EFF--LFAGLMFADMLIFMVMA--YYYVP-------N 779
            ::.....|.::..               |:|  |...|...:::.::..|  |.|.|       .
plant   513 LVTLVHKFSAKPDGSNWLPDNNLNRGRLEYFYWLITVLQAVNLVYYLWCAKIYTYKPVQVHHSKE 577

  Fly   780 DPNKVEEAQPLT 791
            |.:.|:|...|:
plant   578 DSSPVKEELQLS 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2930	NP_001284845.1	2A1704	145..776	CDD:273343	143/728 (20%)
CG2930	NP_001284845.1	PTR2	198..504	CDD:279226	95/383 (25%)
AT1G68570	NP_177024.1	MFS_NPF3	27..564	CDD:340973	148/740 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	120	1.000	Domainoid score	I1880
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I1193
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.880