DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2930 and GTR2

DIOPT Version :9

Sequence 1:	NP_001284845.1	Gene:	CG2930 / 31341	FlyBaseID:	FBgn0028491	Length:	815	Species:	Drosophila melanogaster
Sequence 2:	NP_201074.1	Gene:	GTR2 / 836389	AraportID:	AT5G62680	Length:	616	Species:	Arabidopsis thaliana

Alignment Length:	773	Identity:	144/773 - (18%)
Similarity:	266/773 - (34%)	Gaps:	293/773 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 ELAETNDFKN---------------VSETEGQQKKLPYP--KSVFFIISNEFCERFNYYGMRTVL 154
            ||..|::.:|               |.|....|||:.|.  |.:.|||.||..|:....|..:.|
plant     7 ELESTDNHQNPSSAVYGGSVTAVDSVEEDVQNQKKVVYRGWKVMPFIIGNETFEKLGIIGTLSNL 71

  Fly   155 VLYLSRVLGYSDDTATVVFHIFTMFVYFLCVFGAIISDSWLGKFKTILYLSLVYICGSVLLTLGA 219
            ::||:.|......||..:.:.|:..:.|.....|.:.|::.|::||:....:....||.::.|.|
plant    72 LVYLTAVFNLKSITAATIINAFSGTINFGTFVAAFLCDTYFGRYKTLSVAVIACFLGSFVILLTA 136

  Fly   220 IGPLNLPME-----------------TFTMLGLALIALGSGGIKPCVSAFGGDQF--KVPEQVKQ 265
            ..|...|..                 .|.::||..:.:|:|||:||..|||.|||  |.....:.
plant   137 AVPQLHPAACGTAADSICNGPSGGQIAFLLMGLGFLVVGAGGIRPCNLAFGADQFNPKSESGKRG 201

  Fly   266 ITSFFSLFYFSINAGSLISTTVTPILREDVSCFDDINCYPLAFGVPAVLMIVSVIIFVLGRSLYK 330
            |.|||:.::|:.....::|.|:...::.:||       :.:...:|||||.::.:||..|..||.
plant   202 IDSFFNWYFFTFTFAQILSLTLVVYVQSNVS-------WTIGLTIPAVLMFLACLIFFAGDKLYV 259

  Fly   331 MKPPAGNMVVLVSSTIWTALTTKCKEKKTNP-REHWLD--------YADKKY------------- 373
            ....:|:.:..::..|..|:    |::...| ::.||:        ||:.|.
plant   260 KIKASGSPLAGIAQVIAVAI----KKRGLKPAKQPWLNLYNYYPPKYANSKLKYTDQFRFLDKAA 320

  Fly   374 -----DR----------------QLIDDVKVLMRVLFLYLPLPVFWALFDQQGSRWTFQATRMDG 417
                 |:                |.:::||.::|||.::....:::....||.:...|||.:.|.
plant   321 ILTPEDKLQPDGKPADPWKLCTMQQVEEVKCIVRVLPIWFASSIYYLTITQQMTYPVFQALQSDR 385

  Fly   418 DMGSWD-IKPDQLQVLNPLL-ILIFIPLYDVALYPALKLV-----GIRRPLQKLTMGGILAGIAF 475
            .:||.. :.|....|:..:. :.:||.:||..|.|.::.:     ||.. ||::..|...|..:.
plant   386 RLGSGGFVIPAATYVVFLMTGMTVFIVVYDRVLVPTMRRITGLDTGITL-LQRIGTGIFFATASL 449

  Fly   476 IISGVVELSLEKTYPDLPYSQNIQLRIFNADNCDYFFTSNIPGAENVTVTSLNAYTNKDIYAPGS 540
            :::|.|| ...:|:
plant   450 VVAGFVE-ERRRTF--------------------------------------------------- 462

  Fly   541 LDVEFSLSSASEACTISADKIPKVLTDNTAWSLFLNPLNGSGYYWEEDFVDKPSQSHPLIRNVAN 605
                                   .||                         ||:        :..
plant   463 -----------------------ALT-------------------------KPT--------LGM 471

  Fly   606 VPQELSIRWEKASTGEVVYDDLASKTLLTRVNSAEYVVMVGERNVGTFDVHTGGVYTLLIKDNNN 670
            .|::          ||:
plant   472 APRK----------GEI------------------------------------------------ 478

  Fly   671 IYEANLEEVTSPNSVKILWLVPQYVVMTLGEVMFSVTGLEFSYAQAPPSMKSVLQACWL----LT 731
                        :|:..:||:||..:..:.|...::..:||.|.|.|.:|:|...:.:.    ::
plant   479 ------------SSMSAMWLIPQLSLAGVAEAFAAIGQMEFYYKQFPENMRSFAGSIFYVGGGVS 531

  Fly   732 VAFGNVIVVVIAEAALFESQAS-------------EFFLFAGLMFADMLIFMVMAYYY 776
            ...|:.::..:.......|..:             .:|:.||::..:...|:||:.:|
plant   532 SYLGSFLIATVHRTTQNSSGGNWLAEDLNKGRLDLFYFMIAGILAVNFAYFLVMSRWY 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2930	NP_001284845.1	2A1704	145..776	CDD:273343	126/716 (18%)
CG2930	NP_001284845.1	PTR2	198..504	CDD:279226	86/374 (23%)
GTR2	NP_201074.1	MFS_NPF1_2	50..589	CDD:340974	132/728 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	120	1.000	Domainoid score	I1880
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I1193
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.880