DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2930 and AT3G53960

DIOPT Version :9

Sequence 1:	NP_001284845.1	Gene:	CG2930 / 31341	FlyBaseID:	FBgn0028491	Length:	815	Species:	Drosophila melanogaster
Sequence 2:	NP_190964.2	Gene:	AT3G53960 / 824563	AraportID:	AT3G53960	Length:	602	Species:	Arabidopsis thaliana

Alignment Length:	574	Identity:	133/574 - (23%)
Similarity:	245/574 - (42%)	Gaps:	105/574 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 NGKEPDQNDKEPDQNGKELAETNDFKNVSETEGQQKKLPYPKSVFFIISNEFCERFNYYGMRTVL 154
            |..:.:..|...||....|..:.|.:.......|....   ::..|||..||.||.:|:|:.|.|
plant     4 NKVDTEPQDSYDDQQKWVLDSSTDSRGEIPLRAQTGAW---RAALFIIGIEFSERLSYFGISTNL 65

  Fly   155 VLYLSRVLGYSDDTATVVFHIFTMFVYFLCVFGAIISDSWLGKFKTILYLSLVYICGSVLLTLG- 218
            |:||:.:|......|....:.::.....:.:.|..::|::||::.|:|..:.:|:.|.:||||.
plant    66 VVYLTTILHQDLKMAVKNTNYWSGVTTLMPLLGGFVADAYLGRYGTVLLATTIYLMGLILLTLSW 130

  Fly   219 ------------AIGPLNLPMETFTMLGLALIALGSGGIKPCVSAFGGDQFK--VPEQVKQITSF 269
                        .:.|.......| .:.:.||::|:||.||.:.:||.|||:  .||:.|...|:
plant   131 FIPGLKACHEDMCVEPRKAHEIAF-FIAIYLISIGTGGHKPSLESFGADQFEDGHPEERKMKMSY 194

  Fly   270 FSLFYFSINAGSLISTTVTPILREDVSCFDDINCYPLAFGVPAVLMIVSVIIFVLGRSLYKMKPP 334
            |:.:...:.||.|.:.||...:.:.:.       :.:|..:..::|..|..||.:|:..|:.:.|
plant   195 FNWWNAGLCAGILTAVTVIVYIEDRIG-------WGVASIILTIVMATSFFIFRIGKPFYRYRAP 252

  Fly   335 AGN-----MVVLVS------------STIWTALT----TKCKEKKTNPREHWLDYA--------D 370
            :|:     :.|.|:            |::...||    ||.:...::....:||.|        :
plant   253 SGSPLTPMLQVFVAAIAKRNLPCPSDSSLLHELTNEEYTKGRLLSSSKNLKFLDKAAVIEDRNEN 317

  Fly   371 KKYDRQ---------LIDDVKVLMRVLFLYLPLPVFWALFDQQGSRWTFQATRMDGDM--GSWDI 424
            .|.::|         .:::||:|:.::.::.....|.....|..:.:..||..||..:  .|:.:
plant   318 TKAEKQSPWRLATVTKVEEVKLLINMIPIWFFTLAFGVCATQSSTLFIKQAIIMDRHITGTSFIV 382

  Fly   425 KPDQLQVLNPLLILIFIPLYDVALYPAL-KLVGIRRP---LQKLTMGGILAGIAFIISGVVELSL 485
            .|..|..|..|.|:|.:.:|:..|.|.| :..|..|.   ||::.:|.:.:..|.||:.::|..
plant   383 PPASLFSLIALSIIITVTIYEKLLVPLLRRATGNERGISILQRIGVGMVFSLFAMIIAALIEKK- 446

  Fly   486 EKTYPDLPYSQNIQLR-------IFNADNCDYFFTSNIPGAENVTVTSLNAYTNKDIYAPG---S 540
                 .|.|::...:.       |:.|..   |....:  |:..|:..|..|....:  |.   |
plant   447 -----RLDYAKEHHMNKTMTLSAIWLAPQ---FLVLGV--ADAFTLVGLQEYFYDQV--PDSMRS 499

  Fly   541 LDVEFSLSSASEACTIS------ADKIPKVLTDNTAWSLFLNPLNGS---GYYW 585
            |.:.|.||....|..::      :|.:.:.:: ...|  |...||.|   .:||
plant   500 LGIAFYLSVLGAASFVNNLLITVSDHLAEEIS-GKGW--FGKDLNSSRLDRFYW 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2930	NP_001284845.1	2A1704	145..776	CDD:273343	119/519 (23%)
CG2930	NP_001284845.1	PTR2	198..504	CDD:279226	85/371 (23%)
AT3G53960	NP_190964.2	MFS	109..536	CDD:304372	100/450 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	120	1.000	Domainoid score	I1880
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I1193
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.880