DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2930 and AT3G25260

DIOPT Version :9

Sequence 1:	NP_001284845.1	Gene:	CG2930 / 31341	FlyBaseID:	FBgn0028491	Length:	815	Species:	Drosophila melanogaster
Sequence 2:	NP_189163.1	Gene:	AT3G25260 / 822120	AraportID:	AT3G25260	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	567	Identity:	123/567 - (21%)
Similarity:	230/567 - (40%)	Gaps:	127/567 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 DQNDKEPDQNGKELAETNDFKNVSETEGQQKKLPYPKSVFFIISNEFCERFNYYGMRTVLVLYLS 159
            :..:|..|..|||.        :|...|.      .|:.|.....|..|...:....|..::|.:
plant     4 EMEEKFEDWRGKEA--------ISGKHGG------IKAAFIACVVETMENMVFLACSTNFMMYFT 54

  Fly   160 RVLGYSDDTATVVFHIFTMFVYFLCVFGAIISDSWLGKFKTILYLSLVYICGSVLLTLGA----I 220
            :.:.||...|..:...|....:.|.:||..::||:|.:|...:....:.:.|.::|||.|    :
plant    55 KSMNYSTPKAATMVTNFVGTSFLLTIFGGFVADSFLTRFAAFVLFGSIELLGLIMLTLQAHITKL 119

  Fly   221 GPL-----NLPMETFTMLGLALIALGSGGIKPCVSAFGGDQFKVPEQVKQITSFFSLFYFSINAG 280
            .|.     :.|..|....||..||:|.||:|..:.|.||||.....| :.|:.||:.::||:..|
plant   120 QPQGGKKPSTPQSTVLFTGLYAIAIGVGGVKGSLPAHGGDQIGTRNQ-RLISGFFNWYFFSVCLG 183

  Fly   281 SLISTTVTPILREDVSCFDDINCYPLAFGVPAVLMIVSVIIFVLGRSLYKMKPPAGNMVVLVSST 345
            ..::.|:...:.|::.       :..:|.:...::..::.:||.|..:|:.|.|||:.:..:.:.
plant   184 GFLAVTLMVWIEENIG-------WSSSFTISTAVLASAIFVFVAGCPMYRFKRPAGSPLTRIVNV 241

  Fly   346 IWTALTTKCK-----------EKKTNPREH-----WLDYA--DKKYDRQLIDDVKVLMRVLFLYL 392
            ..:|...:.:           ...|:...|     :|:.|  :.|.....:::.:.     ||.|
plant   242 FVSAARNRNRFVTDAEVVTQNHNSTDKSIHHNKFKFLNKAKLNNKISATQVEETRT-----FLAL 301

  Fly   393 PLPVFWALFDQQGSRWTFQATRMDGDMGSWDIKPDQLQVLN---------PLLILIFIPLY---- 444
             ||:|       ||  |.........||::.::  |..|.|         |:..|..|||.
plant   302 -LPIF-------GS--TIIMNCCVAQMGTFSVQ--QGMVTNRKLSRSFEIPVASLNAIPLLCMLS 354

  Fly   445 DVALYPALKLVGIR----------RPLQKLTMGGILAGIAFIISGVVELSLEKTYPDLPYSQNIQ 499
            .:|||   :|.|.|          ..|:::..|..|..|:..::.:||:..:..    ....||:
plant   355 SLALY---ELFGKRILSNSERSSSFNLKRIGYGLALTSISMAVAAIVEVKRKHE----AVHNNIK 412

  Fly   500 LRIFNADNCDYFFTSNIPGAENVTVTSLNAYTNKDIYAPGSLDVEFSLSSASEACTIS-----AD 559
            :.:|..:.  .|...::  ::.:||..:..:..::  :|.|:.   |:|:|...|:.:     :.
plant   413 ISVFWLEL--QFVMLSL--SDMLTVGGMLEFFFRE--SPASMR---SMSTALGWCSTAMGFFLSS 468

  Fly   560 KIPKVLTDNTAW----------SLF------LNPLNGSGY-YWEEDF 589
            .:.:|:...|.|          .||      ||.||...| :|.:.:
plant   469 VLVEVVNGITGWLRDDLNESRLELFYLVLCVLNTLNLFNYIFWAKRY 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2930	NP_001284845.1	2A1704	145..776	CDD:273343	112/517 (22%)
CG2930	NP_001284845.1	PTR2	198..504	CDD:279226	79/355 (22%)
AT3G25260	NP_189163.1	MFS	93..481	CDD:304372	91/428 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	120	1.000	Domainoid score	I1880
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I1193
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.870