DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2930 and PTR2

DIOPT Version :9

Sequence 1:	NP_001284845.1	Gene:	CG2930 / 31341	FlyBaseID:	FBgn0028491	Length:	815	Species:	Drosophila melanogaster
Sequence 2:	NP_178313.1	Gene:	PTR2 / 814735	AraportID:	AT2G02040	Length:	585	Species:	Arabidopsis thaliana

Alignment Length:	755	Identity:	163/755 - (21%)
Similarity:	268/755 - (35%)	Gaps:	276/755 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 QNGKELAETN--DFKN---VSETEGQQKKLPYPKSVFFIISNEFCERFNYYGMRTVLVLYLSRVL 162
            |..|..||..  ||..   :.|..|..|..|      ||:.||.|||..|||:...|:.||:..|
plant    19 QEVKLYAEDGSVDFNGNPPLKEKTGNWKACP------FILGNECCERLAYYGIAGNLITYLTTKL 77

  Fly   163 GYSDDTATVVFHIFTMFVYFLCVFGAIISDSWLGKFKTILYLSLVYICGSVLLTLGAIGPLNLPM 227
            ...:.:|......:....|...:.||:::|::.|::.||...|.:|..|...|||.|..|...|.
plant    78 HQGNVSAATNVTTWQGTCYLTPLIGAVLADAYWGRYWTIACFSGIYFIGMSALTLSASVPALKPA 142

  Fly   228 E------------TFTML--GLALIALGSGGIKPCVSAFGGDQFKVPEQVKQI--TSFFSLFYFS 276
            |            .:.|.  ||.|||||:||||||||:||.|||...:..:::  .|||:.||||
plant   143 ECIGDFCPSATPAQYAMFFGGLYLIALGTGGIKPCVSSFGADQFDDTDSRERVRKASFFNWFYFS 207

  Fly   277 INAGSLISTTVTPILREDVSCFDDINCYPLAFGVPAVLMIVSVIIFVLGRSLYKMKPPAGNMVVL 341
            ||.|:|:|:::...::|:       ..:.|.||:|.|.|.:::..|..|..||:.:.|.|:.:..
plant   208 INIGALVSSSLLVWIQEN-------RGWGLGFGIPTVFMGLAIASFFFGTPLYRFQKPGGSPITR 265

  Fly   342 VSSTIWTAL---TTKCKEKKT---------------NPREHWLD--YADK------------KYD 374
            :|..:..:.   :.|..|..|               ...||..|  |.||            .|.
plant   266 ISQVVVASFRKSSVKVPEDATLLYETQDKNSAIAGSRKIEHTDDCQYLDKAAVISEEESKSGDYS 330

  Fly   375 RQ-------LIDDVKVLMRVLFLYLPLPVFWALFDQQGSRWTFQATRMDGDMGSWDIKPDQLQVL 432
            ..       .::::|:|:|:..::....:|.|::.|..:.:..|...|:..:||:.:.|..|...
plant   331 NSWRLCTVTQVEELKILIRMFPIWASGIIFSAVYAQMSTMFVQQGRAMNCKIGSFQLPPAALGTF 395

  Fly   433 NPLLILIFIPLYDVALYP-ALKLVGIRR---PLQKLTMGGILAGIAFIISGVVELSLEKTYPDLP 493
            :...::|::||||..:.| |.|..|:.:   .:|::.:|..::.:....:.:||:
plant   396 DTASVIIWVPLYDRFIVPLARKFTGVDKGFTEIQRMGIGLFVSVLCMAAAAIVEI---------- 450

  Fly   494 YSQNIQLRIFNADNCDYFFTSNIPGAENVTVTSLNAYTNKDIYAPGSLDVEFSLSSASEACTISA 558
                |:|.:.|
plant   451 ----IRLHMAN------------------------------------------------------ 457

  Fly   559 DKIPKVLTDNTAWSLFLNPLNGSGYYWEEDFVDKPSQSHPLIRNVANVPQELSIRWEKASTGEVV 623

plant   458 ----------------------------------------------------------------- 457

  Fly   624 YDDLASKTLLTRVNSAEYVVMVGERNVGTFDVHTGGVYTLLIKDNNNIYEANLEEVTSPNSVKIL 688
                                                             :..|.|..:|..:.:|
plant   458 -------------------------------------------------DLGLVESGAPVPISVL 473

  Fly   689 WLVPQYVVMTLGEVMFSVTGLEFSYAQAPPSMKSVLQACWLLTVAFGNVIVVVIAEAALF----- 748
            |.:|||.::...||.:.:..|||.|.|:|.:|:|:..|..|||.|.||.:..:|.....:
plant   474 WQIPQYFILGAAEVFYFIGQLEFFYDQSPDAMRSLCSALALLTNALGNYLSSLILTLVTYFTTRN 538

  Fly   749 --ESQASE----------FFLFAGLMFADMLIFMVMAYYY 776
              |...|:          |:|.|||...:|.::...|..|
plant   539 GQEGWISDNLNSGHLDYFFWLLAGLSLVNMAVYFFSAARY 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2930	NP_001284845.1	2A1704	145..776	CDD:273343	145/706 (21%)
CG2930	NP_001284845.1	PTR2	198..504	CDD:279226	96/364 (26%)
PTR2	NP_178313.1	MFS_NPF8	45..579	CDD:340976	155/729 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	120	1.000	Domainoid score	I1880
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H38006
Inparanoid	1	1.050	222	1.000	Inparanoid score	I1193
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100318
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.780