Protein Alignment CG2930 and SLC15A4

DIOPT Version :9

• Sequence 1: NP_001284845.1
• Gene: CG2930 / 31341
• FlyBaseID: FBgn0028491
• Length: 815
• Species: Drosophila melanogaster
• Sequence 2: XP_016874280.1
• Gene: SLC15A4 / 121260
• HGNCID: 23090
• Length: 635
• Species: Homo sapiens
• Alignment Length: 741
• Identity: 135/741 - (18%)
• Similarity: 251/741 - (33%)
• Gaps: 305/741 - (41%)

  Fly   136 IISNEFCERFNYYGMRTVLVLYLSRV-LGYSDDTATVVFHIFTMFVYFLCVFGAIISDSWLGKFK 199
            ::..|..||..:||:.:.|||:|:.. ..:....|:....:|....|....||..::|:.||:.:
Human    40 VLLTELLERAAFYGITSNLVLFLNGAPFCWEGAQASEALLLFMGLTYLGSPFGGWLADARLGRAR 104

  Fly   200 TILYLSLVY------------------ICGSV-LLTLGAIGP--LNLPMETFTMLGLALIALGSG 243
            .||....:|                  :|||. ||...|.||  ........|..||.|:.||..
Human   105 AILLSLALYLLGMLAFPLLAAPATRAALCGSARLLNCTAPGPDAAARCCSPATFAGLVLVGLGVA 169

  Fly   244 GIKPCVSAFGGDQF-KVP-------------------------------------------EQVK 264
            .:|..::.||.||. :.|                                           :|||
Human   170 TVKANITPFGADQVSRAPARCPCPCPAPAQPQPLPLPQSLPLTAEGAPCPGGLLSSAEESRQQVK 234

  Fly   265 Q-----ITSFFSLFYFSINAGSLISTTVTPILREDVSCFDDINCYPLAFGVPAVLMIVSVIIFVL 324
            .     ...||:.||:|||.|:::|......::::||       :...:.:|.|.:.::.::|:.
Human   235 DRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNVS-------FVTGYAIPTVCVGLAFVVFLC 292

  Fly   325 GRSLYKMKPPAGNMVVLVSSTIWTALT-TKCKEKKTNPRE------------------------H 364
            |:|::..|||.|:    ..:.::..|| :.|.:|::..|:                        |
Human   293 GQSVFITKPPDGS----AFTDMFKILTYSCCSQKRSGERQSNGEGIGVFQQSSKQSLFDSCKMSH 353

  Fly   365 WLDYADKKYDRQLIDDVKVLMRVLFLYLPLPVFWALFDQQGSRWTFQATRMD-GDMGSWDIKPDQ 428
            ...:.::|     ::|||.|::::.::|.|..:|.::.|..:.:..|:..:. .::.:....|..
Human   354 GGPFTEEK-----VEDVKALVKIVPVFLALIPYWTVYFQMQTTYVLQSLHLRIPEISNITTTPHT 413

  Fly   429 -----LQVLNPLLILIFIPLYDVALYPALKLVGIRRPLQKLTMGGILAGIAFIISGVVELSLEKT 488
                 |.:.:.:|||:.|||.|..:.|.|:..|:
Human   414 LPAAWLTMFDAVLILLLIPLKDKLVDPILRRHGL------------------------------- 447

  Fly   489 YPDLPYS-QNIQLRIFNADNCDYFFTSNIPGAENVTVTSLNAYTNKDIYAPGSLDVEFSLSSASE 552
               ||.| :.|.:.:|                                         |.:.||..
Human   448 ---LPSSLKRIAVGMF-----------------------------------------FVMCSAFA 468

  Fly   553 ACTISADKIPKVLTDNTAWSLFLNPLNGSGYYWEEDFVDKPSQSHPLIRNVANVPQELSIRWEKA 617
            |..:.:.::                                           |:.:|.:|   ..
Human   469 AGILESKRL-------------------------------------------NLVKEKTI---NQ 487

  Fly   618 STGEVVYDDLASKTLLTRVNSAEYVVMVGERNVGTFDVHTGGVYTLLIKDNNNIYEANLEEVTSP 682
            :.|.|||                                               :.|:|
Human   488 TIGNVVY-----------------------------------------------HAADL------ 499

  Fly   683 NSVKILWLVPQYVVMTLGEVMFSVTGLEFSYAQAPPSMKSVLQACWLLTVAFGN-----VIVVVI 742
               .:.|.||||:::.:.|:..|:.||||:|:.||.||:|.:...:......|:     ::.:|.
Human   500 ---SLWWQVPQYLLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGVGSFVGSGLLALVS 561

  Fly   743 AEAALFESQASEFFLFAGLMFADMLI 768
            .:|..:.|..::|    |...|.:||
Human   562 IKAIGWMSSHTDF----GDKQASLLI 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2930	NP_001284845.1	2A1704	145..776	CDD:273343	132/732 (18%)
		PTR2	198..504	CDD:279226	78/407 (19%)
SLC15A4	XP_016874280.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100318
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.730