Protein Alignment CG2930 and Slc15a1

DIOPT Version :9

• Sequence 1: NP_001284845.1
• Gene: CG2930 / 31341
• FlyBaseID: FBgn0028491
• Length: 815
• Species: Drosophila melanogaster
• Sequence 2: NP_476462.2
• Gene: Slc15a1 / 117261
• RGDID: 621736
• Length: 710
• Species: Rattus norvegicus
• Alignment Length: 700
• Identity: 290/700 - (41%)
• Similarity: 423/700 - (60%)
• Gaps: 73/700 - (10%)

  Fly   129 YPKSVFFIISNEFCERFNYYGMRTVLVLYLSRVLGYSDDTATVVFHIFTMFVYFLCVFGAIISDS 193
            ||.|:|||:.|||||||:|||||.:||||....||:.||.:|.::|.|....|...:.||:|:||
  Rat    12 YPLSIFFIVVNEFCERFSYYGMRALLVLYFRNFLGWDDDLSTAIYHTFVALCYLTPILGALIADS 76

  Fly   194 WLGKFKTILYLSLVYICGSVLLTLGAI----------GPLNLPME-TFTMLGLALIALGSGGIKP 247
            ||||||||:.||:||..|..::::.:|          .|.|||:. ..:|:||||||||:|||||
  Rat    77 WLGKFKTIVSLSIVYTIGQAVISVSSINDLTDHDHDGSPNNLPLHVALSMIGLALIALGTGGIKP 141

  Fly   248 CVSAFGGDQFKVPEQVKQITSFFSLFYFSINAGSLISTTVTPILR-EDVSCFDDINCYPLAFGVP 311
            ||||||||||: ..|.||...|||:||.:||||||:||.:||||| :.........|||||||||
  Rat   142 CVSAFGGDQFE-EGQEKQRNRFFSIFYLAINAGSLLSTIITPILRVQQCGIHSQQACYPLAFGVP 205

  Fly   312 AVLMIVSVIIFVLGRSLYKMKPPAGNMVVLVSSTIWTALTTKCKEK-KTNP-REHWLDYADKKYD 374
            |.||.|::|:||||..:||...|.||::..|:..|..|:..:.:.: |..| ||||||:|.:|||
  Rat   206 AALMAVALIVFVLGSGMYKKFQPQGNIMGKVAKCIGFAIKNRFRHRSKAFPKREHWLDWAKEKYD 270

  Fly   375 RQLIDDVKVLMRVLFLYLPLPVFWALFDQQGSRWTFQATRMDGDMGSWDIKPDQLQVLNPLLILI 439
            .:||..:|::.:|:|||:|||:|||||||||||||.|||.|.|.:|:.:|:|||:|.:|.:||:|
  Rat   271 ERLISQIKMVTKVMFLYIPLPMFWALFDQQGSRWTLQATTMTGKIGTIEIQPDQMQTVNAILIVI 335

  Fly   440 FIPLYDVALYPALKLVGIR-RPLQKLTMGGILAGIAFIISGVVELSLEKTYPDLPYSQNIQLRIF 503
            .:|:.|..:||.:...|.. ..|:|:|:|..||.:||:::.:|::.::||.|..|....:|:::.
  Rat   336 MVPIVDAVVYPLIAKCGFNFTSLKKMTVGMFLASMAFVVAAIVQVEIDKTLPVFPSGNQVQIKVL 400

  Fly   504 NADNCD---YFFTSNIPGAENVTVTSL-----------NAYTNKDIYAPGSLDVEFSLSSASEAC 554
            |..|.|   ||     || :||||..:           :..|:.::.:|||..|          .
  Rat   401 NIGNNDMAVYF-----PG-KNVTVAQMSQTDTFMTFDVDQLTSINVSSPGSPGV----------T 449

  Fly   555 TISADKIPKVLTDNTAWSLFLNPLNGSGYY--WEEDFVDKPSQSHPLIRNVANVPQELSIRWEKA 617
            |::.:..|........|        |...|  .::....||.:....||.|:.:.:.::|:
  Rat   450 TVAHEFEPGHRHTLLVW--------GPNLYRVVKDGLNQKPEKGENGIRFVSTLNEMITIK---- 502

  Fly   618 STGEVVYDDL----ASKTLLTRVNSAEYVVMVGE------RNVGTFDVHTGGVYTLLIKD--NNN 670
            .:|: ||:::    ||..........:|.:...|      .:..:.::..|..||.:|:.  ::.
  Rat   503 MSGK-VYENVTSHSASNYQFFPSGQKDYTINTTEIAPNCSSDFKSSNLDFGSAYTYVIRSRASDG 566

  Fly   671 IYEANLEEVTSPNSVKILWLVPQYVVMTLGEVMFSVTGLEFSYAQAPPSMKSVLQACWLLTVAFG 735
            ..|....|...||:|.:...:|||.::|.|||:||||||||||:|||.:|||||||.||||||.|
  Rat   567 CLEVKEFEDIPPNTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAIG 631

  Fly   736 NVIVVVIAEAALFESQASEFFLFAGLMFADMLIFMVMAYYYVPNDPNKVE 785
            |:||:::|||..|:.|.:|:.|||.|:....:||.:||.:|...:|.::|
  Rat   632 NIIVLIVAEAGHFDKQWAEYVLFASLLLVVCIIFAIMARFYTYINPAEIE 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2930	NP_001284845.1	2A1704	145..776	CDD:273343	275/673 (41%)
		PTR2	198..504	CDD:279226	154/320 (48%)
Slc15a1	NP_476462.2	2A1704	28..672	CDD:273343	275/673 (41%)
		Extracellular domain (ECD). /evidence=ECO:0000250|UniProtKB:Q9JIP7	383..586		48/231 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	687..710

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	313	1.000	Domainoid score	I1257
eggNOG	1	0.900	-	-		E1_COG3104
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38006
Inparanoid	1	1.050	507	1.000	Inparanoid score	I1279
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D246723at33208
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	1	1.000	-	-		mtm9126
orthoMCL	1	0.900	-	-		OOG6_100318
Panther	1	1.100	-	-	O	PTHR11654
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840