Protein Alignment yin and Slc15a1

DIOPT Version :10

• Sequence 1: NP_001284844.1
• Gene: yin / 31340
• FlyBaseID: FBgn0265575
• Length: 780
• Species: Drosophila melanogaster
• Sequence 2: NP_444309.2
• Gene: Slc15a1 / 56643
• MGIID: 1861376
• Length: 709
• Species: Mus musculus
• Alignment Length: 723
• Identity: 271/723 - (37%)
• Similarity: 413/723 - (57%)
• Gaps: 106/723 - (14%)

  Fly    69 YPKSVAFIISNEFCERFNYYGMRTILVLYLTNKLGYNEETATVLFHTFTMLVYIFPLIGALIADG 133
            ||.|:.||:.|||||||:|||||.:||||..|.||:::..:|.::|||..|.|:.|::||||||.
Mouse    12 YPLSIFFIVVNEFCERFSYYGMRALLVLYFRNFLGWDDNLSTAIYHTFVALCYLTPILGALIADS 76

  Fly   134 WLGKYKTILYLSLVYSLGAMVVSFGAV------PLSGMPTK-----AVTVVGLLLIAIGTGGIKP 187
            ||||:|||:.||:||::|..|:|..::      ..:|.|..     |:::|||.|||:|||||||
Mouse    77 WLGKFKTIVSLSIVYTIGQAVISVSSINDLTDHDHNGSPDSLPVHVALSMVGLALIALGTGGIKP 141

  Fly   188 CVSAFGGDQFSLPAQSFQLAKFFSLFYFAINAGSLISTTFTPILRAD---VHCFGDQDCFSLAFG 249
            ||||||||||. ..|..|..:|||:||.|||.|||:||..|||||..   :|  ..|.|:.||||
Mouse   142 CVSAFGGDQFE-EGQEKQRNRFFSIFYLAINGGSLLSTIITPILRVQQCGIH--SQQACYPLAFG 203

  Fly   250 VPAILMIFSVIIFMAGKRLYRCQPPAGNMIFGVSRCIADAFKG-WQKRRHSEP-MESFLDYAKPT 312
            |||.||..::|:|:.|..:|:...|.||::..|::||..|.|. ::.|..:.| .|.:||:||..
Mouse   204 VPAALMAVALIVFVLGSGMYKKFQPQGNIMGKVAKCIGFAIKNRFRHRSKAYPKREHWLDWAKEK 268

  Fly   313 VGSRMVQETKCLGRILRLFLPFPVFWALFDQQGSRWTFQATRMDGNVLGFQIKPDQMQVVNPLLI 377
            ...|::.:.|.:.:::.|::|.|:|||||||||||||.|||.|:|.:...:|:|||||.||.:||
Mouse   269 YDERLISQIKMVTKVMFLYIPLPMFWALFDQQGSRWTLQATTMNGKIGAIEIQPDQMQTVNAILI 333

  Fly   378 LGFLPLFDYIIYPALARCGIR-RPLQKLTLGLLLAALGFFLSAGLEMKMEQAAYRATPIEPDMTH 441
            :..:|:.|.::||.:|:||.. ..|:|:|:|:.||::.|.::|.::::::    :..|:.|....
Mouse   334 VIMVPIVDAVVYPLIAKCGFNFTSLKKMTVGMFLASMAFVVAAIVQVEID----KTLPVFPGGNQ 394

  Fly   442 LRI------YNGMPCRYEISSAVVQTPRVIEPLNVWEDLSLQMTESKEY-TFNAQPVSGECPSII 499
            ::|      .|.|...:..:|..:                .||:::..: ||:           |
Mouse   395 VQIKVLNIGNNNMTVHFPGNSVTL----------------AQMSQTDTFMTFD-----------I 432

  Fly   500 DKLRL-------QPG-KSVSYFL-------------AQDKLVEFADGLQMAATDTGRTSVRALLN 543
            |||..       .|| .:|::..             :|.::|:  |||.. ..:.|...:| .:|
Mouse   433 DKLTSINISSSGSPGVTTVAHDFEQGHRHTLLVWNPSQYRVVK--DGLNQ-KPEKGENGIR-FVN 493

  Fly   544 TPDGEGPVLLS---TESATSQEPPLTLDKGNVPQLHRITPGFARVDINGKKVA-----SFEAKE- 599
            |.:....:.:|   .|:.||.         |.........|..:..||...||     .|::..
Mouse   494 TLNEMVTIKMSGKVYENVTSH---------NASGYQFFPSGEKQYTINTTAVAPTCLTDFKSSNL 549

  Fly   600 --GRLYSILVTGSARDGYQHNVIEVVALSTVSILWQLPQIVVMTAAEVMFSVTGLEFSYSQSPPS 662
              |..|:.::..::....:....|.:..:||::..|:||..::|..||:||||||||||||:|.:
Mouse   550 DFGSAYTYVIRRASDGCLEVKEFEDIPPNTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSN 614

  Fly   663 MKSVLQACWLLSVAIGNMLVVVIAEFKFTSSQSGEFTLFASLMLVDMMIFLWLARSYQYKDQRE- 726
            |||||||.|||:||:||::|:::|.......|..|:.|||||:||..:||..:||.|.|.:..|
Mouse   615 MKSVLQAGWLLTVAVGNIIVLIVAGAGHFPKQWAEYILFASLLLVVCVIFAIMARFYTYINPAEI 679

  Fly   727 --DFEDDD 732
              .|::|:
Mouse   680 EAQFDEDE 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yin	NP_001284844.1	2A1704	85..719	CDD:273343	255/689 (37%)
Slc15a1	NP_444309.2	2A1704	28..671	CDD:273343	255/689 (37%)
		Extracellular domain (ECD). /evidence=ECO:0000303|PubMed:26320580	383..585		42/245 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	690..709