Protein Alignment yin and Slc15a3

DIOPT Version :10

• Sequence 1: NP_001284844.1
• Gene: yin / 31340
• FlyBaseID: FBgn0265575
• Length: 780
• Species: Drosophila melanogaster
• Sequence 2: NP_647557.1
• Gene: Slc15a3 / 246239
• RGDID: 628663
• Length: 582
• Species: Rattus norvegicus
• Alignment Length: 738
• Identity: 146/738 - (19%)
• Similarity: 257/738 - (34%)
• Gaps: 275/738 - (37%)

  Fly    72 SVAFIISNEFCERFNYYGMRTILVLYLTNKLGYN-----EETATVLFHTFTMLVYIFPLIGALIA 131
            :.|.::..|..||..::|:.:.||||| |.|.:|     ...||:||...:   |:...:|..:|
  Rat    34 AAAAVLLVEMLERAAFFGVTSNLVLYL-NSLNFNWDGEHASRATLLFLGAS---YLLAPVGGWLA 94

  Fly   132 DGWLGKYKTI-----LYLSLVYSLGAMVVSFGAVPLSG----MPTK-----------------AV 170
            |.:||::..|     |||:....|...:...|.....|    :|.|                 |.
  Rat    95 DVYLGRFLAISLSLLLYLAATGLLLTTITDDGRRSFCGEMPELPLKPACPSANCQGSWSSPYCAT 159

  Fly   171 TV-VGLLLIAIGTGGIKPCVSAFGGDQ-FSLPAQSFQLAKFFSLFYFAINAGSLISTTFTPILRA 233
            |: :.|||:|:....::..:::||.|| ..|...:.:  :||:.||::||.|:::|......:..
  Rat   160 TLYLVLLLLALAASSVRSNLTSFGADQVMDLGRDATR--RFFNWFYWSINLGAILSLLVVAFIEQ 222

  Fly   234 DVHCFGDQDCFSLAFGVPAILMIFSVIIFMAGKRLYRCQPPAGNMIFGVSRCIADAFK----GWQ 294
            ::       .|...:.:...|:..:..||:....::..:||.|:.   ||..:..||:    |||
  Rat   223 NI-------SFLQGYSIIVGLVGLAFFIFLIATPVFITKPPTGSQ---VSSMLNLAFQNCCPGWQ 277

  Fly   295 -----KRRHSEPMESFLDYAKPTVGSRMVQETKCLGRILRLFLPFPV----FWALFDQQGSRWTF 350
                 ..|:||......|......|. ..||.....::|...||..|    :|.::.|..|.:..
  Rat   278 WWRRPSSRNSEGAHLLPDQRSNQPGP-SPQEDMANFQVLLKVLPVMVTLVPYWMVYFQMQSTYVL 341

  Fly   351 QAT--------RMDGNV--------LGFQIKPDQMQVVNPLLILGFLPLFDYIIYPALARCG-IR 398
            |..        |.:.|:        ..::|....:.:.|..:||..:|:.|::|.|.|.||. :.
  Rat   342 QGLHLHIPNIFRTNPNISLPLRSDSSNYRIPEAWLLLANVAVILILVPVKDHLIDPLLLRCKLLP 406

  Fly   399 RPLQKLTLGLLLAALGFFLSAGLEMKMEQAAYRATPIEPDMTHLRIYNGMPCRYEISSAVVQTPR 463
            ..|||:.||:.
  Rat   407 SALQKMALGMF------------------------------------------------------ 417

  Fly   464 VIEPLNVWEDLSLQMTESKEYTFNAQPVSGECPSIIDKLRLQPGKSVSYFLAQDKLVEFADGLQM 528
                                :.|.:..|:|    :::|.|||                     .:
  Rat   418 --------------------FGFTSIIVAG----VLEKERLQ---------------------YI 437

  Fly   529 AATDTGRTSVRALLNTPDGEGPVLLSTESATSQEPPLTLDKGNVPQLHRITPGFARVDINGKKVA 593
            ||..|                                      ||||            .||
  Rat   438 AANQT--------------------------------------VPQL------------IGK--- 449

  Fly   594 SFEAKEGRLYSILVTGSARDGYQHNVIEVVALSTVSILWQLPQIVVMTAAEVMFSVTGLEFSYSQ 658
                                       ::...:.:||.||:||.:::..:|:..|:.||||:||:
  Rat   450 ---------------------------DLYYAAPLSIWWQIPQYLLIGISEIFASIPGLEFAYSE 487

  Fly   659 SPPSMKSVLQACWLLSVAIGNM----LVVVIA---EFKFTSSQSGE---------FTLFASLMLV 707
            :|.||:..:...:.....:|::    ||.:::   .:.:.....|.         |.|.|.:..|
  Rat   488 APRSMQGAIMGIFFCLSGVGSLLGSGLVALLSLPGGWMYCPKDFGNINNCRMDLYFFLLAGIQAV 552

  Fly   708 DMMIFLWLARSYQYKDQREDFED 730
            ..::|||:|..|:...|..|.::
  Rat   553 TAVLFLWIAGRYERTRQDPDSQN 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yin	NP_001284844.1	2A1704	85..719	CDD:273343	139/712 (20%)
Slc15a3	NP_647557.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		MFS	38..563	CDD:475125	142/720 (20%)