Protein Alignment yin and SLC15A4

DIOPT Version :9

• Sequence 1: NP_001284844.1
• Gene: yin / 31340
• FlyBaseID: FBgn0265575
• Length: 780
• Species: Drosophila melanogaster
• Sequence 2: XP_016874280.1
• Gene: SLC15A4 / 121260
• HGNCID: 23090
• Length: 635
• Species: Homo sapiens
• Alignment Length: 787
• Identity: 139/787 - (17%)
• Similarity: 240/787 - (30%)
• Gaps: 338/787 - (42%)

  Fly    76 IISNEFCERFNYYGMRTILVLYLTNK----LGYNEETATVLFHTFTMLVYIFPLIGALIADGWLG 136
            ::..|..||..:||:.:.|||:|...    .|.....|.:||...|   |:....|..:||..||
Human    40 VLLTELLERAAFYGITSNLVLFLNGAPFCWEGAQASEALLLFMGLT---YLGSPFGGWLADARLG 101

  Fly   137 KYKTILYLSLVYSLGAMVVSFGAVPLSGMP-TKA-------------------------VTVVGL 175
            :.:.||....:|.||.:     |.||...| |:|                         .|..||
Human   102 RARAILLSLALYLLGML-----AFPLLAAPATRAALCGSARLLNCTAPGPDAAARCCSPATFAGL 161

  Fly   176 LLIAIGTGGIKPCVSAFGGDQFS-----------LPAQSFQL----------------------- 206
            :|:.:|...:|..::.||.||.|           .|||...|
Human   162 VLVGLGVATVKANITPFGADQVSRAPARCPCPCPAPAQPQPLPLPQSLPLTAEGAPCPGGLLSSA 226

  Fly   207 ---------------AKFFSLFYFAINAGSLISTTFTPILRADVHCFGDQDCFSLAFGVPAILMI 256
                           .:||:.||::||.|:::|......::.:|       .|...:.:|.:.:.
Human   227 EESRQQVKDRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNV-------SFVTGYAIPTVCVG 284

  Fly   257 FSVIIFMAGKRLYRCQPPAGNMIFGVSRCIADAFK-----------GWQKRRHSEPM-------- 302
            .:.::|:.|:.::..:||.|:       ...|.||           ..:::.:.|.:
Human   285 LAFVVFLCGQSVFITKPPDGS-------AFTDMFKILTYSCCSQKRSGERQSNGEGIGVFQQSSK 342

  Fly   303 ESFLDYAKPTVG----SRMVQETKCLGRILRLFLPFPVFWALFDQQGSRWTFQATRMD-GNVLGF 362
            :|..|..|.:.|    ...|::.|.|.:|:.:||....:|.::.|..:.:..|:..:. ..:...
Human   343 QSLFDSCKMSHGGPFTEEKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYVLQSLHLRIPEISNI 407

  Fly   363 QIKPDQ-----MQVVNPLLILGFLPLFDYIIYPALARCG-IRRPLQKLTLGLLLAALGFFLSAGL 421
            ...|..     :.:.:.:|||..:||.|.::.|.|.|.| :...|:::.:|:.......|.:..|
Human   408 TTTPHTLPAAWLTMFDAVLILLLIPLKDKLVDPILRRHGLLPSSLKRIAVGMFFVMCSAFAAGIL 472

  Fly   422 EMKMEQAAYRATPIEPDMTHLRIYNGMPCRYEISSAVVQTPRVIEPLNVWEDLSLQMTESKEYTF 486
            |.|.                                          ||:          .||.|.
Human   473 ESKR------------------------------------------LNL----------VKEKTI 485

  Fly   487 NAQPVSGECPSIIDKLRLQPGKSVSYFLAQDKLVEFADGLQMAATDTGRTSVRALLNTPDGEGPV 551
            | |.:
Human   486 N-QTI------------------------------------------------------------ 489

  Fly   552 LLSTESATSQEPPLTLDKGNVPQLHRITPGFARVDINGKKVASFEAKEGRLYSILVTGSARDGYQ 616
                              |||
Human   490 ------------------GNV-------------------------------------------- 492

  Fly   617 HNVIEVVALSTVSILWQLPQIVVMTAAEVMFSVTGLEFSYSQSPPSMKSVLQACWLLSVAIGNML 681
                 |...:.:|:.||:||.:::..:|:..|:.||||:||.:|.||:|.:...:
Human   493 -----VYHAADLSLWWQVPQYLLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLF---------- 542

  Fly   682 VVVIAEFKFTSSQSGEFTLFASLMLVDMMIFLWLARSYQYKDQREDFEDDDDATIDSVMQSKPKA 746
                    |..|..|.|.....|.||.:....|::       ...||.|...:.:  :..:||..
Human   543 --------FFFSGVGSFVGSGLLALVSIKAIGWMS-------SHTDFGDKQASLL--IPGAKPAL 590

  Fly   747 TTVDTTA 753
            .|....|
Human   591 ATAQRAA 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yin	NP_001284844.1	2A1704	85..719	CDD:273343	129/742 (17%)
		MFS	138..>398	CDD:304372	70/364 (19%)
SLC15A4	XP_016874280.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	1	Normalized mean entropy	S4805
OMA	1	1.010	-	-		QHG55282
OrthoDB	1	1.010	-	-		D365203at2759
OrthoFinder	1	1.000	-	-		FOG0000101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100318
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X63
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.780