Protein Alignment yin and slc15a2

DIOPT Version :10

• Sequence 1: NP_001284844.1
• Gene: yin / 31340
• FlyBaseID: FBgn0265575
• Length: 780
• Species: Drosophila melanogaster
• Sequence 2: XP_004917672.2
• Gene: slc15a2 / 100493689
• XenbaseID: XB-GENE-486968
• Length: 727
• Species: Xenopus tropicalis
• Alignment Length: 725
• Identity: 279/725 - (38%)
• Similarity: 434/725 - (59%)
• Gaps: 62/725 - (8%)

  Fly    64 TPPIP------YPKSVAFIISNEFCERFNYYGMRTILVLYLTNKLGYNEETATVLFHTFTMLVYI 122
            |..:|      ||.|:.||:.|||||||:||||:.:|.||..|.|.::|..:|.::|.|:.|.|.
 Frog    31 TKKVPKLCGTNYPLSIMFIVVNEFCERFSYYGMKAVLTLYFLNYLHWDENLSTTVYHAFSGLCYF 95

  Fly   123 FPLIGALIADGWLGKYKTILYLSLVYSLGAMVVSFGAVPLSGMPT--KAVTVVGLLLIAIGTGGI 185
            .|||||.|||.||||:.||.|||::|.:|.::.|.||:|..|...  .|::::||:.||.|||||
 Frog    96 TPLIGAPIADAWLGKFNTIFYLSILYVIGHVIKSVGAIPTVGSTEVHVALSIIGLIAIAFGTGGI 160

  Fly   186 KPCVSAFGGDQFSLPAQSFQLAKFFSLFYFAINAGSLISTTFTPILRADVHCFGDQDCFSLAFGV 250
            ||||:|||||||. ...:.:.:||||:||.:|||||||||..||:||.||.|||. ||::|||||
 Frog   161 KPCVAAFGGDQFE-EEHAQERSKFFSIFYLSINAGSLISTFVTPVLRGDVKCFGG-DCYALAFGV 223

  Fly   251 PAILMIFSVIIFMAGKRLYRCQPPAGNMIFGVSRCIADAFKG-WQKRRHSEP-MESFLDYAKPTV 313
            ||.||..::|:|:||..:|:..||.||::..|.|||..|.|. |:.|....| .|.:||:|:...
 Frog   224 PAALMFVALIVFVAGSGMYKKYPPQGNILASVFRCIGFALKNRWRHRSKQYPKREHWLDWAEEKF 288

  Fly   314 GSRMVQETKCLGRILRLFLPFPVFWALFDQQGSRWTFQATRMDGNVLGFQIKPDQMQVVNPLLIL 378
            ..|::.|.|.:.::|.|::|.|:|||||||||||||.|||||:.:..||.::|||:|::||||||
 Frog   289 QKRLITEVKMVTKVLFLYIPLPMFWALFDQQGSRWTLQATRMNSDFGGFVLQPDQIQILNPLLIL 353

  Fly   379 GFLPLFDYIIYPALARCGIR-RPLQKLTLGLLLAALGFFLSAGLEMKMEQAAYRATPI-EPDMTH 441
            ..:|:||..|||.:..|.|. :.:.|:.:|::||||.|.::..:|:|:.:.   ..|: :..:::
 Frog   354 ILIPIFDLCIYPLVRCCKIDFKAIPKMAIGMILAALAFAVATVVEIKINET---LPPVPKAQVSY 415

  Fly   442 LRIYN--GMPCRYEISS-AVVQTP-----RVIEPLNVWEDLSLQMTESKEYTFNAQ----PVSGE 494
            |::.|  |.....:|.. .:::.|     ..::|    :.:.|::|.:.. .|:|:    .|:.:
 Frog   416 LQVLNLAGGDVDVDIPGFEIIKQPSLYGANALDP----DYVKLELTTAHN-NFDAKLTVGAVTAD 475

  Fly   495 CPSIIDKLRLQPGKSVSYFLAQDKLVEFADGLQMAATD--TGRTSVRAL------LNTPDGEGPV 551
            ||     :.:|...|.|..:..|.|  ..|.::.:.|.  .|..:||.:      :|...||..|
 Frog   476 CP-----IHIQEKSSYSLLVYGDNL--NCDLIEESQTKPANGLAAVRFINMLNRDINVTIGESTV 533

  Fly   552 LLSTESATSQEPPLTLDKGNVPQLHRITPGFARVDINGKKVASFEAKEGRLYSILVTGSARDGYQ 616
              |.:......|.:|:.:|.:...:........:|:.   :.:|    |..||:::.....|..:
 Frog   534 --SAKGNNGVSPYITVKRGKITATYPAGAEQQELDLG---LLNF----GAAYSVILVRDLGDTIE 589

  Fly   617 HNVIEVVALSTVSILWQLPQIVVMTAAEVMFSVTGLEFSYSQSPPSMKSVLQACWLLSVAIGNML 681
            ....|.|:.::..:.||:||.|:::|.|||||||||||||||:|.||||||||.||.::||||::
 Frog   590 FKKTEDVSANSFHVAWQVPQYVLLSAGEVMFSVTGLEFSYSQAPISMKSVLQAGWLFTIAIGNVI 654

  Fly   682 VVVIAEFKFTSSQSGEFTLFASLMLVDMMIFLWLARSYQYKDQREDFEDDDDATIDSVMQSKPKA 746
            |:::|: ..:.:|..||.|||:|::...:||..:...| .....:|.:::::.....:.:.:|.|
 Frog   655 VLIVAQ-AGSLAQWAEFILFAALLVAVCIIFSIMGYFY-VPANPDDLKEEEELEKKQLPEGEPSA 717

  Fly   747 TTVDTTARKT 756
            ..::  .|||
 Frog   718 IPME--ERKT 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yin	NP_001284844.1	2A1704	85..719	CDD:273343	259/659 (39%)
slc15a2	XP_004917672.2	2A1704	58..691	CDD:273343	259/659 (39%)