Protein Alignment yin and slc15a4

DIOPT Version :10

• Sequence 1: NP_001284844.1
• Gene: yin / 31340
• FlyBaseID: FBgn0265575
• Length: 780
• Species: Drosophila melanogaster
• Sequence 2: XP_002935336.2
• Gene: slc15a4 / 100491217
• XenbaseID: XB-GENE-986485
• Length: 570
• Species: Xenopus tropicalis
• Alignment Length: 750
• Identity: 142/750 - (18%)
• Similarity: 272/750 - (36%)
• Gaps: 284/750 - (37%)

  Fly    61 GFETPPIPYPKSV--------AFIISNEFCERFNYYGMRTILVLYLTNKL----GYNEETATVLF 113
            |...||:| |.||        |.::.:|..||..:||:.:.|||:|..::    |.....|.:||
 Frog    15 GRSEPPVP-PGSVFAGRGLACAAVLLSELLERVAFYGITSNLVLFLNGQIFGWEGTQASQALLLF 78

  Fly   114 HTFTMLVYIFPLIGALIADGWLGKYKTILYLSLVYSLGAM---VVSF--------GAVP------ 161
            ...|.||  .|..|.| ||..||::..||...::|.||.:   ::|:        |.:|
 Frog    79 MGITYLV--SPFAGWL-ADALLGRFFIILGSMVLYLLGMLLFPMISYSGTRTAFCGDIPWARIDN 140

  Fly   162 -----LSGMPTKAV----------TVVGLLLIAIGTGGIKPCVSAFGGDQFSLPAQSFQLAKFFS 211
                 .|..|...:          ..:||:::.:|.|.:|..::.||.||....... ...:||:
 Frog   141 CSRSNTSSSPDTCLDPSRRYCAPAVFLGLIIVGLGVGSVKANITPFGADQVKDRGPE-ATRRFFN 204

  Fly   212 LFYFAINAGSLISTTFTPILRADVHCFGDQDCFSLAFGVPAILMIFSVIIFMAGKRLYRCQPPAG 276
            .||::||.|::||......::.:|.       |...:.:|.:.:..|.::|:.||.::..:|..|
 Frog   205 WFYWSINLGAIISLGGIAYVQQNVD-------FLTGYIIPTVCIGVSFLVFLCGKTVFVTKPADG 262

  Fly   277 NMIFGVSRCIADAFKGWQKRRHS---------EPMESFLDYAKPTVGSRM----VQETKCLGRIL 328
            :....:.:.:|.:....:.||.:         ...:|.||:||.:.|...    |::.|.|.:|:
 Frog   263 SAFTDMVKILAYSCCARKHRRENTRHVQNNQQRHKQSRLDFAKASRGGPFREDKVEDVKSLVKII 327

  Fly   329 RLFLPFPVFWALFDQQGSRWTFQATRMDGNVLGFQIKP----------DQMQVVNPLLILGFLPL 383
            .:||....:|.::.|..:.:..|:       |..:|.|          ..:.:.:.:|||..:||
 Frog   328 PVFLALIPYWTVYFQMQTTYVLQS-------LHLKIPPIFNNNHTLPAAWLTMFDAVLILILIPL 385

  Fly   384 FDYIIYPALARCG-IRRPLQKLTLGLLLAALGFFLSAGLEMKMEQAAYRATPIEPDMTHLRIYNG 447
            .|.::.|.|.:.| :..||:::.:|:      ||:...:
 Frog   386 KDKMVDPFLKKRGLLPSPLKRIAVGM------FFVMCSV-------------------------- 418

  Fly   448 MPCRYEISSAVVQTPRVIEPLNVWEDLSLQMTESKEYTFNAQPVSGECPSIIDKLRLQPGKSVSY 512
                  :::.::::.|            |::.::                  ||::.|.| .|:|
 Frog   419 ------LAAGILESKR------------LEIVKN------------------DKIQQQIG-GVTY 446

  Fly   513 FLAQDKLVEFADGLQMAATDTGRTSVRALLNTPDGEGPVLLSTESATSQEPPLTLDKGNVPQLHR 577
            :.|
 Frog   447 YAA-------------------------------------------------------------- 449

  Fly   578 ITPGFARVDINGKKVASFEAKEGRLYSILVTGSARDGYQHNVIEVVALSTVSILWQLPQIVVMTA 642
                                                             .:::.|||||.:::..
 Frog   450 -------------------------------------------------NLAVWWQLPQYILIGI 465

  Fly   643 AEVMFSVTGLEFSYSQSPPSMKSVLQACWLLSVAIGN------MLVVVIAEFKFTSSQSG----- 696
            :|:..|:.||||:||.:|.||:|.:...:.....||:      :.:|.|.:..:.|:.|.
 Frog   466 SEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGIGSFVGSGLLALVSIPQIGWMSNHSDLGNIN 530

  Fly   697 ------EFTLFASLMLVDMMIFLWLARSYQYKDQR 725
                  .|.|.|::....:::||.::..|:.:..|
 Frog   531 GCTLNYYFFLLAAVQAATLILFLIISVKYERQQSR 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yin	NP_001284844.1	2A1704	85..719	CDD:273343	129/710 (18%)
slc15a4	XP_002935336.2	MFS_SLC15A3_4	31..558	CDD:340906	133/724 (18%)