Protein Alignment yin and slc15a1

DIOPT Version :10

• Sequence 1: NP_001284844.1
• Gene: yin / 31340
• FlyBaseID: FBgn0265575
• Length: 780
• Species: Drosophila melanogaster
• Sequence 2: XP_012813171.2
• Gene: slc15a1 / 100145353
• XenbaseID: XB-GENE-987154
• Length: 727
• Species: Xenopus tropicalis
• Alignment Length: 741
• Identity: 275/741 - (37%)
• Similarity: 429/741 - (57%)
• Gaps: 88/741 - (11%)

  Fly    69 YPKSVAFIISNEFCERFNYYGMRTILVLYLTNKLGYNEETATVLFHTFTMLVYIFPLIGALIADG 133
            ||.|:.||:.|||||||:|||||.:||||....|.:::..|||::|||..:.|:.|::||:|||.
 Frog    29 YPLSIFFIVINEFCERFSYYGMRAVLVLYFKYFLHWDDNLATVIYHTFVAICYLTPILGAIIADS 93

  Fly   134 WLGKYKTILYLSLVYSLGAMVVSFGAV------PLSGMPTK-----AVTVVGLLLIAIGTGGIKP 187
            ||||:|||:|||:||::|.:|::..|:      ...|.|..     |::|:||||||:|||||||
 Frog    94 WLGKFKTIVYLSIVYTVGQVVMAVSAIHDLTDGNRDGTPDTLEVHVALSVIGLLLIALGTGGIKP 158

  Fly   188 CVSAFGGDQFSLPAQSFQLAKFFSLFYFAINAGSLISTTFTPILRAD---VHCFGDQDCFSLAFG 249
            ||:|||||||. ..|..|.::|||:||.:||||||:||..|||||..   :|  ..|.|:.||||
 Frog   159 CVAAFGGDQFE-ENQDKQRSQFFSIFYLSINAGSLLSTIITPILRGQECGIH--SQQKCYPLAFG 220

  Fly   250 VPAILMIFSVIIFMAGKRLYRCQPPAGNMIFGVSRCIADAFKG-WQKRRHSEP-MESFLDYAKPT 312
            |||.||:.::::|:.|..:|:...|.||:|..||:||..|.:. ::.|..|.| .|.:||:||..
 Frog   221 VPAALMVVALVVFIVGSSMYKKVSPQGNIIVKVSKCIGFAIRNRYRNRSKSIPKREHWLDWAKEK 285

  Fly   313 VGSRMVQETKCLGRILRLFLPFPVFWALFDQQGSRWTFQATRMDGNVLGFQIKPDQMQVVNPLLI 377
            ...|::.:.|.:.::|.|::|.|:|||||||||||||.|||.||||....||:|||||.|||:||
 Frog   286 YDERLIAQIKMVLKVLFLYIPLPMFWALFDQQGSRWTLQATTMDGNFGAIQIQPDQMQTVNPILI 350

  Fly   378 LGFLPLFDYIIYPALARCGIR-RPLQKLTLGLLLAALGFFLSAGLEMKMEQAAYRATPIEPDMT- 440
            :..:|:||..:||.:.:|.:. .||:::|:|:.|||:.|..:|.::::::    :..|..|...
 Frog   351 IVLVPIFDAAVYPLIRKCKLDFTPLKRMTVGMFLAAMAFVAAALVQIEID----KTLPTFPSSNE 411

  Fly   441 -HLRIYN----GMPCRYEISSAVVQTPRVIEPLNVWEDLSLQMTESKEYTFNAQ-PVSGECPSII 499
             .|::.|    .:...|..::|   ...:|.|....|..:|:.:.|..:.:... |.......:.
 Frog   412 FQLKVINLGTKDLNVTYVANTA---DSALIPPFKANEYHTLEQSSSVTFAYGTNTPQPFPLQDLA 473

  Fly   500 DKLRL-----QPGKSVSYFLAQDKLVEFADGLQMAATDTGRTSVRALLNTPDGEGPVLLSTESAT 559
            ::.|.     ..|.::...:.:|         ..|..|.|..::|.:....:   |:.::..:.:
 Frog   474 EQTRYTCVVKDDGTAIQANVFED---------ISAKPDQGSNAIRFVNGMQE---PINVTLNAVS 526

  Fly   560 -SQEPPLTLDKGNVPQLHRITPGFARVDI---NGK--KVASFEAKEGRLYSILVTGSARDG---Y 615
             .|..||.:....:.:|     |...:::   :||  ||.|.:...|..|:|::    ::|   .
 Frog   527 LGQLMPLQISNYTMQKL-----GIKEIEVFTASGKTWKVESIKFGFGSSYTIII----KEGNTEL 582

  Fly   616 QHNVIEVVALSTVSILWQLPQIVVMTAAEVMFSVTGLEFSYSQSPPSMKSVLQACWLLSVAIGNM 680
            |...:|.:..:|:.:..|:||..::||.||:||||||||||||:|.:|||||||.|||:||:||:
 Frog   583 QVEYVEDIQPNTIHMALQIPQYFLITAGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVGNI 647

  Fly   681 LVVVIAEFKFTSSQSGEFTLFASLMLVDMMIFLWLARSYQYKDQRE---DFEDDDDATIDSVMQS 742
            :|:::|.....|.|..|:.|||:|::...:||..:|..|.|.|..|   .|::::
 Frog   648 IVLIVAGASHISQQWAEYVLFAALLVAVCIIFAVMAYFYTYVDPAEIEAQFDEEE---------- 702

  Fly   743 KPKATTVDTTARKTNGIEAEPGYGAY 768
            |.|      .|::...:..:.|.|.|
 Frog   703 KKK------NAKEIEAMGVQNGDGPY 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yin	NP_001284844.1	2A1704	85..719	CDD:273343	253/671 (38%)
slc15a1	XP_012813171.2	2A1704	45..686	CDD:273343	253/671 (38%)