DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ec and AT1G52450

DIOPT Version :9

Sequence 1:	NP_001096877.1	Gene:	ec / 31339	FlyBaseID:	FBgn0000542	Length:	1765	Species:	Drosophila melanogaster
Sequence 2:	NP_175654.1	Gene:	AT1G52450 / 841676	AraportID:	AT1G52450	Length:	1136	Species:	Arabidopsis thaliana

Alignment Length:	936	Identity:	162/936 - (17%)
Similarity:	276/936 - (29%)	Gaps:	366/936 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   715 QLLEKSRLVEESHDLETALVLCNAAAGRARAAMDAPYSNPHTMTF--------------ARMKHN 765
            |:..|..|..|:.|:|...:|.:...          ||....::.              :.|.:.
plant    54 QVFLKLSLETENSDMEFTYLLGSVGC----------YSEDERLSSFCAKSLHMLANKLGSLMYYK 108

  Fly   766 TCVMRAR------------SLHRRI----------LVEKGAETE-AMPELKHMREGSTSSVKHVR 807
            .|:::|:            |:.|:|          .|.|.||:: |.||        |.....::
plant   109 KCLVKAKQALSVTFPDITDSVARQIRMNEKKKEMLSVIKDAESKIASPE--------TLVASTMK 165

  Fly   808 QNSKDRTLEKEQ---------------------------------QQLQFQQIQQIQQIHQIQQQ 839
            |.||.:.||.|:                                 :.|.|.:..:.:....:.::
plant   166 QVSKPKVLESEKIPDTREGVVKRLRSFWVRLDVKVKRDFMKVNIAKLLSFVETVRYRDGRDVLEK 230

  Fly   840 IPASIEIYATLPKRKSPL--------KALASASACDDNAIE-YEQEKQLATSPGKPERESR---- 891
            |.||        .||..:        |..:||..|.::..| :..:.|..|...|.:|..:
plant   231 ILAS--------ARKDMIWTFWMCCSKRFSSAEECKNHLEEVHAADFQPGTKKDKFQRIGKDWAR 287

  Fly   892 --------------------------SLFGRKDK---EKE-KRSRSEDRNKLTREFSLT------ 920
                                      ..|..|.|   .|| ..:..|:|.||.:|..|.
plant   288 KISIGSWEPVDAAAAVEMIKNQLADVKAFASKCKNGWSKEWPLAADEERGKLLKEIKLLLVSLCD 352

  Fly   921 -ETLLVNAKDTLK----KHKEDKDE--------------------------------KKEKDKSG 948
             :||..:.:|.:.    ||.|..:.                                ||.|.|..
plant   353 HKTLSCSVRDWVMHFPVKHLEKLEVSAQSLVYSRLVETPQSICFLECPELNQILDFLKKIKCKRN 417

  Fly   949 KKQHKIRRK----------------------LLMGGLIRRKNRSMPDLTEAVDDSTANA--GITH 989
            .....:||.                      ||:...:.:.|.:..|     |:.|.|.  .|.|
plant   418 DGAELVRRAVDSFLDRTRVKEKIDFDPQFSYLLLDRRLLKSNNAPCD-----DEGTINVFDPIAH 477

  Fly   990 HPHYPAQGVTTAGTLLGTSVDDSAVGLGKHGHGMSGYISEGHFDYSGSGSASNSGAGSNPNP--- 1051
            :....|||            ||....|               :||       ||.....|.|
plant   478 YAKAHAQG------------DDIIPWL---------------YDY-------NSVDKIFPKPIRE 508

  Fly  1052 ------------------NLERSKLMRKSFHGSGRQLTMVPKVAPPPPMRTSSTLTPQQQQQQQQ 1098
                              |:|.....:|.|.|....||::..:......|       ::..|:.|
plant   509 YNLDIWLAVLRAVQFTCRNMETKYTNQKLFLGYSATLTIIENICMSEDER-------RRNLQEDQ 566

  Fly  1099 QFHHEANLSNLSAMSSNTSISEDSCQTIITTCAQVHSEQSPLKDLQMLVAQD--ELPLPPPMELP 1161
            ...:             .||..|.|:.|:       .|.|..:.:.:...:|  |..|.|..::|
plant   567 WIRY-------------ASILCDRCEEIV-------PEISLARKIFVCAVRDVFEGALLPTFDVP 611

  Fly  1162 PYPSPPHSSCHSRQASEDFPPPPPPELDLEPLNQQLSQLQALEAASKQQRQQLE----------- 1215
            ......:.....:..|:|               :.|..:..|:.|...:...:|
plant   612 DLDDCLNLIREQKTRSDD---------------KVLESIGLLKLAVTYKVLLIESKILLIDNSRI 661

  Fly  1216 SLEGTTSILAQLQQRQHLLKLRK----------EQANHPGAATTDATWLKEL--QAKQANDLRAM 1268
            ||....:.|:....|.::|:|.|          |:.....|...|....:|.  |:|:.||  .:
plant   662 SLLNNLARLSVFDNRTYILQLMKPFLLSAIMNMERKAKADAVAADLALEEEKKPQSKKKND--KI 724

  Fly  1269 QRKLEASSPSSVRDLT--HR---------FEQTSIRSYASQELLSQPGQSQQLGQLRTQMNGLPN 1322
            .:...::|.||..|.|  |:         .|:.|:.  ....|.|:.|..:...:.:.|.....:
plant   725 NKHRASTSKSSPFDQTVEHKPPVNLELKTVEEDSME--PENALASENGPLESSSKTQNQEEATKD 787

  Fly  1323 GNAKM-DVDEVDAMPAVRNSLPAALSAHQLLPKPKYEMTQSQIAEEIREVELL------NT---- 1376
            |.|:| |:.:.|::.|...|.....:|       :|........:.:..:::|      ||
plant   788 GPAEMLDMPKEDSLSAHSESAIGGAAA-------RYNSALDMTLKALLNIKVLKEDLKNNTQRFQ 845

  Fly  1377 MVQQTLNQNGAAALPKRVKKKSVSFC 1402
            .|...|.....|.:.:.:|.:.|..|
plant   846 QVPSALQHFFNAFVSESIKTEGVYSC 871

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ec	NP_001096877.1	Peptidase_C19	183..410	CDD:239072
AT1G52450	NP_175654.1	DUF627	15..122	CDD:282615	12/77 (16%)
		DUF629	188..646	CDD:282614	87/546 (16%)
		UCH	808..1090	CDD:278850	11/71 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1887
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22975
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000