DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ec and AT5G02660

DIOPT Version :9

Sequence 1:	NP_001096877.1	Gene:	ec / 31339	FlyBaseID:	FBgn0000542	Length:	1765	Species:	Drosophila melanogaster
Sequence 2:	NP_195886.1	Gene:	AT5G02660 / 831187	AraportID:	AT5G02660	Length:	629	Species:	Arabidopsis thaliana

Alignment Length:	806	Identity:	139/806 - (17%)
Similarity:	260/806 - (32%)	Gaps:	287/806 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   318 DQVHAVLKAVGT---SLRLGDVFHQVSEPRWAQQTQHELVGIVSYYGKHYT------TFFF---- 369
            ::..:|.:.:|.   :|::.:.|...:|...:::..|....|:.|.||..|      ||..
plant     6 EKFSSVARGLGNYVDALKMINDFSSSAEREESEEFDHLEGEILEYLGKKSTNPALKFTFLLGSVS 70

  Fly   370 -HTKLKVWVYFDDANVKEVGPSWEGVVDKCSRGRYQPLLLLYAVPQQPTVGNGVGIGHVDV---- 429
             .:||:.:..:...::..:...::.||.......|....|.:..|....:...:.:..::.
plant    71 SFSKLERFPLYAAFSLLNLVREYKSVVYNKMASIYTQKALHFLKPIDRFLAERLTLETLEARIDK 135

  Fly   430 ----AMPASAPSIAGSVVRRAVTPSPEKPSLGNTRRAITPTPLRTPPNDYQNLSVIQKNIFPSNL 490
                .||..:|     ::|..:.|..|                     ||:.    ||:.:
plant   136 GPVPEMPVGSP-----LIRIRLVPDTE---------------------DYER----QKSYW---- 166

  Fly   491 AMGTD------------ETDAYISRKT-----VEHVLSAQYQNLSVIQDKIGGGNGVGVGQQSVD 538
             :|.|            |...|:..||     :|.||....:||..|
plant   167 -LGLDDEGSNFWKVPISEFKTYVEAKTGAVKDLEIVLKYVKKNLKWI------------------ 212

  Fly   539 KDGGFLSRKPIEAVLSAQLARRQ--HLQLQRSHSAESSSGHASSNGSSPPSDGLTMPEHLNQPRR 601
               .::.|     ..|.:.:.||  |..|::.|:.                 ||...:.::.| :
plant   213 ---AWICR-----TCSKKFSTRQACHDHLEQEHAT-----------------GLIPSQRMHMP-Q 251

  Fly   602 RDSGNWSGDRNSASSASSTTLDNPYLYMVAKRGVAAVPQSPTRHGLPYDPGYDSFSLSSTDSYPP 666
            |.|.:|:.                                               .:||...:.|
plant   252 RISEDWAD-----------------------------------------------KVSSVRDWKP 269

  Fly   667 KHALNPQLAKIPEAAMGVVPNGGAMPHGHGNGQLALSGDCEKLCHEADQLLEKSRLVEESHDLET 731
            ..|:         ||:.::.:..|    |....:...|.|.......||::.:|:|::|...|..
plant   270 VDAV---------AAVQMIKDQSA----HVKSFVYQDGWCNDWPLATDQVIARSQLLKEIRSLLV 321

  Fly   732 ALVLCNAAAGRARAAMDAPYSNPHTMTFARMK----------HNTCVMRARSLHRRILVEKGAET 786
            ..:.....:...|..:  .||....:..::.|          .:.|.:....|: ||||
plant   322 TFIQHKVLSDSFRERV--VYSLVLKLGISKQKLKDCRLLETPQSICFLECDELN-RILV------ 377

  Fly   787 EAMPELKHMREGSTS----SVKHVRQNSKDR------------TLEKEQQQLQFQQIQQIQQIHQ 835
             .:.::|..|:..|:    :|....|:|..|            .|:|   ||...:::......:
plant   378 -FLRKIKSKRDDGTNLVCQAVDGFLQSSLFRGKISVDLQFSFLLLDK---QLLLGELKHYDDEGK 438

  Fly   836 IQQQIPASIEIYATLPKRKSPLKALASASACDDNAIEYEQEKQLATSPGKPERESRSLFGRKDKE 900
            :|..:|:  :.|..:..|..     |..:...|| :...||:.....|..|:..:..::
plant   439 LQFLVPS--DYYGKVRSRGD-----AILTWLHDN-VNVSQEEDGFVFPKPPDANNYGIW------ 489

  Fly   901 KEKRSRSEDRNKLTREFSLTETLLVNAKDTLKKH-KED-----------KDEKKEKDKSGKKQHK 953
                      ..:.|...||.:||| ||...||. .||           :.:|||||::
plant   490 ----------LAVLRAIHLTVSLLV-AKIARKKQLVEDSNALHEAQILCQQKKKEKDET------ 537

  Fly   954 IRRKLLMGGLIRRKNRSMPD--------LTEAVDDSTANAGITHHPHYPAQGVTTAGTLLGTSVD 1010
               |.::..|:   ..:.|:        |::..||....|.|         |...:|.|...:..
plant   538 ---KQVLATLL---PETSPEFYVAHIDILSKLTDDDDILASI---------GNLFSGVLEEVAET 587

  Fly  1011 DSAVGL-GKHGHGMSGYISE-GHFDY 1034
            ||::.| .|....:.|.::: ..|||
plant   588 DSSILLIEKSRIALLGELNQLAFFDY 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ec	NP_001096877.1	Peptidase_C19	183..410	CDD:239072	19/105 (18%)
AT5G02660	NP_195886.1	DUF627	16..114	CDD:282615	18/97 (19%)
AT5G02660	NP_195886.1	DUF629	161..539	CDD:282614	92/537 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1887
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900