Protein Alignment ec and Usp53

DIOPT Version :9

• Sequence 1: NP_001096877.1
• Gene: ec / 31339
• FlyBaseID: FBgn0000542
• Length: 1765
• Species: Drosophila melanogaster
• Sequence 2: NP_001376197.1
• Gene: Usp53 / 295425
• RGDID: 1306615
• Length: 1082
• Species: Rattus norvegicus
• Alignment Length: 1255
• Identity: 306/1255 - (24%)
• Similarity: 469/1255 - (37%)
• Gaps: 366/1255 - (29%)

  Fly   125 GHINSAGNSERDRCINAVIE-LFQQLQTSSEPALCPEPLRRALASGPLAGRRFPLGCLGDAAECF 188
            |||     .:.|.||...:: :|.|.|.|.|.||..:.:|.|||......:||.||.:.||||||
  Rat    65 GHI-----CQGDACIFCALKTIFAQFQHSREKALPSDNIRHALAESFKDEQRFQLGLMDDAAECF 124

  Fly   189 ELLLHRVHSHISPD-DGDSCESSACIAHRRFAMRVIEQSVCK-CGANSEQLPFTQMVHYVSASAL 251
            |.:|.|:|.|::|: |.|.|.|.:|:.|::|||.:.||.||: |||:|:.||||:.|.|:|.:||
  Rat   125 ENILARIHFHLAPNRDADMCTSKSCVTHQKFAMTLYEQCVCRSCGASSDPLPFTEFVRYISTTAL 189

  Fly   252 TSQKSLALQSHQQLS---FGQLLRAAGNMGDIRDCPNTCGAKIGICRALLNRPEVVSIGIVWDSE 313
            .::....::.|::..   |..||:||....|.|.||:.||.||.|.|.|:|.||:|:||:|||||
  Rat   190 CNEVERMMERHERFKPEMFADLLQAANTADDYRKCPSNCGQKIKIRRVLMNCPEIVTIGLVWDSE 254

  Fly   314 RPAADQVHAVLKAVGTSLRLGDVFHQVSEPRWAQQTQHELVGIVSYYGKHYTTFFFHTKLKVWVY 378
            .  :|....|::::.|.|.|..:|::|::.. |..::..|||::.|..:||..|.||||...||:
  Rat   255 H--SDLTEDVVRSLATHLYLPGLFYRVTDEN-AVDSELHLVGMICYTSRHYCAFAFHTKSSKWVF 316

  Fly   379 FDDANVKEVGPSWEGVVDKCSRGRYQPLLLLYAVPQQPTVGNG------VGIGH---VDVAMPAS 434
            ||||.|||:|..|:.||.||.|...|||||.||.|....|...      |...|   |:..|...
  Rat   317 FDDALVKEIGTRWKDVVSKCIRCHLQPLLLFYANPDGTAVSTEDALKQVVHWSHYKSVEENMGCE 381

  Fly   435 APSI----------AGSVVRRAVTPSPEKPSLGNTRRAITPTPLRTPPNDYQNLSVIQKNIFPSN 489
            .|.|          .|..:::......:..::.:..|:...|..|..|
  Rat   382 KPIIYKPDNLKENGFGGQIKQKENHKFQGDNISSFNRSQVQTSGRRAP----------------- 429

  Fly   490 LAMGTDETDAY--ISR----KTVE--HVLSAQYQNLSVIQDKIGGGNGVGVGQQSVDKD-GGFLS 545
            :.:..|:.:..  |||    |.:|  :.||:|.:.|...|.|     ..|..:..||:| ..|.|
  Rat   430 VKLSHDQREKIKDISRECALKAMEQKNALSSQRKELEKGQRK-----DTGRHRDVVDEDLSSFKS 489

  Fly   546 RKPIEAVLSAQLARRQ----HL---------QLQRSHSAESSSGHASSNGSSPPSDGLTMPEHLN 597
            ..|     .|....||    ||         :..|:.|..||||...|  ||...:.|...|...
  Rat   490 ASP-----PASDGFRQQGNPHLYHSQGKGPCKHDRAASESSSSGKVMS--SSRSQNPLVPGEKTT 547

  Fly   598 QPRRRDSG------NWSGDRNSASSASSTTLDNPYLYMVAKRGVAAVPQSPTRHGLPYDPGYDSF 656
            ...:.|||      :....|:...|..|.|...       .||     ..|.|..|..|   ..|
  Rat   548 GKAKSDSGTGYDTDSSQDSRDKGGSYGSRTKSR-------HRG-----WKPMRETLNVD---SVF 597

  Fly   657 SLSSTDSYPPKH--------------------ALNPQ---LAKIPEAAMGVVPNGGAMPHGHGNG 698
            |.|....:.|:.                    ..||:   |..|.|..|.......:....:|.|
  Rat   598 SESEKRQHSPRRKSDIGNRPKCSKDQSCNNWPKANPKRKGLMTIYEDEMKQEAGSRSSHETNGKG 662

  Fly   699 QLALSGDCEKLCHEADQLLEKSRLVEESHDLETALVLCNAAAGRARAAMDAPYSNPHTMTFARMK 763
            ....:|..|.....:...::::....||.|          ......|::|:|          .:.
  Rat   663 AEKNTGAAESRGPGSSWQMQRTESGYESSD----------HVSNGSASLDSP----------GID 707

  Fly   764 HNTCVMRARSLHRRILVEKGAETEAMPELKHMREGSTSSVKHVRQNSKD--RTLEKEQQQLQFQQ 826
            .:..||           :.|. .:|..|...|...:|.||:.|...|||  ....|:.|.|:
  Rat   708 GSGAVM-----------DVGG-GKAFSEQIKMNSPNTDSVECVSHQSKDLPEGFRKDLQDLE--- 757

  Fly   827 IQQIQQIHQIQQQIPASIEIYATLPKRKSPLKALASASACDDNAIEYEQEKQLATSPGKPERESR 891
                                                   .||.:.|...|..:..   |.....|
  Rat   758 ---------------------------------------ADDKSYELHPESHVQI---KNHLIKR 780

  Fly   892 SLFGRKDKEKEKRSRSEDRNKLTREFSLTETLLVNAKDTLKKHKEDKDEKKEKDKSGKKQHKIRR 956
            |..|            |..:||....| ::|   .|::.:.:..|.|.||.::.|..:.::
  Rat   781 SQIG------------ETNDKLFPSAS-SQT---PAREYVYQTNEQKGEKPDRTKCSEWRN---- 825

  Fly   957 KLLMGGLIRRKNRSMPDLTEAVDDSTANAGITHHPHYPAQGVTTAGTLLGTSVDDSAVGLGKHGH 1021
                           .:::|.:       |:..|                  ||:|:|
  Rat   826 ---------------TEISEGM-------GLPFH------------------VDESSV------- 843

  Fly  1022 GMSGYISEGHFDYSGSGSASNSGAGSNPNPNLERSKLMRKSFHGSGRQLTMVPKVAPPPPMRTSS 1086
                           :|...||....:|:.       :..|...:|.:....|.:..|
  Rat   844 ---------------AGKRVNSNETVSPSS-------LSSSVRTAGLKAETGPVIFWP------- 879

  Fly  1087 TLTPQQQQQQQQQFHHEANLSNLSAMSSNTSISEDSCQTIITTCAQVHSEQSPLKDLQMLVAQDE 1151
                  ||...:|.:.|.:||.  .::..::.:.||||     ..::|..:||
  Rat   880 ------QQNITEQGYSENSLSR--ELTRQSACNADSCQ-----MPKLHCHRSP------------ 919

  Fly  1152 LPLPPPMELPPYPSPPHSSCH-SRQASEDFPPPPPPELDL-EPLNQQLSQL--QALEAASKQQRQ 1212
                     ||.|...:|:.. .|.....|    .|::.| |..|...|.|  .:|..||.
  Rat   920 ---------PPLPPKKYSTTSVPRLERAGF----IPDVRLPEAFNTNFSSLPKHSLSTASG---- 967

  Fly  1213 QLESLEGTTSILAQLQQRQHLLKLRKEQANH-PGAATT-----DATWLKELQAKQANDLRAMQRK 1271
              .|.|| ::.:.| ::.:..::::.:.||. |.:.:|     ::..|..:..:...|.|:|
  Rat   968 --PSSEG-SAYMTQ-EKDKETIQVKHQAANSCPSSCSTGGFQANSKALVNMFCEPDQDSRSM--- 1025

  Fly  1272 LEASSPSSVRDLTHRFEQTS 1291
                .||....||..|...|
  Rat  1026 ----CPSETVSLTTYFSVDS 1041

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ec	NP_001096877.1	Peptidase_C19	183..410	CDD:239072	106/231 (46%)
Usp53	NP_001376197.1	UCH	30..348	CDD:395355	127/290 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002086
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000