Protein Alignment ec and usp53b

DIOPT Version :9

• Sequence 1: NP_001096877.1
• Gene: ec / 31339
• FlyBaseID: FBgn0000542
• Length: 1765
• Species: Drosophila melanogaster
• Sequence 2: XP_005171014.1
• Gene: usp53b / 100537347
• ZFINID: ZDB-GENE-090312-168
• Length: 1029
• Species: Danio rerio
• Alignment Length: 1238
• Identity: 293/1238 - (23%)
• Similarity: 454/1238 - (36%)
• Gaps: 400/1238 - (32%)

  Fly   136 DRCINAVIE-LFQQLQTSSEPALCPEPLRRALASGPLAGRRFPLGCLGDAAECFELLLHRVHSHI 199
            |.||...:: :|.|.|.|.|.||..:.||.|||......:||.||.:.|||||||.:|.|:|.|:
Zfish    82 DACIFCALKSIFCQFQQSRERALPSDTLRHALAETFKDEQRFQLGLMDDAAECFENILERIHLHL 146

  Fly   200 SPDDG-DSCESSACIAHRRFAMRVIEQSVCK-CGANSEQLPFTQMVHYVSASALTSQKSLALQSH 262
            ..|.. ::|.|.:||.|::|||.:.||.||: |||:|:.||||::|||||::||..|....|:..
Zfish   147 VSDSATETCTSKSCITHQKFAMTLYEQFVCRSCGASSDPLPFTELVHYVSSTALCQQVERILEKT 211

  Fly   263 QQL---SFGQLLRAAGNMGDIRDCPNTCGAKIGICRALLNRPEVVSIGIVWDSERPAADQVHAVL 324
            .:|   .||:||:||..:||:|:||:.||..|.|.|.|:|.||:|:||.|||:|:  :|....|:
Zfish   212 DRLRSDMFGELLQAANTIGDLRNCPSNCGQSIKIRRVLMNCPEIVTIGFVWDAEQ--SDLTEDVI 274

  Fly   325 KAVGTSLRLGDVFHQVSEPRWAQQTQHELVGIVSYYGKHYTTFFFHTKLKVWVYFDDANVKEVGP 389
            :.:|.:|.|..:|::|::....::..| |||::.|..:||..|.||:|...|::||||.|||:|.
Zfish   275 RCLGPNLNLSGLFYRVTDENAKKRDLH-LVGMICYSSRHYLAFAFHSKSSKWIFFDDATVKEIGS 338

  Fly   390 SWEGVVDKCSRGRYQPLLLLYAVPQQPTVGNGVGIGHVDVAMPASAPSIAGSVVRRAVTPSPEKP 454
            .|:.|..||.||.:|||||.||.|      :|..:.:.|                     :|.:.
Zfish   339 KWKDVASKCIRGHFQPLLLFYANP------DGTAVSNED---------------------APRQT 376

  Fly   455 SLGNTRRAITPTPLRTPPNDYQNLSVIQKNIFPSNLAMGTDETDAYISRKTVEHVLSAQYQNLSV 519
            ::.:...    :||.....|.| ||..:|                                 |..
Zfish   377 TMWSRYN----SPLNGKGTDTQ-LSGCKK---------------------------------LDS 403

  Fly   520 IQDKIGGGNGVGVGQQSVDKDGGFLSRKPIEAVLSAQLARRQHLQLQRSHSAESSS--GHASSNG 582
            ::|...|......|..          :.|:::..|    |.:.|....|...|||.  .|....|
Zfish   404 VRDASAGSQRTNQGSH----------KTPMQSSTS----RLKVLPESPSRFRESSRDLSHRGGGG 454

  Fly   583 SSPPSDGLTMPEHLNQPRRRDSGNWSGDRNSASSASSTTLDNPYLYMVAKRGVAAVPQSPTRHGL 647
                             :||:|     ||
Zfish   455 -----------------QRRES-----DR------------------------------------ 461

  Fly   648 PYDPGYDSFSLSSTDSYPPKHALNPQLAKIPEAAMGVVPNGGAMPHGHGNGQLALSGDCEKLCHE 712
                     |...:||:..|....|:|:..||       ||   |..|          ||:
Zfish   462 ---------SYRRSDSFQHKDMTYPRLSSPPE-------NG---PRFH----------CEQ---- 493

  Fly   713 ADQLLEKSRLVEESHDLETALVLCNAAAGRARAAMDAPYSNPHTM--TFARMKHNTCVMRARSLH 775
                                                    .|.|:  ..:|.:|:       |:|
Zfish   494 ----------------------------------------RPRTLPSRVSRTEHS-------SVH 511

  Fly   776 RRILVEKGAETEAMPELKHMREGSTSSVKHVRQNSKDRTLEKEQQQLQFQQIQQIQQIHQIQQQI 840
            .|:..::....:.|.. ...|...:||:.|  :.|.:.| |:.:.:..::.::::..:..:..:
Zfish   512 PRVSPQESRSNQGMAS-GVSRHADSSSLSH--RGSTNPT-ERGKSKPSWRPVREVLNVDSVLSE- 571

  Fly   841 PASIEIYATLPKRKSPLKALASASACDDNAIEYEQEKQLATSPGKPERESRSLFGR---KDKEKE 902
                                          :|..|::|.....|.|....|....|   |||:|.
Zfish   572 ------------------------------LERRQQQQQQQQRGSPRCVRRFAHERGLMKDKQKG 606

  Fly   903 KRSRSEDRNKLTREFSLTETLLVNAKDTLKKHKEDKDEKKEKDKSGKKQHKIRRKLLMGGLIRRK 967
            ..:..||.::|..|                         .:..:..::|..:.|......:.:|.
Zfish   607 LMTIYEDDSRLETE-------------------------SQSSQESQRQMMVTRSKGGANVAQRS 646

  Fly   968 NRSMPDLTEAVDDST--ANAGITHHPHYP---------------AQGVTTAGTLLGTSVDDSAVG 1015
            :..:...||:..:|:  .::|.| :|..|               ||.:...|   ..:.|||.:.
Zfish   647 DNWVIQRTESGYESSDRLSSGST-NPDSPGVENFTGKELRLSQDAQHLRDQG---HNNQDDSKME 707

  Fly  1016 L-------GKHGHGMSGYISEGHFDYSGSGSASN----SGAGSNPNPNLERSKLMRKSFHGSGRQ 1069
            .       |||...:.|..|| |. ..||.|:..    |..|:....|.|:..        ||..
Zfish   708 AARSPLYHGKHLAKIQGKNSE-HL-MKGSPSSRRKLRYSSCGTRKAGNTEKDP--------SGVD 762

  Fly  1070 LTMVPKVAPPPPMRTSSTLTPQQQQQQQQQFHHEAN---LSNLSAMSSNTSISEDSCQTIITTCA 1131
            |                   |.:||:...|:||...   |..|..:||:...|.|.....::
Zfish   763 L-------------------PPEQQELSMQWHHSPESPLLRRLGKISSSECNSSDELTNPLS--- 805

  Fly  1132 QVHSEQSPLKDLQMLVAQDELPLPP----PMELPPYPSPPHSSCHSRQAS---EDFPPPPPPELD 1189
              ..|.|..:.....||..|.|.|.    |.|.....|.|..:.||:.|.   |...||..|.:.
Zfish   806 --EQEDSAYRSSTSEVAPHESPGPNRSSYPWEESAIQSGPSIASHSKHAQRPIEIKTPPFRPRIL 868

  Fly  1190 LEPLNQQLSQLQALEAASKQQ----RQQLESLEGTTSILAQLQQRQHLLKLRKEQAN-------- 1242
            .|| :|..|:.....|.|...    .:::| :.||....:.:..:....:.|.||.:
Zfish   869 QEP-SQTASRASGRGAPSSSHSGAVHRRME-INGTCPSSSDVSSKSGSDQERGEQVSSEPEGWDK 931

  Fly  1243 -----HPGAATTDATWLKELQAKQANDLRAM---QRKLEASSP------SSVRDLTH--RFEQTS 1291
                 .||:.....|:. .:.....:..|..   ||.|..|.|      ...||..|  |.|..|
Zfish   932 PSSSVSPGSGVALTTYF-SVDNCMTDTYRLKYHHQRPLVLSMPEPRGAGKDGRDAGHSSRMENQS 995

  Fly  1292 IRS 1294
            .|:
Zfish   996 ERA 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ec	NP_001096877.1	Peptidase_C19	183..410	CDD:239072	107/231 (46%)
usp53b	XP_005171014.1	Peptidase_C19	41..>186	CDD:271592	47/103 (46%)
		UCH	42..359	CDD:278850	126/279 (45%)
		Peptidase_C19	130..359	CDD:239072	107/231 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	276	1.000	Domainoid score	I1707
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002086
OrthoInspector	1	1.000	-	-		otm25235
orthoMCL	1	0.900	-	-		OOG6_104646
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5015
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.840