DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2901 and GDE1

DIOPT Version :9

Sequence 1:	NP_570077.1	Gene:	CG2901 / 31338	FlyBaseID:	FBgn0029679	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_015215.1	Gene:	GDE1 / 855994	SGDID:	S000006031	Length:	1223	Species:	Saccharomyces cerevisiae

Alignment Length:	208	Identity:	47/208 - (22%)
Similarity:	79/208 - (37%)	Gaps:	53/208 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTYESHLTIEWRQQYMRYGDLKELIKQGVE-----------------NAPSPLTSSDYEVQ 48
            ||||||:.:|...||..||:.|..||::||:...                 ..|:.:..|....|
Yeast     1 MKFGKTFANHRIPEWSSQYVGYKSLKKMIKEITRLQEDIYRAHNKNSYDEGRPPTKMRDSSNSAQ 65

  Fly    49 AY-----YKAFEETFLTECQSELTGVNNFF----------LEKLLEARRKHGHLKLQLLAYSREP 98
            .|     .:....:|......::..|:.|:          .|:||.: .:...:|..|:..:.:.
Yeast    66 NYLDSPKIQKLLASFFFAVDRDIEKVDTFYNSQYAEYKKRFERLLSS-NQFNEIKSTLVVDANKE 129

  Fly    99 GHTGSDSSLSQRAERSQKKLM--TTRQLRYAYAEFYLSLVLIQN--------------YQSLNET 147
            ....  .:|..:..|....|:  |::..|.:|.:.  .|:.||:              |..||:.
Yeast   130 DAVA--QTLLTKDTREMNMLLKGTSQASRLSYHKD--DLIEIQSILAELRKQFRNLKWYAELNKR 190

  Fly   148 GFRKICKKYDKNM 160
            .|.||.||.||.:
Yeast   191 AFGKILKKLDKKV 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	COG5408	1..162	CDD:227695	47/208 (23%)
		SPX_XPR1_like	2..158	CDD:269898	44/203 (22%)
		EXS	260..597	CDD:281164
GDE1	NP_015215.1	COG5408	1..300	CDD:227695	47/208 (23%)
		ANKYR	361..594	CDD:223738
		ANK repeat	427..466	CDD:293786
		ANK repeat	468..501	CDD:293786
		ANK repeat	506..535	CDD:293786
		Ank_2	508..603	CDD:403870
		ANK repeat	540..569	CDD:293786
		ANK repeat	572..603	CDD:293786
		GDPD_YPL110cp_fungi	871..1219	CDD:176548
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810