Protein Alignment CG2901 and SYG1

DIOPT Version :10

• Sequence 1: NP_570077.1
• Gene: CG2901 / 31338
• FlyBaseID: FBgn0029679
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_012217.3
• Gene: SYG1 / 854764
• SGDID: S000001309
• Length: 902
• Species: Saccharomyces cerevisiae
• Alignment Length: 872
• Identity: 198/872 - (22%)
• Similarity: 309/872 - (35%)
• Gaps: 295/872 - (33%)

  Fly     1 MKFGKTYESHLT----IEWRQQYMRYGDLKELIKQGVENAPS-PLTSSDY-----EVQAY----- 50
            |||.    .|||    .|||.:|:.|...|:.:::..|...: ...||.|     .|..|
Yeast     1 MKFA----DHLTESAIPEWRDKYIDYKVGKKKLRRYKEKLDAEEEQSSSYRSWMPSVSVYQTAFQ 61

  Fly    51 ----------------------YKAFEETFLTE------CQSELTGVNNFFLEKLLEARRKHGHL 87
                                  |.|.:..|:.:      ...:|:..|.|:|..|.|..:|...|
Yeast    62 QREPGKSRSDGDYRSGPAFKKDYSALQREFVADFIEDWLISFQLSKCNEFYLWLLKECDKKFEVL 126

  Fly    88 KLQLLAYSREPGH---------------------------------TGSDS-------------- 105
            :.||..||.:..:                                 ..|||
Yeast   127 QSQLHYYSLQKNYERDNLNRSSSNVDMSTSLYAAGLAGRSDSRVNSIDSDSRSVMYGSMPCTKEA 191

  Fly   106 -----------------------------SLSQ--RAERSQK------------KLMTTRQLR-- 125
                                         ||.|  |.:.|.:            :.|||.|.|
Yeast   192 KKPRLSLLAYCQKVLKDNRLLPSWPKRGFSLLQDLRQDASSRGRETFAFGASFLETMTTTQARNL 256

  Fly   126 --YAYAEFYLSLVLIQNYQSLNETGFRKICKKYDK--------------------------NMRS 162
              .|..|:||.|.|:::::.:|.|||||:.||:||                          |::.
Yeast   257 LSNAIIEYYLYLQLVKSFRDINVTGFRKMVKKFDKTCHTRELTTFMSYARTHYTLFKHADANVQL 321

  Fly   163 VAAGRWFVENVLDAPFTDVRLLQR-------MTIEVEDLYTTHLANG--DRSLAMEKLRVPPLGE 218
            ||.....:.:....|.:::...||       :..::.:.:||.|.|.  ||.....||:...:..
Yeast   322 VAQKMQQITSSQPTPTSELSSAQRDKEPITWLETQITEWFTTALTNSPKDRKHNTHKLKKLTIQY 386

  Fly   219 PTPPSMVFR----------AGIALGMLIMLLVAT--------AISYWKRAPLEDHTPGLMRLFRG 265
            .....||.|          .|:.:|:.:.|:..|        ..|:..:.        |..|:.|
Yeast   387 SISEQMVHRNNRSIVQMLVVGLGIGVSMTLITYTLYLGISSEETSFTHKI--------LFPLWGG 443

  Fly   266 PFTWVIFNFYMAANVAGWQQAGVNH--ILIFEIDPRSHLQ-----------P-----ATFLEIAC 312
            .:..::..|....|...|.:.|:|:  |::.||..::..|           |     .||..:.|
Yeast   444 WYMVLLIAFLFLVNCFIWHRTGINYRFIMLGEIQSKNGTQFFNNDFATSKIPLKLYFLTFFIVPC 508

  Fly   313 ------TFGILWALSMLGFLYNDLIG-VSDPYVFPLGLILIMVGLLVVPLPIMNWP----ARWWT 366
                  :|. |..|:.|||||   || ||..::.|.|||           |.  |.    .|.|.
Yeast   509 AVCSMLSFA-LEKLTPLGFLY---IGIVSFLFLCPSGLI-----------PY--WDKVVHTRKWL 556

  Fly   367 IKLVGRVITAPLHYVGFADFWMGDQMNSLVSCIVDHYYTVRFYAISWLRYDRVNN--C-FEPDVM 428
            :..:.|::.:....|.|.||::||.:.||...|.|   ...|:.:    |....|  | ......
Yeast   557 VVTLIRLMMSGFFPVEFGDFFLGDIICSLTYSIAD---IAMFFCV----YSHTPNNLCGSSHSRA 614

  Fly   429 VPITMCLPGWFRFAQCLRRFRDSGSKSMSYLINAGKYSTTFLVVLFSTLRRNSEGGYANTFSNPY 493
            :.:..|||.::||.||||||.|||. ...:|:||.||  |..:...:||........:.....|
Yeast   615 MGVLSCLPSYWRFMQCLRRFADSGD-WFPHLLNAAKY--TLGIAYNATLCAYRLSDRSEQRRTP- 675

  Fly   494 TWLFLSSCVVATIYCYLWDVIRDFGLFR-------IMR-------------GERIFLRKQLVYPQ 538
               |:....:.:|....||::.|:....       ::|             |...|.||.:
Yeast   676 ---FIVCATLNSILTSAWDLVMDWSFAHNTTSYNWLLRDDLYLAGKKNWENGSYSFSRKLV---- 733

  Fly   539 AFYYFVIVENLVLRLFWAVEFTILYHNLMTPYNMRTISSILEITRRFIWNYVRLENEHLFNCGNF 603
              |||.::.::::|..|.| :.|....:........|.::||:.|||:|...|:||||:.|...|
Yeast   734 --YYFAMIWDILIRFEWIV-YAIAPQTIQQSAVTSFILALLEVLRRFVWIIFRVENEHVANVHLF 795

  Fly   604 RATRDIHLAALNPRQERMLESMMDESD 630
            |.|.|   |.|.....::.:..||.||
Yeast   796 RVTGD---APLPYPIAQVGDDSMDSSD 819

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	SPX_XPR1_like	2..158	CDD:269898	59/292 (20%)
		EXS	259..597	CDD:460816	102/389 (26%)
SYG1	NP_012217.3	COG5408	1..310	CDD:227695	62/312 (20%)
		COG5409	402..803	CDD:227696	114/449 (25%)