DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2901 and VTC4

DIOPT Version :9

Sequence 1:	NP_570077.1	Gene:	CG2901 / 31338	FlyBaseID:	FBgn0029679	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_012522.2	Gene:	VTC4 / 853441	SGDID:	S000003549	Length:	721	Species:	Saccharomyces cerevisiae

Alignment Length:	226	Identity:	47/226 - (20%)
Similarity:	76/226 - (33%)	Gaps:	72/226 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTYESHLTIEWRQQYMRYGDLKELIKQGVENAPSPLTSSDYEVQAYYKAFEETFLTECQSE 65
            ||||:.....|..::...|:.|.|||..::..:.......|          :..|..||...:.|
Yeast     1 MKFGEHLSKSLIRQYSYYYISYDDLKTELEDNLSKNNGQWT----------QELETDFLESLEIE 55

  Fly    66 LTGVNNFFLEKLLEARRKHGHLKLQLLAYSREPGHTGSDSSLSQRAERSQKKLMTT--------- 121
            |..|..|       .:.||                    |.:.:|.:..|:::..|
Yeast    56 LDKVYTF-------CKVKH--------------------SEVFRRVKEVQEQVQHTVRLLDSNNP 93

  Fly   122 -RQLRYAYAEFYLSLVL-----IQNYQSLNETGFRKICKKYDKNMRSVAAGRWFVENVLDAPFTD 180
             .||.:...|..||.::     :..:..||.|||:||.||:||....:.           .|...
Yeast    94 PTQLDFEILEEELSDIIADVHDLAKFSRLNYTGFQKIIKKHDKKTGFIL-----------KPVFQ 147

  Fly   181 VRL---------LQRMTIEVEDLYTTHLANG 202
            |||         ...:.:::..||.....:|
Yeast   148 VRLDSKPFFKENYDELVVKISQLYDIARTSG 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	COG5408	1..162	CDD:227695	40/175 (23%)
		SPX_XPR1_like	2..158	CDD:269898	37/170 (22%)
		EXS	260..597	CDD:281164
VTC4	NP_012522.2	COG5036	1..497	CDD:227369	47/226 (21%)
VTC4	NP_012522.2	DUF202	593..721	CDD:415817
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343551
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.569298	Normalized mean entropy	S1995
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.790