DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2901 and PHO1;H1

DIOPT Version :9

Sequence 1:	NP_570077.1	Gene:	CG2901 / 31338	FlyBaseID:	FBgn0029679	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_564940.1	Gene:	PHO1;H1 / 843205	AraportID:	AT1G68740	Length:	784	Species:	Arabidopsis thaliana

Alignment Length:	837	Identity:	199/837 - (23%)
Similarity:	316/837 - (37%)	Gaps:	261/837 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTYESHLTIEWRQQYMRYGDLKELIKQ------GVEN------------------------ 35
            :||.|.:|..|..||:..::.|..||:.:|:      |||.
plant     2 VKFTKQFEGQLVPEWKDAFVDYSQLKKDLKKIHLFTNGVEKKHTETSLIKTVKSSLGRLSIFGNK 66

  Fly    36 --------------APSPLTSSDYEVQAYYKAFEET-----FLTECQSELTGVNNF-------FL 74
                          |.|...:..||.:...|..::|     |......:|..||.|       ||
plant    67 GREQSRVIQVHKKLASSGSNNDVYETELLEKIADDTDAAKEFFACLDMQLNKVNQFYKTKEKEFL 131

  Fly    75 EK----------LLE----------------------------------ARRKHGHLKLQLLAY- 94
            |:          |:|                                  .|.:...::||:...
plant   132 ERGECLKKQMDILIELKDAFKQKQANGESTQESKEDDSISCTISCEYDSVRGRTEEMQLQVSCLD 196

  Fly    95 --------------SREP-GHTGSDSSLSQRAER------------------------------- 113
                          |.|| .....||.|:..:.|
plant   197 NLEDNGEEALESLGSEEPIKANNEDSKLTTVSSRVFSCQGKNVKIKIPLTNPSRTFSAISYLINQ 261

  Fly   114 ----------------SQKKLM-TTRQLRYAYAEFYLSLVLIQNYQSLNETGFRKICKKYDKNMR 161
                            |:|||. ..:.::.|..|.:..|..::.|::||...|..|.||:||
plant   262 SSSKKNGPDGGNKLQISKKKLSHAEKMIKGALTELFKGLNYLKTYRNLNILAFMNILKKFDK--- 323

  Fly   162 SVAAGRWFVE---NVLDAPFTDVR-LLQRMTIEVEDLYTTHLANGDRSLAMEKLRVPPLGEPTPP 222
              ..|:..:.   .|:::.:.::. .:..::.|||:.:..|||..:|..||:.|:  |.......
plant   324 --VTGKQILPIYLKVVESSYFNISDKVMILSDEVEEWFIKHLAGENRRKAMKYLK--PHHRKESH 384

  Fly   223 SMVFRAGIALGMLIMLLVATAISYWKRAPLEDHTPGLMRLFRGPFTWVIFNFYM----------- 276
            |:.|..|:..|..:.||....|        ..|..|:.|.....      .|||
plant   385 SVTFFIGLFTGCFVALLAGYII--------VAHLTGMYRQHSAN------TFYMETAYPVLSMFG 435

  Fly   277 ---------AANVAGWQQAGVNHILIFEIDPRSHLQPATFLEIACT------FGILWA-LSML-- 323
                     ..|:..|::|.:|:..|||:..::.|:..... :.||      .|:::. ||:|
plant   436 LLFLHLFLYGCNIFMWRKARINYSFIFELGSKNELKYRDVF-LICTASMSAIAGVMFVHLSLLEK 499

  Fly   324 GFLYNDLIGVSDPYVFPLGLILIMVGLLVVPLPIMNWPARWWTIKLVGRVITAPLHYVGFADFWM 388
            |:.:..:..:  |.:..||.:||    |:.||.|....:|:..|.::..::.:||:.|...||:|
plant   500 GYSFRQVQVI--PGLLLLGFLLI----LICPLNIFYKSSRYRLISVIRNIVFSPLYKVVMLDFFM 558

  Fly   389 GDQMNSLVSCI-----VDHYYTVRFYAISWLRY-DRVNNCFEPDVMVPITMCLPGWFRFAQCLRR 447
            .||:.|.|..:     :..||....||.....| .||.  :..|:...::. ||.::|..||.||
plant   559 ADQLCSQVPMLRNLEYIACYYITGSYATQDYEYCMRVK--YYRDLAYAVSF-LPYYWRAMQCARR 620

  Fly   448 FRDSGSKSMSYLINAGKYSTTFLVVLFSTLRRNSEGGYANTFSNPYTWLFLSSCVVATIYCYLWD 512
            :.|.|  ..|:|:|.|||.:..|..       .::..|....|..:..|.::...|||||...||
plant   621 WFDEG--ETSHLVNLGKYVSAMLAA-------GTKVAYEKERSLGWLCLVVAMSSVATIYQLYWD 676

  Fly   513 VIRDFGLFRIMRGERIFLRKQLVYPQ-AFYYFVIVENLVLRLFWAVEFTILYHNLMTPYNMRTIS 576
            .::|:||.: ......:||.||:..| :.|||.:|.||||||.|..  |:| |:.....:.|...
plant   677 FVKDWGLLQ-HNSNNPWLRNQLMLRQKSIYYFSMVLNLVLRLAWLQ--TVL-HSSFEHVDYRVTG 737

  Fly   577 ---SILEITRRFIWNYVRLENEHLFNCGNFRATRDIHLAALNPRQERMLESMMDESD 630
               :.||:.||..||:.|||||||.|.|.|||.:.:.|    |.:|      :||.|
plant   738 LFLAALEVIRRGQWNFYRLENEHLNNAGKFRAVKTVPL----PFRE------VDEED 784

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	COG5408	1..162	CDD:227695	56/324 (17%)
		SPX_XPR1_like	2..158	CDD:269898	54/319 (17%)
		EXS	260..597	CDD:281164	108/375 (29%)
PHO1;H1	NP_564940.1	SPX_PHO1_like	3..331	CDD:269897	57/332 (17%)
		SPX	4..336	CDD:281146	56/336 (17%)
		EXS	444..761	CDD:281164	104/339 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940