DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2901 and SHB1

DIOPT Version :9

Sequence 1:	NP_570077.1	Gene:	CG2901 / 31338	FlyBaseID:	FBgn0029679	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_194265.2	Gene:	SHB1 / 828638	AraportID:	AT4G25350	Length:	745	Species:	Arabidopsis thaliana

Alignment Length:	762	Identity:	201/762 - (26%)
Similarity:	320/762 - (41%)	Gaps:	181/762 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTYESHLTIEWRQQYMRYGDLKELIK--QGVEN---------APS------------PLTS 42
            |:|||.:.|.:..||::.|:.|..||.:::  |...|         .||            .|.|
plant     1 MRFGKEFVSQMIPEWQEAYIDYAYLKTILQDIQASRNRSDSNNQSSTPSFARNLTRRYNRDALVS 65

  Fly    43 SDYEV------------------QAYYKA------FEETFLTECQSELTGVNNFFLEKLLEARRK 83
            .::::                  ..:.||      ||.||......|...||||:..|:..||.:
plant    66 ENHDIVVNTVTRLEEGLETAAYETTFLKAGEAGGDFEVTFFRTLDREFNKVNNFYRLKVETARTE 130

  Fly    84 HGHLKLQ---LLAY--------SREP--------------GHTGSDSSLSQR------------- 110
            ...|..|   |:|:        .:.|              ...||.|..::.
plant   131 ALALNKQMDALIAFRHKVMDQNQKNPSVFDSVSEDINGSASEVGSSSKCTEHNVALADLMRNEDT 195

  Fly   111 -----AER----------------------SQKKLMTTR--------QLRYAYAEFYLSLVLIQN 140
                 .||                      .|.:|..||        :|:.|:.|||..|..::|
plant   196 SNESILERIRMNKTREITPLSAIKTILKVHKQDELKFTRDNLKEVEKRLQVAFIEFYQKLRHLKN 260

  Fly   141 YQSLNETGFRKICKKYDKNMRSVAAGRWFVENVLDAPFTDVRLLQRMTIEVEDLYTTHLANGDRS 205
            |..||.:...||.|||||..:..|| :.::|.|..:..:....:.::.::||.::..|.:|.:|.
plant   261 YSFLNASAVSKIMKKYDKIAKRNAA-KLYMEMVDKSFLSSSEEVHKLLLKVESIFIEHFSNSNRR 324

  Fly   206 LAMEKLRVPPLGEPTPPSMVFRAGIALGMLIMLLVATAISYWKRAPLEDHTPG-------LMRLF 263
            ..|..|| |.:.:.. ..:.|..|...|..|.|:||..:....|..:  .|||       :..|:
plant   325 EGMSHLR-PKINKER-HLITFSTGFFFGCGISLIVALGLIIHARNIM--GTPGQRTYMETMFPLY 385

  Fly   264 RGPFTWVIFNF-YMAANVAGWQQAGVNHILIFEIDPRSHLQPATFLEIACTFGILWALSMLGFLY 327
            |. |.:|:.:. ..|||:..|::..||:..||.....:.|.....|.:  :|| |..||:...|.
plant   386 RF-FGFVVLHMDVYAANIYFWRRYRVNYSFIFGFKQGTELGYRHVLLL--SFG-LGTLSLCAVLL 446

  Fly   328 N---DLIGVSDPY-----VFPLGLILIMVGLLVVPLPIMNWPARWWTIKLVGRVITAPLHYVGFA 384
            |   ::...:..|     :.||.|:::::.:::.|..|:...:|::.:.::.|.|.||.:.|...
plant   447 NLDMEMDAQTKDYRLVTELIPLFLLVLVIIIVLCPFNILYRSSRFFFLSVLFRCIAAPFYAVHLP 511

  Fly   385 DFWMGDQMNSLVSCIVDHYYTVRFYAISWLRYDRVNNC-----FEPDVMVPITMCLPGWFRFAQC 444
            ||::|||:.|.|..:....:.:.:|.....||.|.|.|     |.  ....|...:|.|.||.||
plant   512 DFFLGDQLTSQVQALRSLEFYICYYGFGDFRYRRRNTCTSNIGFR--TFYFIVAVIPYWLRFLQC 574

  Fly   445 LRRFRDSGSKSMSYLINAGKYSTTFLVVLFS---TLRRNSEGGYANTFSNPYTWLFLSSCVVATI 506
            :||..:  .:.:|:..|..||..|.:.....   ||.|.|..       |...|:|..   |||.
plant   575 IRRMVE--DRDLSHGYNGIKYLLTIVAASLRTAYTLNRGSNW-------NITAWVFSG---VATF 627

  Fly   507 YCYLWDVIRDFGLFRIMRG-ERIFLRKQLVYP-QAFYYFVIVENLVLRLFWA-----VEFTILYH 564
            |...||::.|:||  :.|| :..|||.:|:.| :..||..:|.|::|||.|.     ::|:.|:.
plant   628 YGTYWDIVLDWGL--LQRGCKNSFLRDKLLVPHKTVYYAAMVLNVLLRLVWLQTVLDLKFSFLHR 690

  Fly   565 NLMTPYNMRTISSILEITRRFIWNYVRLENEHLFNCGNFRATRDIHL 611
            ..|.     .:.:.|||.||.|||:.|||||||.|.|.:||.:.:.|
plant   691 ETMV-----ALMACLEIIRRGIWNFFRLENEHLNNVGRYRAFKTVPL 732

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	COG5408	1..162	CDD:227695	62/280 (22%)
		SPX_XPR1_like	2..158	CDD:269898	59/275 (21%)
		EXS	260..597	CDD:281164	108/360 (30%)
SHB1	NP_194265.2	SPX_PHO1_like	2..286	CDD:269897	63/284 (22%)
		SPX	3..291	CDD:281146	63/288 (22%)
		EXS	382..718	CDD:281164	108/360 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940