DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2901 and AT2G03250

DIOPT Version :9

Sequence 1:	NP_570077.1	Gene:	CG2901 / 31338	FlyBaseID:	FBgn0029679	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_001318190.1	Gene:	AT2G03250 / 814854	AraportID:	AT2G03250	Length:	719	Species:	Arabidopsis thaliana

Alignment Length:	781	Identity:	169/781 - (21%)
Similarity:	268/781 - (34%)	Gaps:	229/781 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTYESHLTIEWRQQYMRYGDLKELIK--------------------------QGVENAP-- 37
            |||||.:.|    ||:|.|:.|..||.|:|                          .|:..|.
plant     1 MKFGKDFSS----EWQQAYVDYKYLKTLVKDINRFKRKTNLHGGQISLSSTVLEIEDGITTATIQ 61

  Fly    38 -SPLTSSDYEVQAYYKA-----FEETFLTECQSELTGVNNFFLEKLLEARRKHGHLKLQ---LLA 93
             |...|..||......|     :|..|......|...|..|:.||:.|..::...|..|   |:|
plant    62 VSSTASQRYETTFLMTAEKGGEYELVFFRRLDDEFNKVEKFYREKVDEVVKEAAVLNKQMDALIA 126

  Fly    94 Y--------------------------SREPG--------HTGSDSSLSQRAE------------ 112
            :                          ::.|.        ..|..|...:|::
plant   127 FRLKMKEESTVEMARFALHGVVSPAELAKNPSMKVHMEAIEEGGSSRAGRRSDEDDYYTDEEDHN 191

  Fly   113 ----------------------------------------RSQKKLMTTRQLRY----------- 126
                                                    :|..|:....:|::
plant   192 DVFFTPANNLSKMKSSSSAFIEVLDSIKINNTKEALQSNTKSVLKVSNHTELKFSRDNLRKIEEK 256

  Fly   127 ---AYAEFYLSLVLIQNYQSLNETGFRKICKKYDKNMRSVAAGRWFVENVLDAPFTDVRLLQRMT 188
               |:.||:..|..:::|..||.....||..|||| :.|..|.:.:::.|..:.......:.::.
plant   257 LICAFVEFHRKLWYLKSYSFLNVLALSKILTKYDK-ITSRDAAKSYMKMVDKSCLGSSDEVMKLM 320

  Fly   189 IEVEDLYTTHLANGDRSLAMEKLRVPPLGEPTPPSMVFRAGIALGMLIMLLVATAISYWKRAPLE 253
            ..||..:.....||:|:..|..||..|..|  ...:.|..|...|.:..|:||.......|..|:
plant   321 ENVEATFIKQFTNGNRTKGMNILRPKPKRE--RHRLTFSTGFLGGCMFSLIVALVAIVRTRNILQ 383

  Fly   254 DHTPGLMRLFRGPF-TWVIFNFYM------AANVAGWQQAGVNHILIFEIDPRSHLQPATFLEIA 311
            |  .|..:.....| .:.:|.|.|      |||:..|:|..||:..||.....:.|.....|.:.
plant   384 D--DGQKQYMNTMFPLYSLFGFIMLHMTMYAANIYFWRQYRVNYSFIFGFKQGTELGYKQVLFVG 446

  Fly   312 CTFGILWALSMLGFLYNDLIGVSDP---------YVFPLGLILIMVGLLVVPLPIMNWPARWWTI 367
            .:.|   ||::|..|.| |...:||         .:.||.|::.|..:||||..|....:|::.:
plant   447 FSIG---ALALLCVLAN-LDMETDPKTKDYQALTELLPLFLLIAMFVVLVVPFNIFYRSSRFFFL 507

  Fly   368 KLVGRVITAPLHYVGFADFWMGDQMNSLVSCIVDHYYTVRFYAISWLRY-DRVNNCFEPDV---M 428
            ..:..::.|||:.|...||::.||:.|....:....:.:.:|  .|..: .|.|.|.:..|   .
plant   508 TTLFHMLAAPLYKVTLPDFFLADQLCSQAQTLRSIEFYICYY--GWGDFKQRKNTCKDSQVFNTF 570

  Fly   429 VPITMCLPGWFRFAQCLRRFRDSGSKSMSYLINAGKYSTTFLVVLFSTLRRNSEGGYA----NTF 489
            :.|....|.:.||.||:||..:..:....|  |..||....:.|..         |.|    :..
plant   571 LFIVSAFPFFSRFLQCMRRMLEEKNIEQGY--NGFKYIVIVVAVCL---------GMAYEVDDEK 624

  Fly   490 SNPYTWLFLS--SCVVATIYCYLWDVIRDFGLFRIMRGERIFLRKQLVYP-QAFYYFVIVENLVL 551
            .....|..|.  :..:|.::|..||::.|:||.. ...:..:||..|:.| :..|...:|.:
plant   625 DRQIIWRLLGGITSAMAVVFCTYWDLVYDWGLLN-RTSKNPWLRDNLLIPHKEVYVLAMVSD--- 685

  Fly   552 RLFWAVEFTILYHNLMTPYNMRTISSILEITRRFIWNYVRLENEHLFNCGNFRATRDIHLAALNP 616
                                  .||:||..|   .|:          .||...|....||..|.|
plant   686 ----------------------NISTILRWT---TWH----------GCGRCLAKSWYHLVLLRP 715

  Fly   617 R 617
            :
plant   716 Q 716

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	COG5408	1..162	CDD:227695	54/297 (18%)
		SPX_XPR1_like	2..158	CDD:269898	51/292 (17%)
		EXS	260..597	CDD:281164	85/363 (23%)
AT2G03250	NP_001318190.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940