Protein Alignment CG2901 and xpr1b

DIOPT Version :10

• Sequence 1: NP_570077.1
• Gene: CG2901 / 31338
• FlyBaseID: FBgn0029679
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001119862.1
• Gene: xpr1b / 558034
• ZFINID: ZDB-GENE-060503-266
• Length: 693
• Species: Danio rerio
• Alignment Length: 686
• Identity: 277/686 - (40%)
• Similarity: 396/686 - (57%)
• Gaps: 67/686 - (9%)

  Fly     1 MKFGKTYESHLTIEWRQQYMRYGDLKELIKQGVENAPSPLTSSDYEVQAYYKAFEETFLTECQSE 65
            |||.:...:|:|.|||:||::|...||::....:.|||...:.:..|:.||..|||.|...|:.|
Zfish     1 MKFTEHLSAHITPEWRKQYIQYEAFKEMLYSAQDQAPSIEVTDEDTVKRYYAKFEEKFFQTCEKE 65

  Fly    66 LTGVNNFFLEKLLEARRKHGHLKLQLLA-------YSREPG--HTGSDSSLSQRAERSQKKLMTT 121
            |..:|.|:.|||.||:|:...|:.:|.:       .||..|  |..:...|||: ||.:.:  ..
Zfish    66 LAKINTFYSEKLAEAQRRFATLQNELQSSLDAQRESSRAAGLRHRRTVFHLSQQ-ERCKHR--NI 127

  Fly   122 RQLRYAYAEFYLSLVLIQNYQSLNETGFRKICKKYDKNMRSVAAGRWFVENVLDAPFTDVRLLQR 186
            :.|:.|::||||||:|:||||:||.||||||.||:||...:.....|.|.:|..|||...:.:.:
Zfish   128 KDLQLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKIFETSRGADWRVAHVEVAPFYTCKKITQ 192

  Fly   187 MTIEVEDLYTTHLANGDRSLAMEKLRVPPLG--EPTPPSMVFRAGIALGMLIMLLVATAISYWKR 249
            :..|.|.|.||.|..|||..||::|||||||  :|.|....||.|:..|:.:.|.|...|:  ..
Zfish   193 LISETETLVTTELEGGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLYCGVFVALTVTVIIA--GV 255

  Fly   250 APLEDHTPG------LMRLFRGPFTWVIFNFYMAANVAGWQQAGVNHILIFEIDPRSHLQPATFL 308
            ..|.:|...      |:|::||.|..:.|.|.:..|..||:||||||:||||::||::|......
Zfish   256 VKLVEHFGDNTDVWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRNNLSHQHLF 320

  Fly   309 EIACTFGILWALSMLGFLY--NDLIGVSDPYVFPLGLILIMVGLLVVPLPIMNWPARWWTIKLVG 371
            |||...|:||.:|:|..|:  |.||.:   ::.||.|.......|:.||....:.:|:|.:||:.
Zfish   321 EIAGFLGVLWCVSILSCLFAENTLIPI---HMNPLALYGFFFLFLINPLKTCYYKSRFWLLKLLF 382

  Fly   372 RVITAPLHYVGFADFWMGDQMNSLVSCIVDHYYTVRFYAIS----------WLRY-DRVNNCFEP 425
            ||:|||.|.|||||||:.||:||||..::|..|.:.||::.          |::. :|:  |:..
Zfish   383 RVVTAPFHRVGFADFWLADQLNSLVVVLMDLEYMICFYSLELNWTMSEGELWIKEGERI--CYSY 445

  Fly   426 DVMV-PITMCLPGWFRFAQCLRRFRDSGSKSMSYLINAGKYSTTFLVVLFSTLRRNSEGGYANTF 489
            ...| .:..|||.||||.|||||:||: .::..:|:|||||||||.||:|..|.:...|.....|
Zfish   446 SYGVRAVIKCLPAWFRFVQCLRRYRDT-KRAFPHLVNAGKYSTTFFVVIFEALFKTHSGDERFVF 509

  Fly   490 SNPYTWLFLSSCVVATIYCYLWDVIRDFGLFRIMRGERIFLRKQLVYPQ-AFYYFVIVENLVLRL 553
                .::.::..:|.:.|..|||:..|:|||....||...||:::|||| |:||..|||:::||.
Zfish   510 ----LYIMIACRIVNSCYTLLWDLKMDWGLFDRNAGENTLLREEIVYPQKAYYYCAIVEDVILRF 570

  Fly   554 FWAVEFTILYHNLMTPYNMRTISSI-------LEITRRFIWNYVRLENEHLFNCGNFRATRDIHL 611
            .|.:..     :|...|:...||:|       ||:.|||:||:.|||||||.|||.|||.|||.:
Zfish   571 AWTIPL-----SLEVVYDRPVISNILGTVLPPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISV 630

  Fly   612 AALNPRQERMLESMMDESDGVSNRRKSNERIRLGKE 647
            |.||...:.:||.|||:.|||.|        ||||:
Zfish   631 APLNADDQTLLEQMMDQEDGVRN--------RLGKK 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	SPX_XPR1_like	2..158	CDD:269898	67/164 (41%)
		EXS	259..597	CDD:460816	145/359 (40%)
xpr1b	NP_001119862.1	SPX_XPR1_like	2..164	CDD:269898	67/164 (41%)
		Important for inositol polyphosphate binding. /evidence=ECO:0000250|UniProtKB:P43585	157..164		4/6 (67%)
		EXS	271..616	CDD:460816	145/359 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	674..693