DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2901 and SPAC227.01c

DIOPT Version :9

Sequence 1:	NP_570077.1	Gene:	CG2901 / 31338	FlyBaseID:	FBgn0029679	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_592955.2	Gene:	SPAC227.01c / 2541909	PomBaseID:	SPAC227.01c	Length:	373	Species:	Schizosaccharomyces pombe

Alignment Length:	417	Identity:	97/417 - (23%)
Similarity:	151/417 - (36%)	Gaps:	138/417 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 APLED------HTPGLMRLFRGPFTWVIFNFYMAANVAGWQQAGVNHILIF-EID---------P 298
            |.:||      :.|.::||    |..|:|..|....:.        |:|:. .:|         |
pombe     2 ALIEDLNHFINYFPLVLRL----FFLVVFGLYSFTLIL--------HLLVINRVDVFSLLHTPLP 54

  Fly   299 RSHLQPATFLEIACTFGILWALSMLG--------FLYNDLIGVSDPY----VFPLGLILIMVGLL 351
            .:..|.|.    |..:.:.::||:||        .||  ||..||..    ||..|:|:.|
pombe    55 VNRSQQAN----APLWQLSFSLSILGTLLFVIAESLY--LISGSDELAYVPVFIFGVIVFM---- 109

  Fly   352 VVPLPIMNWPARWWTIKLVGRVITAP-LHYVG--------FADFWMGDQMNSLVSCIVDHYYTVR 407
                |:    .::|..:  .:|.|.. |..:|        |.|....|.:.|....|.|
pombe   110 ----PV----HKFWFFQ--RKVFTRQCLRILGGSYRPDYKFPDVIFSDLLTSYSRVIAD------ 158

  Fly   408 FYAISWLR-------YDRVNNC----FEPDVMVPITMCLPGWFRFAQCL--RRFRDSGSKSMSYL 459
                .||.       .|..||.    :|.:|::.:....|...||.|||  |...|:.|......
pombe   159 ----LWLAGAILIYVTDSPNNSHRKQYENEVIMSMIAAYPYAIRFRQCLIERSSADNSSDKFWST 219

  Fly   460 INAGKYSTTFLVVLFSTLRRNSEGGYANTFSNPYTW-LFLSSCVVATIYCYLWDVIRDFGLFRIM 523
            :|:.||.|.|..:......:       ..||  :.| |:.:|..:.:.|.:.|||..|:.|
pombe   220 LNSIKYFTAFPAIFLGIFAK-------KRFS--FLWFLWNTSSAINSTYSFWWDVSMDWSL---- 271

  Fly   524 RGERIFLRKQL-----------VYPQAFYYFVIVENLVLRLFWAVE---------FTILYHNLMT 568
                .|.::.|           ::|...:..|...:.|||:.|.|.         ||       |
pombe   272 ----PFFKQPLSIQNWKFGVRRLFPTFTFAVVSAIDFVLRMAWVVRVLPEHQSAFFT-------T 325

  Fly   569 PYNMRTISSILEITRRFIWNYVRLENE 595
            .:.: .|...||:.||.:|.:.|:|.|
pombe   326 DFGI-FIMQFLEVFRRCVWVFFRIEAE 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	COG5408	1..162	CDD:227695
		SPX_XPR1_like	2..158	CDD:269898
		EXS	260..597	CDD:281164	93/401 (23%)
SPAC227.01c	NP_592955.2	EXS	15..351	CDD:281164	93/402 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810