Protein Alignment fd3F and foxh1

DIOPT Version :10

• Sequence 1: NP_001356931.1
• Gene: fd3F / 31336
• FlyBaseID: FBgn0264954
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_571577.1
• Gene: foxh1 / 57930
• ZFINID: ZDB-GENE-000616-15
• Length: 472
• Species: Danio rerio
• Alignment Length: 272
• Identity: 67/272 - (24%)
• Similarity: 105/272 - (38%)
• Gaps: 70/272 - (25%)

  Fly   326 SPKSCSSAAMP-AALGGGGNGSAGASAAGGVAGVGSTKTGRKFEELVMEVTSEL-DGNDMIVAEH 388
            |.:||..::.| ..|||..:.|.| .|........:|..|          ..|| |||
Zfish    37 SKRSCHRSSNPLLELGGRLDKSTG-MAQDSCYRAKATNQG----------PWELQDGN------- 83

  Fly   389 VVVEDTSSKAPK-------KPPFTYTELIEYALEDKGE--LTVSGIYQWISDRFPYYKSNDDRWK 444
                  ||...|       |||::|..:|...:::..|  ||:|.|.:.||..||::|.|...|:
Zfish    84 ------SSGGKKKNYQRYPKPPYSYLAMIAMVIQNSPEKKLTLSEILKEISTLFPFFKGNYKGWR 142

  Fly   445 NSVRHNLSINPHFRKGVK---APQGAGHLWAISSGDSAENVLAWEHKKQRLDLFFKMESINRERI 506
            :|||||||....|.|.:|   .|||.|:.|.:              :..|:.|    |.:.|:..
Zfish   143 DSVRHNLSSYDCFVKVLKDPGKPQGKGNFWTV--------------EVNRIPL----ELLKRQNT 189

  Fly   507 QQHQQQQQL----------QQHQQQHQQHS-PQQKQHSAAQQQHMPQASSCMYD---EAAVAVAT 557
            ...:|.:.:          |.:.|.::... |.:........:..|..|...|.   ::..|:.:
Zfish   190 AVSRQDETIFAQDLAPYIFQGYSQPNKSKPLPPESSLPPVPTRQSPPPSEDPYRPKLDSTFAIDS 254

  Fly   558 LTQEMMQTNSGG 569
            |...:...:|.|
Zfish   255 LLHSLRPASSAG 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd3F	NP_001356931.1	Forkhead	401..473	CDD:459732	32/76 (42%)
foxh1	NP_571577.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..56		7/18 (39%)
		FH_FOXH	97..175	CDD:410796	32/91 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	211..246		5/34 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	261..360		2/6 (33%)
		SMAD-interaction domain (SID)	339..465
		Fast/FoxH1 motif 1 (FM1)	357..361
		Fast/FoxH1 motif 2 (FM2)	367..373
		SMAD interaction motif (SIM)	428..448