Protein Alignment fd3F and FOXI3

DIOPT Version :10

• Sequence 1: NP_001356931.1
• Gene: fd3F / 31336
• FlyBaseID: FBgn0264954
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_001129121.1
• Gene: FOXI3 / 344167
• HGNCID: 35123
• Length: 420
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 65/234 - (27%)
• Similarity: 99/234 - (42%)
• Gaps: 71/234 - (30%)

  Fly   274 SAPPHPPSTAVP-----IATSPCSSSSP----------SSASAASASASAISTNQSLGSGLVDQR 323
            :||..||:...|     .|..|.::::|          ...|||:|:|:|.     ||
Human    25 AAPGAPPAARAPYGLADYAAPPAAAANPYLWLNGPGVGGPPSAAAAAAAAY-----LG------- 77

  Fly   324 ARSPKSCSSAAM------PAALGGGGNGS------AGASAAGGVAGVGSTKTGRKFEELVMEVTS 376
            |..|.....||.      |.|.|..|...      |.|:.|...|..|..:.|      .:.:.|
Human    78 APPPPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQPAPAAPASPAAPAGPGELG------WLSMAS 136

  Fly   377 ELDGNDMIVAEHVVVEDTSSKAPKKPPFTYTELIEYALEDKGE--LTVSGIYQWISDRFPYYKSN 439
            ..|...|:                :||::|:.||..|::...|  ||:|.|||:::|.||:|:.:
Human   137 REDLMKMV----------------RPPYSYSALIAMAIQSAPERKLTLSHIYQFVADSFPFYQRS 185

  Fly   440 DDRWKNSVRHNLSINPHFRKGVKAPQ-----GAGHLWAI 473
            ...|:||:|||||:|..|:   |.|:     |.|:.|.:
Human   186 KAGWQNSIRHNLSLNDCFK---KVPRDEDDPGKGNYWTL 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd3F	NP_001356931.1	Forkhead	401..473	CDD:459732	32/78 (41%)
FOXI3	NP_001129121.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	103..122		4/18 (22%)
		FH_FOXI1	142..241	CDD:410827	33/99 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	234..306
		Nuclear localization signal. /evidence=ECO:0000269|PubMed:37041148	235..241
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..396
		9aaTAD. /evidence=ECO:0000250|UniProtKB:D3Z120	406..414