Protein Alignment fd3F and FOXA3

DIOPT Version :10

• Sequence 1: NP_001356931.1
• Gene: fd3F / 31336
• FlyBaseID: FBgn0264954
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_004488.2
• Gene: FOXA3 / 3171
• HGNCID: 5023
• Length: 350
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 79/271 - (29%)
• Similarity: 112/271 - (41%)
• Gaps: 85/271 - (31%)

  Fly   266 QAVNLPEGSAPP-----HPPSTAVP--------IATSPCSSSSPSSASAASASASAISTNQSLGS 317
            :|.:|.|.|..|     :.|.|.||        :..:|.||..|.....||          .|.|
Human     8 EAHDLAEWSYYPEAGEVYSPVTPVPTMAPLNSYMTLNPLSSPYPPGGLPAS----------PLPS 62

  Fly   318 GLVDQRARSPKSCSSAAMPAALGGGGNGSAGASAAGGVAGVGSTKTGRKFEELVMEVTSELDGND 382
            |        |.:..:.|.|......|.|.:|.|::.|....|               ...:.|.:
Human    63 G--------PLAPPAPAAPLGPTFPGLGVSGGSSSSGYGAPG---------------PGLVHGKE 104

  Fly   383 MIVAEHVVVEDTSSKAPK---------KPPFTYTELIEYALED-KGE-LTVSGIYQWISDRFPYY 436
            |               ||         |||::|..||..|::. .|: ||:|.|||||.|.||||
Human   105 M---------------PKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYY 154

  Fly   437 KSNDDRWKNSVRHNLSINPHFRKGVKAPQ--GAGHLWAI--SSGDSAENVLAWEHKKQRLDLFFK 497
            :.|..||:||:||:||.|..|.|..::|.  |.|..||:  |||:..||......:|:     ||
Human   155 RENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKR-----FK 214

  Fly   498 MESINRERIQQ 508
            :|    |::::
Human   215 LE----EKVKK 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd3F	NP_001356931.1	Forkhead	401..473	CDD:459732	37/75 (49%)
FOXA3	NP_004488.2	FH_FOXA3	115..216	CDD:410814	46/105 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..276		1/5 (20%)