Protein Alignment fd3F and foxa1

DIOPT Version :10

• Sequence 1: NP_001356931.1
• Gene: fd3F / 31336
• FlyBaseID: FBgn0264954
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_571359.2
• Gene: foxa1 / 30541
• ZFINID: ZDB-GENE-990415-78
• Length: 427
• Species: Danio rerio
• Alignment Length: 373
• Identity: 91/373 - (24%)
• Similarity: 153/373 - (41%)
• Gaps: 77/373 - (20%)

  Fly   289 SPCSSSS-----------------PSSASAASASASAISTNQSLGSGLVDQRARSPKSCSSAAMP 336
            ||.::||                 .:|.:..|:|.:....|.:||:||      ||.  :.|.||
Zfish    27 SPMTNSSMNPGLSSMNNMNSYMGMSTSGNMTSSSFNMSYANPALGAGL------SPG--TMAGMP 83

  Fly   337 AALGGGGNGSAGASAAGGVAGVGSTKTGRKFEELVMEVTSELDGNDMIVAEHVVVEDTSSKA--- 398
            .  ||..||..|..::.|.|...|.......:...|...:........::.....:...::|
Zfish    84 T--GGAMNGMGGGVSSMGTALSPSNLNAMTAQHSSMNALNPYTSMSPTMSSMTYAQPNLNRARDN 146

  Fly   399 --------PKKPPFTYTELIEYALEDKGE--LTVSGIYQWISDRFPYYKSNDDRWKNSVRHNLSI 453
                    ..|||::|..||..|::....  ||:|.|||||.|.||||:.|..||:||:||:||.
Zfish   147 KTFRRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSF 211

  Fly   454 NPHFRKGVKAPQ--GAGHLWAI--SSGDSAENVLAWEHKKQRLDLFFKMESINRERIQQHQQQQQ 514
            |..|.|..::|.  |.|..|.:  .||:..||......:|:     ||.:    :::...::.:
Zfish   212 NDCFVKVSRSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKR-----FKCD----KKLPDGKRSE- 266

  Fly   515 LQQHQQQHQQHSPQQKQHSAAQQQHMPQASSCMYDEAAVAVATLTQEMMQTNSGGGSTETSQQQQ 579
             .:.:|.....|| ....::::..||        |.:::..:..:......:...||:..|:.:.
Zfish   267 -GKREQSSGSGSP-ASDSTSSKPVHM--------DSSSITSSNQSSSPPSLDHRSGSSANSELKS 321

  Fly   580 QQQQHH---------HHHSHQN--HQNHNQHHQRLLPF--NDLLSDDE 614
            ...|.|         |..:|::  |...:.|:....||  |:|:|..|
Zfish   322 GGPQVHPVSTSLSSLHSMAHESQLHLKGDPHYSFNHPFSINNLMSSSE 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd3F	NP_001356931.1	Forkhead	401..473	CDD:459732	36/75 (48%)
foxa1	NP_571359.2	Forkhead_N	17..156	CDD:369872	27/138 (20%)
		FH_FOXA1	145..255	CDD:410812	42/114 (37%)
		HNF_C	356..416	CDD:430552	6/14 (43%)