Protein Alignment fd3F and Foxg1

DIOPT Version :10

• Sequence 1: NP_001356931.1
• Gene: fd3F / 31336
• FlyBaseID: FBgn0264954
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_036692.1
• Gene: Foxg1 / 24370
• RGDID: 2619
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 248
• Identity: 71/248 - (28%)
• Similarity: 93/248 - (37%)
• Gaps: 66/248 - (26%)

  Fly   256 HLSPHNQIHGQAVNLPEGSAPP------HPPSTAVPIAT-SPCSSSS--------PSSASAASAS 305
            |...|:..|......|:...||      .||:...|.|. :|.:...        |.||:...|.
  Rat    47 HHHHHHHHHHPPPPAPQPPPPPPQQQQQPPPAPQPPQARGAPAADDDKGPQPLLLPPSAALDGAK 111

  Fly   306 ASAISTNQSLGSGLVDQRARSPKSCSSAAMPAALGGGGNGSAGASAAG--GVAGVGSTKTGRKFE 368
            |.|:......|.|..:.....|......|     |.||....||...|  |..|....|...|:|
  Rat   112 ADALGAKGEPGGGPAELAPVGPDEKEKGA-----GAGGEEKKGAGEGGKDGEGGKEGDKKNGKYE 171

  Fly   369 ELVMEVTSELDGNDMIVAEHVVVEDTSSKAPKKPPFTYTELIEYALEDKGE--LTVSGIYQWISD 431
                                            ||||:|..||..|:....|  ||::|||::|..
  Rat   172 --------------------------------KPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMK 204

  Fly   432 RFPYYKSNDDRWKNSVRHNLSINPHFRKGVKAPQ-----GAGHLWAI--SSGD 477
            .||||:.|...|:||:|||||:|..|   ||.|:     |.|:.|.:  ||.|
  Rat   205 NFPYYRENKQGWQNSIRHNLSLNKCF---VKVPRHYDDPGKGNYWMLDPSSDD 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd3F	NP_001356931.1	Forkhead	401..473	CDD:459732	36/78 (46%)
Foxg1	NP_036692.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..172		32/161 (20%)
		FH_FOXG	172..250	CDD:410795	36/80 (45%)
		COG5025	<175..>347	CDD:227358	36/83 (43%)
		Required for interaction with TLE6. /evidence=ECO:0000250|UniProtKB:Q60987	240..335		6/15 (40%)
		Interaction with KDM5B. /evidence=ECO:0000250	374..397
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	418..446