Protein Alignment HIP-R and SGT1

DIOPT Version :10

• Sequence 1: NP_726885.1
• Gene: HIP-R / 31335
• FlyBaseID: FBgn0029676
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_014700.1
• Gene: SGT1 / 854222
• SGDID: S000005583
• Length: 395
• Species: Saccharomyces cerevisiae
• Alignment Length: 286
• Identity: 55/286 - (19%)
• Similarity: 89/286 - (31%)
• Gaps: 95/286 - (33%)

  Fly     8 GDLKKL-----KYFI------DFALENPTFLNMPQLQFVKDFVEKFGGTVPPGQFNGGSAGGKCP 61
            ||..|:     :||:      |:.|....|.....|.:|.|       |:|..:..
Yeast    82 GDRSKIGLVNFRYFVHFFNIKDYELAQSYFKKAKNLGYVDD-------TLPLWEDR--------- 130

  Fly    62 FGGVAGAKANEPANAPEDSEDEKSLSDPESDVELDMEGVIEADSDPAQPMGNYSKKATEEEVEQA 126
                ...|.|:.....:||.::.::...||   ::..|...:...|..|:          ::|.|
Yeast   131 ----LETKLNKKNKKQKDSTNKHTIKPVES---IENRGDNNSSHSPISPL----------KIETA 178

  Fly   127 SELRAQAASAYGQQKFDEAIALYT---------KAIELSPGN------ALFHAKRGQAF------ 170
            .:...:....:.|......|:|:|         ..|.:||.:      :....|.|..|
Yeast   179 PQESPKFKIDWYQSSTSVTISLFTVNLPESKEQVNIYISPNDRRTLSISYQVPKSGSEFQYNAKL 243

  Fly   171 ----------LKL--KKPNACIRDCDVA---------LELNSDLAAGYKFRGRARRLLG------ 208
                      ||:  ||....:...|..         |..:|.|:...|....|.|||.
Yeast   244 SHEVDPKAVSLKIFPKKLEITLSKIDSTQWKKLEEDILTESSRLSDEGKNSDSATRLLSAETASK 308

  Fly   209 ---DFELAAHDLRQACKLDFDEETDE 231
               .:..::.......|||.|||.||
Yeast   309 ERLSYPSSSKKKIDWSKLDIDEEADE 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HIP-R	NP_726885.1	Hip_N	10..47	CDD:271228	10/47 (21%)
		TPR repeat	126..154	CDD:276809	5/36 (14%)
		NlpI	<139..269	CDD:443815	31/144 (22%)
		TPR repeat	159..189	CDD:276809	9/62 (15%)
		TPR repeat	194..222	CDD:276809	5/36 (14%)
		STI1	299..336	CDD:128966
SGT1	NP_014700.1	SGT1	10..395	CDD:227422	55/286 (19%)
		TPR repeat	37..77	CDD:276809
		TPR repeat	82..114	CDD:276809	8/31 (26%)