DRSC/TRiP Functional Genomics Resources

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Protein Alignment HIP-R and st13

DIOPT Version :10

Sequence 1:NP_726885.1 Gene:HIP-R / 31335 FlyBaseID:FBgn0029676 Length:377 Species:Drosophila melanogaster
Sequence 2:NP_001004975.1 Gene:st13 / 448412 XenbaseID:XB-GENE-1015302 Length:382 Species:Xenopus tropicalis


Alignment Length:392 Identity:148/392 - (37%)
Similarity:214/392 - (54%) Gaps:75/392 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 MQTGDLKKLKYFIDFALENPTFLNMPQLQFVKDFVEKFGGTVPPGQFNGGSAGGKCPFGGVAGAK 69
            |....:::|:.|:.....||..|:..:|||.||::...|.:||       :||...|        
 Frog     1 MDPRKVQELREFVRLCESNPNVLHCSELQFFKDWLLSMGASVP-------AAGSTEP-------- 50

  Fly    70 ANEPANAPEDS--EDEKSLSDP------ESDVELDMEGVIEADSDPAQPMGNYSKKATEEEVEQA 126
               |.:|.|::  ::|::.|.|      |||:|:|.||||..|.|..|.||:...:.|||.::||
 Frog    51 ---PTDAKEETPVKEERTPSPPPKPESEESDIEIDNEGVIPGDDDEPQEMGDEDVEVTEEMMDQA 112

  Fly   127 SELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNS 191
            :|.:.:|.:|.|:.:..::|.|:|:||:|:|..|:.:|||...::||:||||.||||..|:.:|.
 Frog   113 NEKKVEAINALGEGELQKSIDLFTEAIKLNPRIAILYAKRASVYIKLQKPNAAIRDCSRAIAINP 177

  Fly   192 DLAAGYKFRGRARRLLGDFELAAHDLRQACKLDFDEETDEWLKEVTPNAKKIEQHRLKQERRQAE 256
            |.|..||:||:|.||||.:|.:||||..|||||:||:....||||.|.|.||.:||.|.||::.|
 Frog   178 DSAQPYKWRGKAHRLLGHWEDSAHDLAMACKLDYDEDASAMLKEVQPRANKIAEHRRKYERKREE 242

  Fly   257 RKIKERQRDQRRARKEQEK----------HNASSGGSSGEFSGGNPGNGNMS------------- 298
            |:|.||:...::|::|.||          ..|..||..|.|.||.||.|.|.             
 Frog   243 REINERKERLKKAKEEHEKAQREEEARRQAGAQFGGFPGGFPGGMPGMGGMGGMPGMGGMGGMPG 307

  Fly   299 --------------------------DILGAMSDPEVSAAIQDILSNPGNITKYASNPKIYNLIK 337
                                      ::|.||.||||.||.||:..||.|::||.:|||:.|||.
 Frog   308 MGGMGGMPGMGGMGGMPGVSEILSDPEVLAAMQDPEVMAAFQDVAQNPANMSKYQNNPKVMNLIT 372

  Fly   338 KI 339
            |:
 Frog   373 KL 374

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HIP-RNP_726885.1 Hip_N 10..47 CDD:271228 11/36 (31%)
TPR repeat 126..154 CDD:276809 9/27 (33%)
NlpI <139..269 CDD:443815 64/129 (50%)
TPR repeat 159..189 CDD:276809 15/29 (52%)
TPR repeat 194..222 CDD:276809 16/27 (59%)
STI1 299..336 CDD:128966 20/36 (56%)
st13NP_001004975.1 Hip_N 3..43 CDD:271228 11/39 (28%)
TPR repeat 112..140 CDD:276809 9/27 (33%)
TPR 118..275 CDD:440225 71/156 (46%)
TPR repeat 145..175 CDD:276809 15/29 (52%)
TPR repeat 180..208 CDD:276809 16/27 (59%)
TPR repeat 213..238 CDD:276809 12/24 (50%)
STI1 332..371 CDD:128966 20/38 (53%)

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