Protein Alignment HIP-R and hip-1

DIOPT Version :9

• Sequence 1: NP_001014719.2
• Gene: HIP-R / 31335
• FlyBaseID: FBgn0029676
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_499811.1
• Gene: hip-1 / 176794
• WormBaseID: WBGene00011735
• Length: 422
• Species: Caenorhabditis elegans
• Alignment Length: 395
• Identity: 152/395 - (38%)
• Similarity: 206/395 - (52%)
• Gaps: 64/395 - (16%)

  Fly    13 LKYFIDFALENPTFLNMPQLQFVKDFVEKFGGTVPPGQFNGGSAGGKCPFGGVAGAKANEPANAP 77
            ||.|:.....||..|:.|:..|.||::...|.|:||..  .....||||.       :.||....
 Worm     7 LKQFVGMCQANPAVLHAPEFGFFKDYLVSLGATLPPKP--ADKPEGKCPM-------SEEPKKET 62

  Fly    78 EDSEDEKSLSDPESDV---------ELDMEGVIEADSDPAQPMGNYSKKATEEEVEQASELRAQA 133
            ..:|     :.||.::         ::|.|||||.:...|.|||:.:|:|||:|:|:|||.|.:|
 Worm    63 PAAE-----ATPEPEIPKPEEIPFPKIDNEGVIEPEEAVALPMGDSAKEATEDEIEKASEERGKA 122

  Fly   134 ASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYK 198
            ..|:....||.|:..:|.|||.:||:|:.||||....||||:|.|.|.|||.|:.:|.|.|.|||
 Worm   123 QEAFSNGDFDTALTHFTAAIEANPGSAMLHAKRANVLLKLKRPVAAIADCDKAISINPDSAQGYK 187

  Fly   199 FRGRARRLLGDFELAAHDLRQACKLDFDEETDEWLKEVTPNAKKIEQHRLKQERRQAERKIKERQ 263
            |||||.||||.:..|..||..|||||:||..:||||||.|||.||:::....||::|:.::.||:
 Worm   188 FRGRANRLLGKWVEAKTDLATACKLDYDEAANEWLKEVEPNAHKIQEYNRAVERQKADIELAERR 252

  Fly   264 RDQRRAR-------KEQEKHNAS-------SGGSSGEFSGGNPGNGNM----------------- 297
            ...|||:       :|:.|..|.       .||..|...||.||.|.|
 Worm   253 ERVRRAQEANKKAAEEEAKRQAEQGDDFDFEGGFPGGMPGGFPGAGGMPGGFPGAPGGGAPGGMG 317

  Fly   298 ---------SDILGAMSDPEVSAAIQDILSNPGNITKYASNPKIYNLIKKI-VPGGDVGAAFGQA 352
                     .:|..|:.||||..|:.||:.||.|:.||.:|||:..||.|: ..|..:...||.|
 Worm   318 AGIEQLFSDPEIAAAIQDPEVLPALMDIMQNPANMMKYINNPKVAKLISKLQSKGAGMPGMFGGA 382

  Fly   353 GEKAG 357
            ...||
 Worm   383 PPSAG 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HIP-R	NP_001014719.2	Hip_N	10..47	CDD:271228	12/33 (36%)
		TPR_11	125..190	CDD:290150	31/64 (48%)
		TPR_2	126..159	CDD:285020	14/32 (44%)
		TPR repeat	126..154	CDD:276809	11/27 (41%)
		TPR repeat	159..189	CDD:276809	16/29 (55%)
		TPR repeat	194..222	CDD:276809	17/27 (63%)
		STI1	299..336	CDD:128966	17/36 (47%)
hip-1	NP_499811.1	HipN	2..41	CDD:375680	12/33 (36%)
		PLN03088	115..>226	CDD:215568	61/110 (55%)
		TPR repeat	148..178	CDD:276809	16/29 (55%)
		TPR repeat	183..211	CDD:276809	17/27 (63%)
		STI1	320..368	CDD:375364	19/47 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	95	1.000	Domainoid score	I4649
eggNOG	1	0.900	-	-		E1_KOG1308
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2921
Inparanoid	1	1.050	249	1.000	Inparanoid score	I2012
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53615
OrthoDB	1	1.010	-	-		D1282821at2759
OrthoFinder	1	1.000	-	-		FOG0003789
OrthoInspector	1	1.000	-	-		otm14757
orthoMCL	1	0.900	-	-		OOG6_104991
Panther	1	1.100	-	-	LDO	PTHR45883
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3214
SonicParanoid	1	1.000	-	-		X3148
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.910