Protein Alignment Rala and Nkiras1

DIOPT Version :10

• Sequence 1: NP_525063.1
• Gene: Rala / 31332
• FlyBaseID: FBgn0015286
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_076015.2
• Gene: Nkiras1 / 69721
• MGIID: 1916971
• Length: 192
• Species: Mus musculus
• Alignment Length: 182
• Identity: 54/182 - (29%)
• Similarity: 94/182 - (51%)
• Gaps: 13/182 - (7%)

  Fly    13 KVIMVGSGGVGKSALTLQFMYDEF---VEDYEPTKADSYRKKVVLD-GEEVQIDILDTAGQEDYA 73
            ||::.|...|||:|:..|.:|...   :||.| |..|.|...|..| |.:.|:.:.||.|.:...
Mouse     6 KVVICGLLSVGKTAILEQLLYGNHTIGMEDCE-TLEDVYMASVETDRGVKEQLHLYDTRGLQKGV 69

  Fly    74 AIRDNYFRSGEGFLCVFSITDDESFQATQEFREQILRVKNDESIPFLLVGNKCDLNDKRKVPLSE 138
            .:..:||...:||:.|:|:.:.||||..:..:::|.:.|:.:.:..:::|||.||:::|:|....
Mouse    70 ELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKLDLSEQRQVDADV 134

  Fly   139 CQLRAQQWA----VPYVETSAKTRENVDKVFFDLMREIRSRKTEDSKATSGR 186
                |||||    |...|.:...|..:.:.|..|..::...:::.|....||
Mouse   135 ----AQQWARSEKVKLWEVTVTDRRTLIEPFTLLASKLSQPQSKSSFPLPGR 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rala	NP_525063.1	RalA_RalB	12..174	CDD:206710	51/168 (30%)
Nkiras1	NP_076015.2	P-loop containing Nucleoside Triphosphate Hydrolases	6..168	CDD:476819	51/166 (31%)
		Effector region	35..43		4/8 (50%)
		Interactions with NFKBIA and NFKBIB. /evidence=ECO:0000250	58..93		9/34 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	168..192		3/15 (20%)