Protein Alignment Rala and RASL11B

DIOPT Version :10

• Sequence 1: NP_525063.1
• Gene: Rala / 31332
• FlyBaseID: FBgn0015286
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_076429.1
• Gene: RASL11B / 65997
• HGNCID: 23804
• Length: 248
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 61/215 - (28%)
• Similarity: 103/215 - (47%)
• Gaps: 26/215 - (12%)

  Fly     7 AGPALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQED 71
            ||..|.|:.:||:.||||:||.::|:...|:.|||....:.|.::|.::||.:.:.:.||.|.:
Human    29 AGRRLVKIAVVGASGVGKTALVVRFLTKRFIGDYERNAGNLYTRQVQIEGETLALQVQDTPGIQ- 92

  Fly    72 YAAIRDN----------YFRSGEGFLCVFSITDDESFQATQEFREQILRVKNDESIPFLLVGNKC 126
               :.:|          ..|..:..:.||||||.:|::...:..:.:.::.....:|.::|.||.
Human    93 ---VHENSLSCSEQLNRCIRWADAVVIVFSITDYKSYELISQLHQHVQQLHLGTRLPVVVVANKA 154

  Fly   127 DLNDKRKV-PLSECQLRAQQWAVPYVETSAKTREN-VDKVFFDLMREIRSRK----TEDSKATS- 184
            ||...::| |....|| |......:.|.|.....| |...|..|.:|:..::    |.:.:.||
Human   155 DLLHIKQVDPQLGLQL-ASMLGCSFYEVSVSENYNDVYSAFHVLCKEVSHKQQPSSTPEKRRTSL 218

  Fly   185 -GRAKD---RCKKRRLKCTL 200
             .|.|.   :..|||.|..|
Human   219 IPRPKSPNMQDLKRRFKQAL 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rala	NP_525063.1	RalA_RalB	12..174	CDD:206710	48/173 (28%)
RASL11B	NP_076429.1	Small GTPase-like	29..246		61/215 (28%)
		RERG_RasL11_like	35..203	CDD:206713	48/172 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	205..226		5/20 (25%)