DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rala and RAP1B

DIOPT Version :9

Sequence 1:NP_525063.1 Gene:Rala / 31332 FlyBaseID:FBgn0015286 Length:201 Species:Drosophila melanogaster
Sequence 2:NP_001010942.1 Gene:RAP1B / 5908 HGNCID:9857 Length:184 Species:Homo sapiens


Alignment Length:191 Identity:90/191 - (47%)
Similarity:135/191 - (70%) Gaps:11/191 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIR 76
            :|::::|||||||||||:||:...|||.|:||..|||||:|.:|.::..::||||||.|.:.|:|
Human     4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMR 68

  Fly    77 DNYFRSGEGFLCVFSITDDESFQATQEFREQILRVKNDESIPFLLVGNKCDLNDKRKVPLSECQL 141
            |.|.::|:||..|:|||...:|...|:.||||||||:.:.:|.:||||||||.|:|.|...:.|.
Human    69 DLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQN 133

  Fly   142 RAQQW-AVPYVETSAKTRENVDKVFFDLMREIRSRKTEDSKATSGRAKDRCKKRRLKCTLL 201
            .|:|| ...::|:|||::.||:::|:||:|:| :|||    ...|:|     :::..|.||
Human   134 LARQWNNCAFLESSAKSKINVNEIFYDLVRQI-NRKT----PVPGKA-----RKKSSCQLL 184

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RalaNP_525063.1 RalA_RalB 12..174 CDD:206710 82/162 (51%)
RAP1BNP_001010942.1 Rap1 3..167 CDD:133375 82/163 (50%)
Interaction with KRIT1. /evidence=ECO:0000269|PubMed:22577140 25..67 20/41 (49%)
Effector region. /evidence=ECO:0000305 32..40 4/7 (57%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0395
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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